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Preharvest Food Safety in Broiler Chicken Production

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  • Authors: Walid Q. Alali1, Charles L. Hofacre2
  • Editors: Kalmia Kniel3, Siddhartha Thakur4
    Affiliations: 1: College of Public Health, Hamad bin Khalifa University, Doha-Qatar; 2: Department of Population Health, Poultry Diagnostic and Research Center, University of Georgia, Athens, GA 30602; 3: Department of Animal and Food Science, University of Delaware, Newark, DE; 4: North Carolina State University, College of Veterinary Medicine, Raleigh, NC
  • Source: microbiolspec August 2016 vol. 4 no. 4 doi:10.1128/microbiolspec.PFS-0002-2014
  • Received 02 June 2014 Accepted 31 March 2016 Published 19 August 2016
  • Walid Q. Alali, walali@uga.edu
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  • Abstract:

    Preharvest food safety in broiler production is a systematic approach to control the introduction, propagation, and dissemination of and from breeder flocks to the end of their progeny (broilers) life cycle. New and revised more stringent performance standards for these pathogens at the processing plant level require continuous evaluation of the preharvest management practices and intervention strategies used by the poultry industry. The implementation of stricter biosecurity plans, vaccination of breeder flocks for , and usage of feed that is free of animal by-products are some of the measures recommended to control the pathogens. Interventions shown to be effective in experimental settings need to be assessed for their cost-effectiveness and efficiency when applied at the farm level.

  • Citation: Alali W, Hofacre C. 2016. Preharvest Food Safety in Broiler Chicken Production. Microbiol Spectrum 4(4):PFS-0002-2014. doi:10.1128/microbiolspec.PFS-0002-2014.

Key Concept Ranking

Salmonella enterica
Lactic Acid Fermentation


1. World Health Organization. 2005. Drug-resistant Salmonella. http://www.who.int/mediacentre/factsheets/fs139/en/. [PubMed][CrossRef]
2. Flint JA, Van Duynhoven YT, Angulo FJ, DeLong SM, Braun P, Kirk M, Scallan E, Fitzgerald M, Adak GK, Sockett P, Ellis A, Hall G, Gargouri N, Walke H, Braam P. 2005. Estimating the burden of acute gastroenteritis, foodborne disease, and pathogens commonly transmitted by food: an international review. Clin Infect Dis 41:698–704.
3. Scallan E, Hoekstra RM, Angulo FJ, Tauxe RV, Widdowson MA, Roy SL, Jones JL, Griffin PM. 2011. Foodborne illness acquired in the United States: major pathogens. Emerg Infect Dis 17:7–15. [PubMed][CrossRef]
4. FDA. 2005. Human health impact of fluoroquinolone resistant Campylobacter associated with the consumption of chicken, 2001. http://www.fda.gov/downloads/AnimalVeterinary/SafetyHealth/RecallsWithdrawals/UCM152308.pdf.
5. USDA. 2008. U.S. Department of Agriculture, Food Safety and Inspection Service. Improvements for poultry slaughter inspection. Appendix A. Attribution of human salmonellosis to chicken in the USA.
6. Braden CR. 2006. Salmonella enterica serotype Enteritidis and eggs: a national epidemic in the United States. Clin Infect Dis 43:512–517. [PubMed][CrossRef]
7. Painter JA, Hoekstra RM, Ayers T, Tauxe RV, Braden CR, Angulo FJ, Griffin PM. 2013. Attribution of foodborne illnesses, hospitalizations, and deaths to food commodities by using outbreak data, United States, 1998-2008. Emerg Infect Dis 19:407–415. [PubMed][CrossRef]
8. Food and Agriculture Organization of the United Nations. 2010. Poultry meat and eggs. http://www.fao.org/docrep/012/al175e/al175e.pdf.
9. USDA. 2012. Progress report on Salmonella and Campylobacter testing of raw meat and poultry products, CY 1998-2012. http://www.fsis.usda.gov/wps/portal/fsis/topics/data-collection-and-reports/microbiology/annual-progress-reports/2012-annual-report.
10. USDA. 2011. FSIS HACCP verification Campylobacter results: July-December, 2011. http://www.fsis.usda.gov/wps/portal/fsis/topics/data-collection-and-reports/microbiology/campylobacter/ct_index.
11. Buzby JC, Farah HA. 2006. Chicken consumption continues longrun rise. Amber Waves 4:5.
12. CDC. 2011. Foodborne Diseases Active Surveillance Network (FoodNet) 2011 surveillance report. http://www.cdc.gov/foodnet/PDFs/2011_annual_report_508c.pdf.
13. USDA, Food Safety and Inspection Service. 2011. Serotypes profile of Salmonella isolates from meat and poultry products: January 1998 through December 2011. http://www.fsis.usda.gov/wps/wcm/connect/26c0911b-b61e-4877-a630-23f314300ef8/salmonella-serotype-annual-2011.pdf?MOD=AJPERES.
14. FDA. 2010. National Antimicrobial Resistance Monitoring System: Enteric Bacteria (NARMS): 2007 Executive Report. U.S. Department of Health and Human Services, Food and Drug Administration.
