Virology, Genome Sequencing, and Bioinformatics

  • Authors: Erica Suchman1, Mark Gallo2, Carol Blair3
    Affiliations: 1: Colorado State University; 2: Niagara University; 3: Colorado State University
  • Citation: Erica Suchman, Mark Gallo, Carol Blair. 2001. Virology, genome sequencing, and bioinformatics.
  • Publication Date : July 2001
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Students are given instructor-designed computer-generated "sequencing gels" that they are told were generated after sequencing PCR from samples isolated during a hemorrhagic fever outbreak. They must read the sequencing gel and then using this sequence go to the NCBI home page and perform a BLAST search to determine the identity of the virus. The class compares the results of these searches, and students answer a series of questions about the virus for which they have sequence information. The class then attempts to determine the cause of the outbreak as a group.

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