Manual of Molecular and Clinical Laboratory Immunology, 7th Edition

Editors: Barbara Detrick, Robert G. Hamilton2, James D. Folds3
Affiliations: 2: Johns Hopkins University, School of Medicine Baltimore, MD; 3: University of North Carolina, School of Medicine University of North Carolina Hospitals Chapel Hill, NC
Content Type: Reference
Publication Year: 2006

Category: Immunology

MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.

Renamed , the 7th edition of the continues the tradition of serving as the guide for laboratory directors. The new edition places substantial emphasis on molecular techniques and introduces new material that reflects the significant advances and developments in the field of clinical immunology. This valuable reference will be of practical use to immunologists and will serve the needs of students, instructors, and practitioners of clinical immunology.

The book provides a concise, up-to-date review of the basic principles underlying clinical procedures, features detailed descriptions of the methodology used, and places special focus on the interpretation of laboratory findings. All existing chapters have been significantly revised and updated in the 7th edition.

The molecular theme is woven throughout the sections, with the first section of the book specifically outlining cutting-edge molecular applications soon to be introduced into the standard immunology laboratory. Timely material is introduced in chapters and sections covering transplantation, monitoring of cytokines and chemokines, multiple applications of flow cytometry, allergic diseases, and cancer.

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Doody Enterprises

14 July 2013

At A Glance

Johns Hopkins Univ., Baltimore, MD. Provides a concise review of basic principles underlying each procedure of laboratory findings. Topics include introduction to protein analysis, clinical indications and applications of serum and urine protein electrophoresis, and more. For immunologists. Previous edition: c2002. DNLM: Immunologic Techniques-Laboratory Manuals.


This three-inch thick heavy hardcover book is the 7th edition of the ASM Manual of Molecular and Clinical Laboratory Immunology. This book used to be known as the Manual of Clinical Laboratory Immunology, but had a name change to emphasize the growing contribution of molecular-based testing to Clinical Laboratory Immunology. There are also new editors (Barbara Derrick, Robert Hamilton, James D. Folds) carrying on the tradition of excellence established by Noel Rose.


The purpose of this book is to provide a comprehensive reference for Clinical Immunology Laboratories and as a guide for Directors of Clinical Immunology Laboratories. The authors are world renowned in their areas of expertise, and the editors have done an admirable job of providing the most up to date information and a cohesive text style for this hefty book.


This book would appeal to Clinical Laboratory Scientists (in training or in practice), especially those working in Clinical Immunology Laboratories. Pathologists are also an obvious audience. Other physicians, mid-level providers, medical students or allied health students with an interest in Clinical Immunology and wanting an in-depth "is all" reference book would want to have this book.


This weighty tome consists of 17 sections, each of which is divided into multiple chapters. Each section covers topics of interest that fit the section grouping. At first glance, it was interesting to see how this "horizontal" text combines areas traditionally separated into "vertical" laboratory disciplines; there are entire sections on Clinical Chemistry, molecular testing, Hematopathology, and Medical Microbiology that in and of themselves would be comprehensive texts on their own. Each chapter contains relevant current information, may include "recipes" for performing specific assays, and insight into interpretation of results. One small minor issue for me was that analytical and clinical sensitivity of various new immunological assays was well discussed, but relatively little was included for analytical and clinical specificity. Another very small issue was the inconsistency of organizational names throughout the text - in particular, NCCLS was referred to in one chapter by its original text name, as

NCCLS in another chapter, and only with its current name (CLSI) in the chapter on Laboratory Management. These few minor issues aside, this book remains the authoritative text for Clinical Immunology.


What's to compare? This book *is* the standard for Clinical Immunology textbooks. Make sure your bookshelf and upper body strength is adequate to use this book!

Doody Enterprises

Reviewer: Valerie Ng, PhD MD (Alameda County Medical Center/Highland Hospital)

Review Date: Unknown

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