15. Le Hello S, Hendriksen RS, Doublet B, Fisher I, Nielsen EM, Whichard JM, Bouchrif B, Fashae K, Granier SA, Jourdan-Da Silva N, Cloeckaert A, Threlfall EJ, Angulo FJ, Aarestrup FM, Wain J, Weill FX. 2011. International spread of an epidemic population of Salmonella enterica serotype Kentucky ST198 resistant to ciprofloxacin. J Infect Dis 204:675–684. [PubMed][CrossRef]
16. Olson CK, Ethelberg S, Van Pelt ERVT. 2008. Epidemiology of Campylobacter jejuni infections in the United States and other industrialized nations, p 163–189. In Nachamkin I, Szymanski CM, Blaser MJ (ed), Campylobacter jejuni: Current and Future Trends. American Society for Microbiology Press, Washington, DC.
17. Swaminathan B, Barrett TJ, Hunter SB, Tauxe RV, CDC PulseNet Task Force. 2001. PulseNet: the molecular subtyping network for foodborne bacterial disease surveillance, United States. Emerg Infect Dis 7:382–389. [PubMed][CrossRef]
18. Altekruse SF, Stern NJ, Fields PI, Swerdlow DL. 1999. Campylobacter jejuni: an emerging foodborne pathogen. Emerg Infect Dis 5:28–35. [PubMed][CrossRef]
19. Lee MD, Newell DG. 2006. Campylobacter in poultry: filling an ecological niche. Avian Dis 50:1–9. [PubMed][CrossRef]
20. Wong TL, Hollis L, Cornelius A, Nicol C, Cook R, Hudson JA. 2007. Prevalence, numbers, and subtypes of Campylobacter jejuni and Campylobacter coli in uncooked retail meat samples. J Food Prot 70:566–573. [PubMed]
21. Madden RH, Moran L, Scates P, McBride J, Kelly C. 2011. Prevalence of Campylobacter and Salmonella in raw chicken on retail sale in the republic of Ireland. J Food Prot 74:1912–1916. [PubMed][CrossRef]
22. Hoang KV, Stern NJ, Saxton AM, Xu F, Zeng X, Lin J. 2011. Prevalence, development, and molecular mechanisms of bacteriocin resistance in Campylobacter. Appl Environ Microbiol 77:2309–2316. [PubMed][CrossRef]
23. Hardy CG, Lackey LG, Cannon J, Price LB, Silbergeld EK. 2011. Prevalence of potentially neuropathic Campylobacter jejuni strains on commercial broiler chicken products. Int J Food Microbiol 145:395–399. [PubMed][CrossRef]
24. Bailey JS. 1988. Integrated colonization control of Salmonella in poultry. Poult Sci 67:928–932. [PubMed][CrossRef]
25. Cox NA, Berrang ME, Cason JA. 2000. Salmonella penetration of egg shells and proliferation in broiler hatching eggs: a review. Poult Sci 79:1571–1574. [PubMed][CrossRef]
26. Lahellec C, Colin P. 1985. Relationship between serotypes of Salmonellae from hatcheries and rearing farms and those from processed poultry carcases. Br Poult Sci 26:179–186. [PubMed][CrossRef]
27. Opitz HM, El-Begearmi M, Flegg P, Beane D. 1993. Effectiveness of five feed additives in chicks infected with Salmonella Enteritidis phage type 13A. Appl Poult Sci. 2:147–153. [CrossRef]
28. Ramirez GA, Sarlin LL, Caldwell DJ, Yezak CR, Jr, Hume ME, Corrier DE, Deloach JR, Hargis BM. 1997. Effect of feed withdrawal on the incidence of Salmonella in the crops and ceca of market age broiler chickens. Poult Sci 76:654–656. [PubMed][CrossRef]
29. Corrier DE, Byrd JA, Hargis BM, Hume ME, Bailey RH, Stanker LH. 1999. Presence of Salmonella in the crop and ceca of broiler chickens before and after preslaughter feed withdrawal. Poult Sci 78:45–49. [PubMed][CrossRef]
30. Dunkley KD, McReynolds JL, Hume ME, Dunkley CS, Callaway TR, Kubena LF, Nisbet DJ, Ricke SC. 2007. Molting in Salmonella Enteritidis-challenged laying hens fed alfalfa crumbles. II. Fermentation and microbial ecology response. Poult Sci 86:2101–2109. [PubMed][CrossRef]
31. Cox NA, Bailey JS, Thomson JE, Juven BJ. 1983. Salmonella and other Enterobacteriaceae found in commercial poultry feed. Poult Sci 62:2169–2175. [PubMed][CrossRef]
32. Davies RH, Wray C. 1997. Distribution of Salmonella contamination in ten animal feedmills. Vet Microbiol 57:159–169. [PubMed][CrossRef]
