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Chapter 3 : The RNA Revolution

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The RNA Revolution, Page 1 of 2

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Abstract:

Genes of a bacterium—its genetic ID card that distinguishes it from other bacteria—are, like our own, carried by the DNA of its chromosome. Bacterial chromosomes are usually circular in shape. Generally, bacteria have a single chromosome, though some bacteria such as have two, and other uncommon genera can have more. , which is carried by ticks and causes Lyme disease, has many linear chromosomes.

Citation: Cossart P. 2018. The RNA Revolution, p 15-22. In The New Microbiology: From Microbiomes to CRISPR. ASM Press, Washington, DC. doi: 10.1128/9781683670117.ch3
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Figures

Image of Figure 5.
Figure 5.

Schematic representation of a double strand of DNA, of its transcribed messenger RNA (mRNA), and of the small protein encoded by the mRNA.

Citation: Cossart P. 2018. The RNA Revolution, p 15-22. In The New Microbiology: From Microbiomes to CRISPR. ASM Press, Washington, DC. doi: 10.1128/9781683670117.ch3
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Image of Figure 6.
Figure 6.

(Left) The three 1965 Nobel Prize winners François Jacob, Jacques Monod, and André Lwoff. (Right) Jacob, Monod, and Lwoff's famous model proposing two possible alternatives for a simultaneous repression of the three genes in the lactose operon. Note that RNA here plays the role of the repressor.

Citation: Cossart P. 2018. The RNA Revolution, p 15-22. In The New Microbiology: From Microbiomes to CRISPR. ASM Press, Washington, DC. doi: 10.1128/9781683670117.ch3
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Image of Figure 7.
Figure 7.

Schematic representation of the chromosome region encoding PocR. In the absence of vitamin B (left), the long transcript AspocR hybridizes with the transcript for , which is then destroyed, preventing the synthesis of PocR. In the presence of B, the messenger RNA allows synthesis of the protein PocR.

Citation: Cossart P. 2018. The RNA Revolution, p 15-22. In The New Microbiology: From Microbiomes to CRISPR. ASM Press, Washington, DC. doi: 10.1128/9781683670117.ch3
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Image of Figure 8.
Figure 8.

Example of an excludon. Once the transcription beginning at P2 is expressed and generates a long transcript, the operon on the right becomes less expressed.

Citation: Cossart P. 2018. The RNA Revolution, p 15-22. In The New Microbiology: From Microbiomes to CRISPR. ASM Press, Washington, DC. doi: 10.1128/9781683670117.ch3
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References

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