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Salmonella Genetics, Page 1 of 2
< Previous page Next page > /docserver/preview/fulltext/10.1128/9781555816810/9781555815387_Chap22-1.gif /docserver/preview/fulltext/10.1128/9781555816810/9781555815387_Chap22-2.gifAbstract:
The author and John Roth have both continued to use Salmonella in two ways: as a tool in genetics and in general biology and as a bacterium with interesting metabolism and pathogenicity. Thus, they were both interested in the same types of research problems, and though they did not work in the same place, their joint interests led to first publication together in 1966. The author considers three of the many ways in which John has made major contributions to the field. (i) John has had a major role in supporting stock centers, including the Salmonella Genetic Stock Centre (SGSC) and the Coli Genetic Stock Center (CGSC), and in developing strains and systems for genetic analysis in Salmonella. John has made the strains available to others through his own collection of strains and through the SGSC. (ii) John had a major role in the construction and updating of the linkage map of S. Typhimurium LT2. (iii) John has provided great help to others, often without getting direct recognition, in publishing information about Salmonella and about genetics in general. The author and John had not been surprised to find that strains of S Typhimurium had maintained the same order of the I-CeuI fragments, for they already knew from the linkage maps that the "core" genes of unrelated strains such as E. coli K-12 and S. Typhimurium LT2 had the same order.