33. Doyle MP, Roman DJ. 1982. Sensitivity of Campylobacter jejuni to drying. J Food Prot 45:507–510.
34. Humphrey TJ, Henley A, Lanning DG. 1993. The colonization of broiler chickens with Campylobacter jejuni: some epidemiological investigations. Epidemiol Infect 110:601–607. [PubMed][CrossRef]
35. Jones FT, Richardson KE. 2004. Salmonella in commercially manufactured feeds. Poult Sci 83:384–391. [PubMed][CrossRef]
36. Ha SD, Maciorowski KG, Kwon YM, Jones FT, Ricke SC. 1998. Indigenous feed microflora and Salmonella typhimurium marker strain survival in poultry mash diets containing varying levels of protein. Anim Feed Sci Tech 76:23–33. [CrossRef]
37. Maciorowski KG, Jones FT, Pillai SD, Ricke SC. 2004. Incidence, sources, and control of foodborne Salmonella spp. in poultry feeds. Worlds Poult Sci J 60:446–457. [CrossRef]
38. Ricke SC. 2003. Perspectives on the use of organic acids and short chain fatty acids as antimicrobials. Poult Sci 82:632–639. [PubMed][CrossRef]
39. Leeson S, Marcotte M. 1993. Irradiation of poultry feed. I. Microbial status and bird response. Worlds Poult Sci J 49:19–33. [CrossRef]
40. Matlho G, Himathongkham S, Riemann H, Kass P. 1997. Destruction of Salmonella enteritidis in poultry feed by combination of heat and propionic acid. Avian Dis 41:58–61. [PubMed][CrossRef]
41. Jones FT, Axtell RC, Rives DV, Scheideler SE, Tarver FR, Jr, Walker RL, Wineland MJ. 1991. A survey of Salmonella contamination in modern broiler production. J Food Prot 54:502–507.
42. Chambers JR, Lu X. 2002. Probiotics and maternal vaccination for Salmonella control in broiler chickens. J Appl Poult Res 11:320–327. [CrossRef]
43. Hassan JO, Curtiss R, III. 1996. Effect of vaccination of hens with an avirulent strain of Salmonella typhimurium on immunity of progeny challenged with wild-type Salmonella strains. Infect Immun 64:938–944. [PubMed]
44. Berghaus RD, Thayer SG, Maurer JJ, Hofacre CL. 2011. Effect of vaccinating breeder chickens with a killed Salmonella vaccine on Salmonella prevalences and loads in breeder and broiler chicken flocks. J Food Prot 74:727–734. [PubMed][CrossRef]
45. Dórea FC, Cole DJ, Hofacre C, Zamperini K, Mathis D, Doyle MP, Lee MD, Maurer JJ. 2010. Effect of Salmonella vaccination of breeder chickens on contamination of broiler chicken carcasses in integrated poultry operations. Appl Environ Microbiol 76:7820–7825. [PubMed][CrossRef]
46. de Zoete MR, van Putten JPM, Wagenaar JA. 2007. Vaccination of chickens against Campylobacter. Vaccine 25:5548–5557. [PubMed][CrossRef]
47. Ridley AM, Toszeghy MJ, Cawthraw SA, Wassenaar TM, Newell DG. 2008. Genetic instability is associated with changes in the colonization potential of Campylobacter jejuni in the avian intestine. J Appl Microbiol 105:95–104. [PubMed][CrossRef]
48. Wyszynska A, Raczko A, Lis M, Jagusztyn-Krynicka EK. 2004. Oral immunization of chickens with avirulent Salmonella vaccine strain carrying C. jejuni 72Dz/92 cjaA gene elicits specific humoral immune response associated with protection against challenge with wild-type Campylobacter. Vaccine 22:1379–1389. [PubMed][CrossRef]
49. Sizemore DR, Warner B, Lawrence J, Jones A, Killeen KP. 2006. Live, attenuated Salmonella typhimurium vectoring Campylobacter antigens. Vaccine 24:3793–3803. [PubMed][CrossRef]
50. Buckley AM, Wang J, Hudson DL, Grant AJ, Jones MA, Maskell DJ, Stevens MP. 2010. Evaluation of live-attenuated Salmonella vaccines expressing Campylobacter antigens for control of C. jejuni in poultry. Vaccine 28:1094–1105. [PubMed][CrossRef]
51. Quéré P, Girard F. 1999. Systemic adjuvant effect of cholera toxin in the chicken. Vet Immunol Immunopathol 70:135–141. [PubMed][CrossRef]
52. Vervelde L, Janse EM, Vermeulen AN, Jeurissen SHM. 1998. Induction of a local and systemic immune response using cholera toxin as vehicle to deliver antigen in the lamina propria of the chicken intestine. Vet Immunol Immunopathol 62:261–272. [CrossRef]
53. Widders PR, Thomas LM, Long KA, Tokhi MA, Panaccio M, Apos E. 1998. The specificity of antibody in chickens immunised to reduce intestinal colonisation with Campylobacter jejuni. Vet Microbiol 64:39–50. [PubMed][CrossRef]
54. Logan SM, Kelly JF, Thibault P, Ewing CP, Guerry P. 2002. Structural heterogeneity of carbohydrate modifications affects serospecificity of Campylobacter flagellins. Mol Microbiol 46:587–597. [PubMed][CrossRef]
