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Chapter 63 : Why Is It So Hard to Make an HIV Vaccine?

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Why Is It So Hard to Make an HIV Vaccine?, Page 1 of 2

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Abstract:

The answer lies in the unusual relationship of this particular virus with its host.

Citation: Coffin J. 2016. Why Is It So Hard to Make an HIV Vaccine?, p 259-262. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch63
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Citation: Coffin J. 2016. Why Is It So Hard to Make an HIV Vaccine?, p 259-262. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch63
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My good friend and occasional collaborator, Jonathan Stoye, with a Tootsie Roll Pop. Jonathan likes chocolate, but being British, he does not realize that there is a piece of chocolate inside all that sugar. In this respect, the immune system can be thought of as “British”, in that it does not react to the foreign protein sequences of HIV gp120 under the layer of carbohydrate.

Citation: Coffin J. 2016. Why Is It So Hard to Make an HIV Vaccine?, p 259-262. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch63
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John Coffin is American Cancer Society Professor of Molecular Biology and Microbiology at Tufts University.

Citation: Coffin J. 2016. Why Is It So Hard to Make an HIV Vaccine?, p 259-262. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch63
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Citation: Coffin J. 2016. Why Is It So Hard to Make an HIV Vaccine?, p 259-262. In Schaechter M, In the Company of Microbes: 10 Years of Small Things Considered. ASM Press, Washington, DC. doi: 10.1128/9781555819606.ch63
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