Probiotics and Diseases of the Genitourinary Tract

Gregor Reid

doi:10.1128/9781555815462.ch21

Chapter 21 : Probiotics and Diseases of the Genitourinary Tract

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Affiliations: 1: Canadian R&D Centre for Probiotics, Lawson Health Research Institute, F2–116, 268 Grosvenor Street, London, Ontario, N6A 4V2, Canada

Content Type: Monograph

Publication Year: 2008

Category: Clinical Microbiology

Book DOI: 10.1128/9781555815462

Chapter DOI: 10.1128/9781555815462.ch21

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Abstract:

Numerous diseases occur in the genitourinary tract of men, women, and children. These disorders cover the gamut of infection, incontinence, cancer, inflammatory problems, and anatomical malfunctions in the urethra, bladder, kidney, prostate, vulva, vagina, cervix, and uterus. The potential for probiotics to counter these ailments is not restricted to infection, but it is in this area that most of the research to date has been done. This chapter begins with conditions under which there is somewhat of a rationale for probiotics to affect the urogenital tract, but for which actual data are sparse. The main goal of probiotics applications is to prevent genitourinary tract infections by populating the vagina with lactobacilli after antifungal agents have reduced the yeast count. Probiotics repopulate the genitourinary tract, compete with other bacteria, and are flushed from the host, necessitating regular, repeated administration. A study was performed to examine the ability of probiotics to prevent bacterial vaginosis (BV) and yeast vaginitis in patients receiving antibiotic therapy. Widespread and growing interest in the use of probiotics for urogenital health has served as an impetus for numerous research studies.

Citation: Reid G. 2008. Probiotics and Diseases of the Genitourinary Tract, p 271-284. In Versalovic J, Wilson M (ed), Therapeutic Microbiology. ASM Press, Washington, DC. doi: 10.1128/9781555815462.ch21

Key Concept Ranking

Microbial Ecology: 0.5453907
Bacterial Pathogenesis: 0.44707555
Lactic Acid Bacteria: 0.42863974
Urinary Tract Infections: 0.4256251
Tumor Necrosis Factor: 0.41346437

0.5453907

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Probiotics and Diseases of the Genitourinary Tract

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/content/10.1128/9781555815462.ch21.ch21fig01

Figure 1

This diagram illustrates that ingestion of probiotic organisms has the potential to affect other parts of the host, either through direct passage to the genitourinary tract or through indirect effects on the host.

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Figure 1

References

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Tables

Probiotics and Diseases of the Genitourinary Tract

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Table 1

Diseases of the urogenital tract for which there is a rationale for probiotics or evidence that probiotics are effective

Table 1

Diseases of the urogenital tract for which there is a rationale for probiotics or evidence that probiotics are effective