55. Doig P, Kinsella N, Guerry P, Trust TJ. 1996. Characterization of a post-translational modification of Campylobacter flagellin: identification of a sero-specific glycosyl moiety. Mol Microbiol 19:379–387. [PubMed][CrossRef]
56. Cox NA, Berrang ME, Mauldin JM. 2001. Extent of Salmonellae contamination in primary breeder hatcheries in 1998 as compared to 1991. J Appl Poult Res 10:202–205. [CrossRef]
57. Timoney JF, Shivaprasad HL, Baker RC, Rowe B. 1989. Egg transmission after infection of hens with Salmonella Enteritidis phage type 4. Vet Rec 125:600–601. [PubMed]
58. Shivaprasad HL, Timoney JF, Morales S, Lucio B, Baker RC. 1990. Pathogenesis of Salmonella Enteritidis infection in laying chickens. I. Studies on egg transmission, clinical signs, fecal shedding, and serologic responses. Avian Dis 34:548–557. [PubMed][CrossRef]
59. Cason JA, Cox NA, Bailey JS. 1994. Transmission of Salmonella typhimurium during hatching of broiler chicks. Avian Dis 38:583–588. [PubMed][CrossRef]
60. Rizk SS, Ayres JC, Kraft AA. 1966. Effect of holding condition on the development of Salmonellae in artificially inoculated hens’ eggs. Poult Sci 45:825–829. [PubMed][CrossRef]
61. Cox NA, Bailey JS, Mauldin JM, Blankenship LC. 1990. Presence and impact of Salmonella contamination in commercial broiler hatcheries. Poult Sci 69:1606–1609. [PubMed][CrossRef]
62. Cox NA, Bailey JS, Mauldin JM, Blankenship LC, Wilson JL. 1991. Extent of Salmonellae contamination in breeder hatcheries. Poult Sci 70:416–418. [PubMed][CrossRef]
63. Cox NA, Bailey JS, Berrang ME. 1996. Alternative routes for Salmonella intestinal tract colonization of chicks. J Appl Poult Res 5:282–288. [CrossRef]
64. Byrd JA, DeLoach JR, Corrier DE, Nisbet DJ, Stanker LH. 1999. Evaluation of Salmonella serotype distributions from commercial broiler hatcheries and grower houses. Avian Dis 43:39–47. [PubMed][CrossRef]
65. Bhatia TR, McNabb GD. 1980. Dissemination of Salmonella in broiler-chicken operations. Avian Dis 24:616–624. [PubMed][CrossRef]
66. Byrd J, Bailey RH, Wills R, Nisbet D. 2007. Recovery of Campylobacter from commercial broiler hatchery trayliners. Poult Sci 86:26–29. [PubMed][CrossRef]
67. Cox NA, Bailey JS, Richardson LJ, Buhr RJ, Cosby DE, Wilson JL, Hiett KL, Siragusa GR, Bourassa DV. 2005. Presence of naturally occurring Campylobacter and Salmonella in the mature and immature ovarian follicles of late-life broiler breeder hens. Avian Dis 49:285–287. [PubMed][CrossRef]
68. Buhr RJ, Cox NA, Stern NJ, Musgrove MT, Wilson JL, Hiett KL. 2002. Recovery of Campylobacter from segments of the reproductive tract of broiler breeder hens. Avian Dis 46:919–924. [PubMed][CrossRef]
69. Buhr RJ, Musgrove MT, Richardson LJ, Cox NA, Wilson JL, Bailey JS, Cosby DE, Bourassa DV. 2005. Recovery of Campylobacter jejuni in feces and semen of caged broiler breeder roosters following three routes of inoculation. Avian Dis 49:577–581. [PubMed][CrossRef]
70. Hiett KL, Cox NA, Buhr RJ, Stern NJ. 2002. Genotype analyses of Campylobacter isolated from distinct segments of the reproductive tracts of broiler breeder hens. Curr Microbiol 45:400–404. [PubMed][CrossRef]
71. Doyle MP. 1984. Association of Campylobacter jejuni with laying hens and eggs. Appl Environ Microbiol 47:533–536. [PubMed]
72. Cox NA, Stern NJ, Hiett KL, Berrang ME. 2002. Identification of a new source of Campylobacter contamination in poultry: transmission from breeder hens to broiler chickens. Avian Dis 46:535–541. [PubMed][CrossRef]
73. Dunn J. 1996. Pulsed light and pulsed electric field for foods and eggs. Poult Sci 75:1133–1136. [PubMed][CrossRef]
74. Coufal CD, Chavez C, Knape KD, Carey JB. 2003. Evaluation of a method of ultraviolet light sanitation of broiler hatching eggs. Poult Sci 82:754–759. [PubMed][CrossRef]
75. Mitchell BW, Buhr RJ, Berrang ME, Bailey JS, Cox NA. 2002. Reducing airborne pathogens, dust and Salmonella transmission in experimental hatching cabinets using an electrostatic space charge system. Poult Sci 81:49–55. [PubMed][CrossRef]
76. Rodriguez-Romo LA, Yousef AE. 2005. Inactivation of Salmonella enterica serovar Enteritidis on shell eggs by ozone and UV radiation. J Food Prot 68:711–717. [PubMed]
