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Chapter 36 : Tuberculosis and Transplantation

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Abstract:

is an important opportunistic pathogen in solid-organ transplant (SOT) recipients ( ), with high morbidity and mortality rates. The frequency of tuberculosis (TB) in SOT recipients ranges from 1.2 to 15% ( ), which is 20 to 74 times higher than that of the general population. Unfortunately, the exact incidence of tuberculosis in SOT recipients is not well known. Table 1 shows the prevalence and incidence rates of TB in SOT recipients in the most numerous series in the literature ( ) and compares them with information available from the Spanish Network of Infection in Transplantation (RESITRA) ( ).

Citation: Aguado J, Silva J, Samanta P, Singh N. 2017. Tuberculosis and Transplantation, p 607-622. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0005-2016
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References

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Tables

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Table 1

Prevalence and incidence of TB in SOT

Citation: Aguado J, Silva J, Samanta P, Singh N. 2017. Tuberculosis and Transplantation, p 607-622. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0005-2016
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Table 2

Risk factors for TB

Citation: Aguado J, Silva J, Samanta P, Singh N. 2017. Tuberculosis and Transplantation, p 607-622. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0005-2016
Generic image for table
Table 3

Suggested regimens for the treatment of latent TB in SOT

Citation: Aguado J, Silva J, Samanta P, Singh N. 2017. Tuberculosis and Transplantation, p 607-622. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0005-2016
Generic image for table
Table 4

Treatment of TB in SOT recipients according to the GESITRA of the Spanish Society of Infectious Diseases and Clinical Microbiology ( )

Citation: Aguado J, Silva J, Samanta P, Singh N. 2017. Tuberculosis and Transplantation, p 607-622. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0005-2016
Generic image for table
Table 5

Risk factors of TB in HSCT recipients

Citation: Aguado J, Silva J, Samanta P, Singh N. 2017. Tuberculosis and Transplantation, p 607-622. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0005-2016

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