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Category: Clinical Microbiology
Laboratory Safety, Page 1 of 2
< Previous page | Next page > /docserver/preview/fulltext/10.1128/9781555817282/9781555817275_Chap28-1.gif /docserver/preview/fulltext/10.1128/9781555817282/9781555817275_Chap28-2.gifAbstract:
This chapter defines the essential components of a laboratory safety program. The key to a safe laboratory environment is the development, implementation, and enforcement of a high-quality safety management program that considers worker safety as a responsibility of the facility. The risk from biological, chemical, physical, and radiological hazards is related to exposure levels, duration of exposure, toxicity or pathogenicity of the hazardous material, safety controls present, and other factors such as the general health or age of the laboratory worker. The Occupational Safety and Health Administration (OSHA) identifies a number of practices that should be implemented to protect the worker from exposure to blood-borne pathogens, including an exposure control and risk assessment plan. The chapter describes various modes of hazard prevention such as handwashing, barrier protection and immunization. While disinfectants destroy all microorganisms, but not necessarily their spores on inanimate surfaces, sterilants are agents that kill all microbial life, including spores, on inanimate surfaces. The chapter provides discusses spill management, both for biological and chemical spills. A training program should include recognition and evaluation of fire hazards, planning to reduce the risk of fire, and all actions to take when a fire occurs. For effective and efficient management of infectious wastes, a comprehensive management plan is essential to ensure the safety of the employees handling the waste, and implementation of cost-effective strategies for waste disposal.
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Example of packing and marking for category A infectious substances. The smallest external dimension of the outer packaging must not be less than 100 mm; the primary receptacle or secondary receptacle must be capable of withstanding, without leakage, an internal pressure of not less than 95 kPa. doi:10.1128/9781555817282.ch28.fA7.1
Example of packing and marking for category A infectious substances. The smallest external dimension of the outer packaging must not be less than 100 mm; the primary receptacle or secondary receptacle must be capable of withstanding, without leakage, an internal pressure of not less than 95 kPa. doi:10.1128/9781555817282.ch28.fA7.1
Example of packing and marking for category B infectious substances. At least one surface of the outer packaging must have a minimum dimension of 100 mm × 100 mm; the primary receptacle or secondary receptacle must be capable of withstanding, without leakage, an internal pressure of not less than 95 kPa. doi:10.1128/9781555817282.ch28.f A7.2
Example of packing and marking for category B infectious substances. At least one surface of the outer packaging must have a minimum dimension of 100 mm × 100 mm; the primary receptacle or secondary receptacle must be capable of withstanding, without leakage, an internal pressure of not less than 95 kPa. doi:10.1128/9781555817282.ch28.f A7.2
Example of packing and marking for exempt specimens. At least one surface of the outer packaging must have a minimum dimension of 100 mm × 100 mm; the outer packaging must be of adequate strength for its capacity, mass, and intended use. doi:10.1128/9781555817282.ch28.f A7.3
Example of packing and marking for exempt specimens. At least one surface of the outer packaging must have a minimum dimension of 100 mm × 100 mm; the outer packaging must be of adequate strength for its capacity, mass, and intended use. doi:10.1128/9781555817282.ch28.f A7.3
Label: infectious substance, category A (class 6). doi:10.1128/9781555817282.ch28.fA8.1
Label: infectious substance, category A (class 6). doi:10.1128/9781555817282.ch28.fA8.1
Label: biological substance, category B. doi:10.1128/9781555817282.ch28.fA8.2
Label: biological substance, category B. doi:10.1128/9781555817282.ch28.fA8.2
Labels: miscellaneous dangerous goods (class 9). doi:10.1128/9781555817282.ch28.fA8.3
Labels: miscellaneous dangerous goods (class 9). doi:10.1128/9781555817282.ch28.fA8.3
Label: package orientation. doi:10.1128/9781555817282.ch28.fA8.4
Label: package orientation. doi:10.1128/9781555817282.ch28.fA8.4
Label: exempt human specimen. doi:10.1128/9781555817282.ch28.fA8.5
Label: exempt human specimen. doi:10.1128/9781555817282.ch28.fA8.5
Elements of a safety management plan
Elements of a safety management plan
WHO classification of microorganisms by risk group a
a From reference 60 .
WHO classification of microorganisms by risk group a
a From reference 60 .
CDC/NIH-recommended biosafety levels for infectious agents a
a From reference 13 .
CDC/NIH-recommended biosafety levels for infectious agents a
a From reference 13 .
Laboratory biosafety level criteria a
a From reference 13 .
Laboratory biosafety level criteria a
a From reference 13 .
Risk assessment and exposure control plan for clinical microbiology laboratory a
a Adapted from reference 26 . Abbreviations: R, required; D, discretionary; P, prohibited; A, one of the required alternatives.
Risk assessment and exposure control plan for clinical microbiology laboratory a
a Adapted from reference 26 . Abbreviations: R, required; D, discretionary; P, prohibited; A, one of the required alternatives.
Risk assessment and exposure control plan for clinical microbiology laboratory a
a Adapted from reference 26 . Abbreviations: R, required; D, discretionary; P, prohibited; A, one of the required alternatives.
Risk assessment and exposure control plan for clinical microbiology laboratory a
a Adapted from reference 26 . Abbreviations: R, required; D, discretionary; P, prohibited; A, one of the required alternatives.
Select agents and toxins a
a From reference 58 .
Select agents and toxins a
a From reference 58 .
Characteristics of hand-hygiene antiseptic agents a
a From reference 8 . +++, Excellent; ++, good, but does not include entire bacterial spectrum; +, fair; −, no activity or not sufficient; F, fast; I, intermediate; S, slow; GP, Gram positive; GN, Gram negative.
Characteristics of hand-hygiene antiseptic agents a
a From reference 8 . +++, Excellent; ++, good, but does not include entire bacterial spectrum; +, fair; −, no activity or not sufficient; F, fast; I, intermediate; S, slow; GP, Gram positive; GN, Gram negative.
Immunizing agents and schedules for healthcare personnel a
a From reference 11 .
Immunizing agents and schedules for healthcare personnel a
a From reference 11 .
Activity levels and hazards of selected germicides a
Activity levels and hazards of selected germicides a
a From references 8 , 15 , and 21 . NA, not available.
Shipping classification examples
Shipping classification examples
Sample laboratory safety audit
Sample laboratory safety audit
Sample laboratory safety audit
Sample laboratory safety audit