77. Russell SM. 2003. Effect of sanitizers applied by electrostatic spraying on pathogenic and indicator bacteria attached to the surface of eggs. J Appl Poult Res 12:183–189. [CrossRef]
78. Bhatia TRS, McNabb GD, Wyman H, Nayar GPS. 1979. Salmonella isolation from litter as an indicator of flock infection and carcass contamination. Avian Dis 23:838–847. [PubMed][CrossRef]
79. Corry JE, Allen VM, Hudson WR, Breslin MF, Davies RH. 2002. Sources of Salmonella on broiler carcasses during transportation and processing: modes of contamination and methods of control. J Appl Microbiol 92:424–432. [PubMed][CrossRef]
80. Goren E, de Jong WA, Doornenbal P, Bolder NM, Mulder RWAW, Jansen A. 1988. Reduction of Salmonella infection of broilers by spray application of intestinal microflora: a longitudinal study. Vet Q 10:249–255. [PubMed][CrossRef]
81. Ivanov IE. 2001. Treatment of broiler litter with organic acids. Res Vet Sci 70:169–173. [PubMed][CrossRef]
82. Line JE. 2002. Campylobacter and Salmonella populations associated with chickens raised on acidified litter. Poult Sci 81:1473–1477. [PubMed][CrossRef]
83. Pope MJ, Cherry TE. 2000. An evaluation of the presence of pathogens on broilers raised on poultry litter treatment-treated litter. Poult Sci 79:1351–1355. [PubMed][CrossRef]
84. Williams JE. 1980. Formalin destruction of Salmonellae in poultry litter. Poult Sci 59:2717–2724. [PubMed][CrossRef]
85. Vicente JL, Higgins SE, Hargis BM, Tellez G. 2007. Effect of poultry guard litter amendment on horizontal transmission of Salmonella Enteritidis in broiler chicks. Int J Poult Sci 6:314–317. [CrossRef]
86. Corrier DE, Hinton A, Jr, Hargis B, DeLoach JR. 1992. Effect of used litter from floor pens of adult broilers on Salmonella colonization of broiler chicks. Avian Dis 36:897–902. [PubMed][CrossRef]
87. Roll VF, Dai Prá MA, Roll AP. 2011. Research on Salmonella in broiler litter reused for up to 14 consecutive flocks. Poult Sci 90:2257–2262. [PubMed][CrossRef]
88. Rigby CE, Pettit JR. 1981. Effects of feed withdrawal on the weight, fecal excretion and Salmonella status of market age broiler chickens. Can J Comparat Med 45:363–365. [PubMed]
89. Rigby CE, Pettit JR. 1980. Changes in the Salmonella status of broiler chickens subjected to simulated shipping conditions. Can J Comparat Med 44:374–381. [PubMed]
90. Lyon CE, Papa CM, Wilson RL, Jr. 1991. Effect of feed withdrawal on yields, muscle pH, and texture of broiler breast meat. Poult Sci 70:1020–1025. [CrossRef]
91. Buhr RJ, Northcutt JK, Lyon CE, Rowland GN. 1998. Influence of time off feed on broiler viscera weight, diameter, and shear. Poult Sci 77:758–764. [PubMed][CrossRef]
92. Byrd JA, Corrier DE, Hume ME, Bailey RH, Stanker LH, Hargis BM. 1998. Effect of feed withdrawal on Campylobacter in the crops of market-age broiler chickens. Avian Dis 42:802–806. [PubMed][CrossRef]
93. Ramirez GA, Sarlin LL, Caldwell DJ, Yezak CR, Jr, Hume ME, Corrier DE, Deloach JR, Hargis BM. 1997. Effect of feed withdrawal on the incidence of Salmonella in the crops and ceca of market age broiler chickens. Poult Sci 76:654–656. [PubMed][CrossRef]
94. Humphrey TJ, Baskerville A, Whitehead A, Rowe B, Henley A. 1993. Influence of feeding patterns on the artificial infection of laying hens with Salmonella Enteritidis phage type 4. Vet Rec 132:407–409. [PubMed][CrossRef]
95. Corrier DE, Byrd JA, Hargis BM, Hume ME, Bailey RH, Stanker LH. 1999. Survival of Salmonella in the crop contents of market-age broilers during feed withdrawal. Avian Dis 43:453–460. [PubMed][CrossRef]
96. Hargis BM, Caldwell DJ, Brewer RL, Corrier DE, Deloach JR. 1995. Evaluation of the chicken crop as a source of Salmonella contamination for broiler carcasses. Poult Sci 74:1548–1552. [PubMed][CrossRef]
97. Byrd JA, Hargis BM, Caldwell DJ, Bailey RH, Herron KL, McReynolds JL, Brewer RL, Anderson RC, Bischoff KM, Callaway TR, Kubena LF. 2001. Effect of lactic acid administration in the drinking water during preslaughter feed withdrawal on Salmonella and Campylobacter contamination of broilers. Poult Sci 80:278–283. [PubMed][CrossRef]
98. Parker D, Hofacre C, Mathis GF, Quiroz MA, Dibner J, Knight C. 2007. Organic acid water treatment reduced Salmonella horizontal transmission in broiler chickens. http://www.cabi.org/Uploads/animal-science/worlds-poultry-science-association/WPSA-italy-2006/10272.pdf.
