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Paleomicrobiology of Leprosy

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  • Authors: Mark Spigelman1, Mauro Rubini4
  • Editors: Michel Drancourt6, Didier Raoult7
  • VIEW AFFILIATIONS HIDE AFFILIATIONS
    Affiliations: 1: Centre for Clinical Microbiology, Division of Infection & Immunity, University College London, London, UK; 2: Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 3: The Kuvin Center for the Study of Infectious and Tropical Diseases and Ancient DNA, Hadassah Medical School, The Hebrew University, Jerusalem, Israel; 4: Department of Archaeology Foggia University, Foggia, Italy; 5: Anthropological Service of Soprintendenza per i Beni Archeologici del Lazio (Ministry of Culture), Rome, Italy; 6: Aix Marseille Université Faculté de Médecine, Marseille, France; 7: Aix Marseille Université Faculté de Médecine, Marseille, France
  • Source: microbiolspec August 2016 vol. 4 no. 4 doi:10.1128/microbiolspec.PoH-0009-2015
  • Received 20 April 2015 Accepted 05 August 2015 Published 12 August 2016
  • Mark Spigelman, spigelman@btinternet.com
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  • Abstract:

    The use of paleomicrobiological techniques in leprosy has the potential to assist paleopathologists in many important aspects of their studies on the bones of victims, solving at times diagnostic problems. With , because of the unique nature of the organism, these techniques can help solve problems of differential diagnosis. In cases of co-infection with , they can also suggest a cause of death and possibly even trace the migratory patterns of people in antiquity, as well as explain changes in the rates and level of infection within populations in antiquity.

  • Citation: Spigelman M, Rubini M. 2016. Paleomicrobiology of Leprosy. Microbiol Spectrum 4(4):PoH-0009-2015. doi:10.1128/microbiolspec.PoH-0009-2015.

Key Concept Ranking

Infectious Diseases
0.6492897
Immune Systems
0.5695702
Mycobacterium tuberculosis
0.5423077
Mycobacterium leprae
0.53846157
0.6492897

References

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2016-08-12
2017-05-25

Abstract:

The use of paleomicrobiological techniques in leprosy has the potential to assist paleopathologists in many important aspects of their studies on the bones of victims, solving at times diagnostic problems. With , because of the unique nature of the organism, these techniques can help solve problems of differential diagnosis. In cases of co-infection with , they can also suggest a cause of death and possibly even trace the migratory patterns of people in antiquity, as well as explain changes in the rates and level of infection within populations in antiquity.

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Figures

Image of FIGURE 1
FIGURE 1

Stages of bone infiltration.

Source: microbiolspec August 2016 vol. 4 no. 4 doi:10.1128/microbiolspec.PoH-0009-2015
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Image of FIGURE 2
FIGURE 2

Facial appearance of a victim.

Source: microbiolspec August 2016 vol. 4 no. 4 doi:10.1128/microbiolspec.PoH-0009-2015
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Image of FIGURE 3
FIGURE 3

Rhinomaxillary syndrome.

Source: microbiolspec August 2016 vol. 4 no. 4 doi:10.1128/microbiolspec.PoH-0009-2015
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Image of FIGURE 4
FIGURE 4

Nasal changes in leprosy.

Source: microbiolspec August 2016 vol. 4 no. 4 doi:10.1128/microbiolspec.PoH-0009-2015
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Image of FIGURE 5
FIGURE 5

Characteristic pencil shape of the tubular (metatarsal) bones of the foot.

Source: microbiolspec August 2016 vol. 4 no. 4 doi:10.1128/microbiolspec.PoH-0009-2015
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