Color Plates

(A) Culture of C. burnetii in shell vials detected by immunofluorescence. (B) Culture of C. burnetii in human embryonic fibroblasts, visualized by electronic microscopy.

Detection of C. burnetii on a valve by immunohistochemistry.

Buruli ulcer nodule.

Buruli ulcer. Note the undermined edges and cotton wool-like appearance of the ulcer on the patient's abdomen.

Buruli ulcer scar on upper arm extending below elbow.

Photomicrographs of nodule stage of Buruli ulcer (original magnification, ×5). (A) Hematoxylin-and-eosin stain showing subcutaneous tissue necrosis including septa and ghost adipocytes. The dermis shows elastolysis and focal inflammation around blood vessels. (B) Acid-fast stain showing clumps of red AFB in septa.

Photomicrograph of ulcer stage of Buruli ulcer (original magnification, ×5). A hematoxylin-and-eosin stain shows the border of the ulcer with pseudoepitheliomatous hyperplasia and inflammation at the edge.

Erythema migrans rash of a 12-year-old female resident of a farm in Missouri. The picture was taken on 25 May. The rash followed the bite of an A. americanum tick on 12 May. Photograph courtesy of Edwin J. Masters.

A Borrelia sp. in the papillary dermis of a skin biopsy specimen that was subjected to indirect immunofluorescence with a Borrelia genusspecific monoclonal antibody. The patient developed an erythema migrans rash after travel to a wooded area of western North Carolina (see text). (This is a modified version of a figure that was published in reference 76.)

Giemsa-stained thin blood smear of WAI-type parasites in hamster erythrocytes. Final magnification, × 834. a, ring form; b, tetrad or Maltese cross form; c, periform; d, exoerythrocytic merozoites; e, amoeboid form.

E. histolytica infections in humans. The cyst (A) and trophozoite (B) forms of E. histolytica in stool samples and trophozoites invading colonic epithelium (C) are shown.