99. Byrd JA, Anderson RC, Callaway TR, Moore RW, Knape KD, Kubena LF, Ziprin RL, Nisbet DJ. 2003. Effect of experimental chlorate product administration in the drinking water on Salmonella Typhimurium contamination of broilers. Poult Sci 82:1403–1406. [PubMed][CrossRef]
100. Hinton A, Jr, Buhr RJ, Ingram KD. 2002. Carbohydrate-based cocktails that decrease the population of Salmonella and Campylobacter in the crop of broiler chickens subjected to feed withdrawal. Poult Sci 81:780–784. [PubMed][CrossRef]
101. Hinton M, Linton AH. 1988. Control of Salmonella infections in broiler chickens by the acid treatment of their feed. Vet Rec 123:416–421. [PubMed][CrossRef]
102. Van Immerseel F, Boyen F, Gantois I, Timbermont L, Bohez L, Pasmans F, Haesebrouck F, Ducatelle R. 2005. Supplementation of coated butyric acid in the feed reduces colonization and shedding of Salmonella in poultry. Poult Sci 84:1851–1856. [PubMed][CrossRef]
103. Heres L, Engel B, Urlings HA, Wagenaar JA, van Knapen F. 2004. Effect of acidified feed on susceptibility of broiler chickens to intestinal infection by Campylobacter and Salmonella. Vet Microbiol 99:259–267. [PubMed][CrossRef]
104. Cox NA, McHan F, Bailey JS, Shotts EB. 1994. Effect of butyric or lactic acid on the in vivo colonization of Salmonella Typhimurium. J Appl Poult Res 3:315–318. [CrossRef]
105. Alali WQ, Hofacre CL, Mathis GF, Faltys G. 2013. Effect of essential oil compound on shedding and colonization of Salmonella enterica serovar Heidelberg in broilers. Poult Sci 92:836–841. [PubMed][CrossRef]
106. Alali WQ, Hofacre CL, Mathis GF, Faltys G, Ricke SC, Doyle MP. 2013. Effect of non-pharmaceutical compounds on shedding and colonization of Salmonella enterica serovar Heidelberg in broilers. Food Contr 31:125–128. [PubMed][CrossRef]
107. Roche AJ, Cox NA, Richardson LJ, Buhr RJ, Cason JA, Fairchild BD, Hinkle NC. 2009. Transmission of Salmonella to broilers by contaminated larval and adult lesser mealworms, Alphitobius diaperinus (Coleoptera: tenebrionidae). Poult Sci 88:44–48. [PubMed][CrossRef]
108. Bates C, Hiett KL, Stern NJ. 2004. Relationship of Campylobacter isolated from poultry and from darkling beetles in New Zealand. Avian Dis 48:138–147. [PubMed][CrossRef]
109. McAllister JC, Steelman CD, Skeeles JK. 1994. Reservoir competence of the lesser mealworm (Coleoptera: Tenebrionidae) for Salmonella Typhimurium (Eubacteriales: Enterobacteriaceae). J Med Entomol 31:369–372. [PubMed][CrossRef]
110. Holt PS, Geden CJ, Moore RW, Gast RK. 2007. Isolation of Salmonella enterica serovar Enteritidis from houseflies (Musca domestica) found in rooms containing Salmonella serovar Enteritidis-challenged hens. Appl Environ Microbiol 73:6030–6035. [PubMed][CrossRef]
111. Olsen AR, Hammack TS. 2000. Isolation of Salmonella spp. from the housefly, Musca domestica L., and the dump fly, Hydrotaea aenescens (Wiedemann) (Diptera: Muscidae), at caged-layer houses. J Food Prot 63:958–960. [PubMed]
112. Kinde H, Castellan DM, Kerr D, Campbell J, Breitmeyer R, Ardans A. 2005. Longitudinal monitoring of two commercial layer flocks and their environments for Salmonella enterica serovar Enteritidis and other Salmonellae. Avian Dis 49:189–194. [PubMed][CrossRef]
113. Bailey JS, Stern NJ, Fedorka-Cray P, Craven SE, Cox NA, Cosby DE, Ladely S, Musgrove MT. 2001. Sources and movement of Salmonella through integrated poultry operations: a multistate epidemiological investigation. J Food Prot 64:1690–1697. [PubMed]
114. Rosef O, Kapperud G. 1983. House flies (Musca domestica) as possible vectors of Campylobacter fetus subsp. jejuni. Appl Environ Microbiol 45:381–383. [PubMed]
115. Arends J. 1997. External parasites and poultry pests, p 785–813. In Calneck B (ed), Diseases of Poultry, vol 10. Iowa State University Press, Ames, IA.
