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Prions in Humans and Animals

Editors: Beat Hörnlimann1, Detlev Riesner2, Hans Kretzschmar3
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Affiliations: 1: SVISS Consulting, Steinhausen, Switzerland; 2: Heinrich Heine University, Düsseldorf, Germany; 3: Ludwig Maximilian University, Munich, Germany
Content Type: Monograph
Format: Hardcover
Publication Year: 2007

Category: Viruses and Viral Pathogenesis

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This comprehensive work, aimed at both students and researchers alike, systematically covers all aspects of prion diseases (transmissible spongiform encephalopathies), from their history, microbiology, and pathology, to their transmissibility and prevention. The book describes diseases such as Creutzfeldt-Jakob disease, kuru, mad cow disease (BSE), chronic wasting disease and scrapie, highlighting their biochemical, molecular biological, genetic, and clinical aspects.

A renowned editorial team, representing the fields of medicine, veterinary medicine, and molecular biology, brought together 80 internationally respected authors. The book includes chapters by, among many other notable scientists, William J. Hadlow, who discovered the relationship between the human form and animal forms of prion diseases, and Michael P. Alpers, with 45 years of experience in Papua New Guinea investigating the first known human epidemic form, kuru, transmitted by endocannibalism.

Carefully edited with numerous illustrations, this work offers a systematic approach committed to a clear presentation of the current knowledge of prion diseases. It aims to inspire and stimulate interdisciplinary cooperation, innovative research ideas, and effective prevention.

  • Offers more than a simple translation by way of new and up-to-date coverage of prions
  • Extends subject matter for scientists (basic research) and medical doctors, since it is here that the subject of prion diseases continues to be very topical
  • Reduces the subject matter taken from veterinary medicine and agriculture, since the bovine disease BSE has somewhat faded into the background
  • Includes new chapters on immunization and therapy

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