, Third Edition

Editors: Irving Nachamkin1, Christine M. Szymanski2, Martin J. Blaser3
Affiliations: 1: Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; 2: Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada; 3: Departments of Medicine and Microbiology, New York University School of Medicine and New York Harbor Veterans Affairs Medical Center, New York, New York
Content Type: Monograph
Format: Electronic, Hardcover
Publication Year: 2008

Category: Bacterial Pathogenesis

MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.

The understanding of clinical aspects, epidemiology, pathogenesis, genomic diversity, and glycobiology of infection has greatly increased. With the publication of this landmark third edition of , all the new findings, knowledge, and research are brought together in one comprehensive, up-to-date volume. As the number of species within the family has expanded, so has our knowledge of this group of organisms in terms of their physiology, population biology, and diversity. Additionally, new findings on the extent of campylobacter in the food supply, transmission of antibiotic resistant campylobacters from food animals to humans, and control of campylobacter at the food source are included.

Organized into six sections with thirty-eight chapters, this volume begins with chapters detailing the campylobacter organism. The next two sections thoroughly describe the clinical and epidemiologic aspects of campylobacter infections, pathogenesis, and immunity. The next section details the emerging field of campylobacter glycobiology, which has provided a structural basis for understanding important polysaccharides and glycolipids from the organism and offers great insight into glycosylation systems, which are present in other prokaryotes and eukaryotes. The volume then covers ground-breaking work on the molecular analyses of and other species. Finally, the volume addresses the growing body of work on improved food safety and intervention.

This volume will be a crucial resource for researchers and clinicians.

Book Summary

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Doody Enterprises

17 August 2013

At A Glance

Understanding of the clinical significance of Campylobacter infection has increased dramatically with the elucidation of its role as a trigger of the Guillain Barre Syndrome. In addition, the entire genomic sequence of Campylobacter jejuni has been determined, permitting detailed analysis of the physiology of the organism, as well as its interaction with its vertebrate hosts. This comprehensive resource is a state-of-the-art compendium of the known and unknowns in the fieldof "Campylobacteriology." A successor to the 1992 volume Campylobacter jejuni: Current Status and Future Trends, it reviews the major developments in the clinical management of Campylobacter jejuni infections, which are now recognized as the most common bacterial cause of food-borne bacterial infections in the United States. While the major focus remains C. jejuni, the editors have broadened the book's scope to include related species. Valuable reading for all clinicians, scientists, ecologists, public health workers, and government
regulators. Key Features Definitive volume summarizing the current understanding of these organisms Offers review chapters by leading investigators Broad scope covers related species.


The curved Gram negative bacilli that make up the Campylobacter species were first noted in the late 1800s, but it has been only in the last 20 years that a clear understanding of the pathogenesis of this species has been recognized. This is the third edition of this book devoted to the recent information known about the Camplyobacter species and closely related Helicobacter and Arcobacter species. The previous edition was published eight years ago and there is a clear need to update the book with developments during that time regarding this group of organisms.


The new edition includes the recent research on the pathogenesis, immune responses to Campylobacter infection, genetic organization of the bacteria, and the development of antibiotic resistance. All of these discoveries have come within the last few years as research techniques and methods have improved. This book provides some clearly needed answers to some of the puzzles associated with these bacteria.


This book is written for scientists studying Campylobacter and the clinicians and public health professionals treating and monitoring infections with this agent. The authors are all well recognized experts in the field and provide some exciting new information that can be used to prevent and treat infections due to Campylobacter.


In 1991, the genera Campylobacter and Arcobacter were placed in a new bacterial family called the Campylobaceraceae. During the next 17 years, numerous other bacteria were reclassified and placed into this family. This was possible due to the study of the genetic arrangement and the physical properties of these bacteria. Also during this time, it became clear that Campylobacter was the causative agent of diarrheal diseases in humans and is associated with acute inflammatory enteritis. These findings allowed public health professionals to determine that the Campylobacter species was the most frequently identified cause of bacterial diarrhea in humans. It was also recognized that a very serious and debilitating disease, Guillain-Barre syndrome, that causes acute neuromuscular paralysis, was highly associated with prior Campylobacter infections. These findings built on each other and it is expected this type of discovery will continue as scientists, clinicians, and public health professionals work together to detect these pathogens. This book will serve as a vital source of information to assist in this effort.


This book will become my primary reference for information regarding Campylobacter infections. I had difficulty deciding which topics I found more interesting. In the end, I realized that the whole book tied into the discovery of how pathogens are identified and the collaboration needed to complete the entire picture.

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Reviewer: Rebecca Horvat, PhD, D(ABMM) (University of Kansas Medical Center)

Review Date: Unknown

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