116. Skov MN, Madsen JJ, Rahbek C, Lodal J, Jespersen JB, Jørgensen JC, Dietz HH, Chriél M, Baggesen DL. 2008. Transmission of Salmonella between wildlife and meat-production animals in Denmark. J Appl Microbiol 105:1558–1568. [PubMed][CrossRef]
117. Davies RH, Wray C. 1995. Mice as carriers of Salmonella Enteritidis on persistently infected poultry units. Vet Rec 137:337–341. [PubMed][CrossRef]
118. Stern NJ, Fedorka-Cray P, Bailey JS, Cox NA, Craven SE, Hiett KL, Musgrove MT, Ladely S, Cosby D, Mead GC. 2001. Distribution of Campylobacter spp. in selected U.S. poultry production and processing operations. J Food Prot 64:1705–1710. [PubMed]
119. Le Bouquin S, Allain V, Rouxel S, Petetin I, Picherot M, Michel V, Chemaly M. 2010. Prevalence and risk factors for Salmonella spp. contamination in French broiler-chicken flocks at the end of the rearing period. Prev Vet Med 97:245–251. [PubMed][CrossRef]
120. Gradel KO, Rattenborg E. 2003. A questionnaire-based, retrospective field study of persistence of Salmonella Enteritidis and Salmonella Typhimurium in Danish broiler houses. Prev Vet Med 56:267–284. [PubMed][CrossRef]
121. Marin C, Balasch S, Vega S, Lainez M. 2011. Sources of Salmonella contamination during broiler production in Eastern Spain. Prev Vet Med 98:39–45. [PubMed][CrossRef]
122. Wedderkopp A, Gradel KO, Jørgensen JC, Madsen M. 2001. Pre-harvest surveillance of Campylobacter and Salmonella in Danish broiler flocks: a 2-year study. Int J Food Microbiol 68:53–59. [PubMed][CrossRef]
123. Renwick SA, Irwin RJ, Clarke RC, McNab WB, Poppe C, McEwen SA. 1992. Epidemiological associations between characteristics of registered broiler chicken flocks in Canada and the Salmonella culture status of floor litter and drinking water. Can Vet J 33:449–458. [PubMed]
124. Humphrey TJ, Henley A, Lanning DG. 1993. The colonization of broiler chickens with Campylobacter jejuni: some epidemiological investigations. Epidemiol Infect 110:601–607. [PubMed][CrossRef]
125. Evans SJ, Sayers AR. 2000. A longitudinal study of Campylobacter infection of broiler flocks in Great Britain. Prev Vet Med 46:209–223. [PubMed][CrossRef]
126. Gregory E, Barnhart H, Dreesen DW, Stern NJ, Corn JL. 1997. Epidemiological study of Campylobacter spp. in broilers: source, time of colonization, and prevalence. Avian Dis 41:890–898. [PubMed][CrossRef]
127. Blaser MJ, Smith PF, Wang WL, Hoff JC. 1986. Inactivation of Campylobacter jejuni by chlorine and monochloramine. Appl Environ Microbiol 51:307–311. [PubMed]
128. Wang WL, Powers BW, Leuchtefeld NW, Blaser MJ. 1983. Effects of disinfectants on Campylobacter jejuni. Appl Environ Microbiol 45:1202–1205. [PubMed]
129. Kapperud G, Skjerve E, Vik L, Hauge K, Lysaker A, Aalmen I, Ostroff SM, Potter M. 1993. Epidemiological investigation of risk factors for Campylobacter colonization in Norwegian broiler flocks. Epidemiol Infect 111:245–255. [PubMed][CrossRef]
130. Stern NJ, Robach MC, Cox NA, Musgrove MT. 2002. Effect of drinking water chlorination on Campylobacter spp. colonization of broilers. Avian Dis 46:401–404. [PubMed][CrossRef]
131. Siemon CE, Bahnson PB, Gebreyes WA. 2007. Comparative investigation of prevalence and antimicrobial resistance of Salmonella between pasture and conventionally reared poultry. Avian Dis 51:112–117. [PubMed][CrossRef]
132. Alali WQ, Thakur S, Berghaus RD, Martin MP, Gebreyes WA. 2010. Prevalence and distribution of Salmonella in organic and conventional broiler poultry farms. Foodborne Pathog Dis 7:1363–1371. [PubMed][CrossRef]
133. Hoogenboom LA, Bokhorst JG, Northolt MD, van de Vijver LP, Broex NJ, Mevius DJ, Meijs JA, Van der Roest J. 2008. Contaminants and microorganisms in Dutch organic food products: a comparison with conventional products. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 25:1195–1207. [PubMed][CrossRef]
134. Luangtongkum T, Morishita TY, Ison AJ, Huang S, McDermott PF, Zhang Q. 2006. Effect of conventional and organic production practices on the prevalence and antimicrobial resistance of Campylobacter spp. in poultry. Appl Environ Microbiol 72:3600–3607. [PubMed][CrossRef]
135. Esteban JI, Oporto B, Aduriz G, Juste RA, Hurtado A. 2008. A survey of foodborne pathogens in free-range poultry farms. Int J Food Microbiol 123:177–182. [PubMed][CrossRef]
136. Colles FM, Jones TA, McCarthy ND, Sheppard SK, Cody AJ, Dingle KE, Dawkins MS, Maiden MCJ. 2008. Campylobacter infection of broiler chickens in a free-range environment. Environ Microbiol 10:2042–2050. [PubMed][CrossRef]
137. Hanning I, Biswas D, Herrera P, Roesler M, Ricke SC. 2010. Prevalence and characterization of Campylobacter jejuni isolated from pasture flock poultry. J Food Sci 75:M496–M502. [PubMed][CrossRef]
138. Bailey JS, Cosby DE. 2005. Salmonella prevalence in free-range and certified organic chickens. J Food Prot 68:2451–2453. [PubMed]
139. Cui S, Ge B, Zheng J, Meng J. 2005. Prevalence and antimicrobial resistance of Campylobacter spp. and Salmonella serovars in organic chickens from Maryland retail stores. Appl Environ Microbiol 71:4108–4111. [PubMed][CrossRef]
140. Lestari SI, Han F, Wang F, Ge B. 2009. Prevalence and antimicrobial resistance of Salmonella serovars in conventional and organic chickens from Louisiana retail stores. J Food Protect 72:1165–1172. [PubMed]
141. Hanning I, Biswas D, Herrera P, Roesler M, Ricke SC. 2010. Prevalence and characterization of Campylobacter jejuni isolated from pasture flock poultry. J Food Sci 75:M496–M502. [PubMed][CrossRef]
142. Gibson GR, Roberfroid MB. 1995. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 125:1401–1412. [PubMed]
143. Ricke SC, Pillai SD. 1999. Conventional and molecular methods for understanding probiotic bacteria functionality in gastrointestinal tracts. Crit Rev Microbiol 25:19–38. [PubMed][CrossRef]
144. Nisbet D. 2002. Defined competitive exclusion cultures in the prevention of enteropathogen colonisation in poultry and swine. Antonie van Leeuwenhoek 81:481–486. [PubMed][CrossRef]
145. Impey CS, Mead GC, Hinton M. 1987. Influence of continuous challenge via the feed on competitive exclusion of Salmonellas from broiler chicks. J Appl Bacteriol 63:139–146. [PubMed][CrossRef]
146. Zhang G, Ma L, Doyle MP. 2007. Potential competitive exclusion bacteria from poultry inhibitory to Campylobacter jejuni and Salmonella. J Food Prot 70:867–873. [PubMed]
147. Zhang G, Ma L, Doyle MP. 2007. Salmonellae reduction in poultry by competitive exclusion bacteria Lactobacillus salivarius and Streptococcus cristatus. J Food Prot 70:874–878. [PubMed]
148. Doyle MP, Erickson MC. 2006. Reducing the carriage of foodborne pathogens in livestock and poultry. Poult Sci 85:960–973. [PubMed][CrossRef]
149. Corrier DE, Nisbet DJ, Byrd JA II, Hargis BM, Keith NK, Peterson M, Deloach JR. 1998. Dosage titration of a characterized competitive exclusion culture to inhibit Salmonella colonization in broiler chickens during growout. J Food Prot 61:796–801. [PubMed]
150. McReynolds JL, Moore RW, McElroy AP, Hargis BM, Caldwell DJ. 2007. Evaluation of a competitive exclusion culture and megan vac 1 on Salmonella Typhimurium colonization in neonatal broiler chickens. J Appl Poult Res 16:456–463. [CrossRef]
151. Patterson JA, Burkholder KM. 2003. Application of prebiotics and probiotics in poultry production. Poult Sci 82:627–631. [PubMed][CrossRef]
152. Revolledo L, Ferreira AJP, Mead GC. 2006. Prospects in Salmonella control: competitive exclusion, probiotics, and enhancement of avian intestinal immunity. J Appl Poult Res 15:341–351. [CrossRef]
153. Beery JT, Hugdahl MB, Doyle MP. 1988. Colonization of gastrointestinal tracts of chicks by Campylobacter jejuni. Appl Environ Microbiol 54:2365–2370. [PubMed]
154. Schneitz C. 2005. Competitive exclusion in poultry: 30 years of research. Food Contr 16:657–667. [CrossRef]
155. Melendez SN, Hanning I, Han J, Nayak R, Clement AR. 2010. Salmonella enterica isolates from pasture raised poultry exhibit antimicrobial resistance and class I integrons. J Appl Microbiol 109:1957–1966. [PubMed][CrossRef]

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Preharvest food safety in broiler production is a systematic approach to control the introduction, propagation, and dissemination of and from breeder flocks to the end of their progeny (broilers) life cycle. New and revised more stringent performance standards for these pathogens at the processing plant level require continuous evaluation of the preharvest management practices and intervention strategies used by the poultry industry. The implementation of stricter biosecurity plans, vaccination of breeder flocks for , and usage of feed that is free of animal by-products are some of the measures recommended to control the pathogens. Interventions shown to be effective in experimental settings need to be assessed for their cost-effectiveness and efficiency when applied at the farm level.

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