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Category: Clinical Microbiology
Bacteroides , Porphyromonas , Prevotella , Fusobacterium , and Other Anaerobic Gram-Negative Rods*, Page 1 of 2
< Previous page | Next page > /docserver/preview/fulltext/10.1128/9781555817381/9781555817381.ch54-1.gif /docserver/preview/fulltext/10.1128/9781555817381/9781555817381.ch54-2.gifAbstract:
Obligately anaerobic, Gram-negative rods of clinical relevance belong mainly to the phyla Bacteroidetes and Fusobacteria. Anaerobes are detected typically in polymicrobial infections associated with mucosal surfaces close to the site where they reside; e.g., members of the Bacteroides fragilis group are often involved in intra-abdominal infections, with considerable morbidity and mortality. When Gram-negative anaerobes gain entrance to the bloodstream and trigger a systemic inflammatory response, this may result in sepsis or infective endocarditis, with a fatal outcome. Knowledge abou
t the resident microbiota and awareness of their role in disease permit clinicians to anticipate the likely infecting species at different body sites. Considering the current reports of considerable frequencies of anaerobic bacteremia and fusobacterial infections, especially Fusobacterium necrophorum-associated invasive diseases, and increasing rates of resistance of Bacteroides spp. to various antimicrobials, training for anaerobic techniques and introduction of advanced methods for the detection and precise identification of anaerobes are needed in clinical microbiology laboratories. New methods, such as matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) analysis, are increasingly used, but novel Gram-negative anaerobes are rather poorly integrated into the databases. Also, most laboratories neither perform the accurate species-level identification of the isolated organism nor test the susceptibilities of anaerobic isolates. Without knowledge of the local susceptibility patterns, the choice of proper antimicrobial therapy can be hampered and make the treatment outcome of anaerobic infections less predictable.
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Recently classified or reclassified genera and species (from 2010 onwards) of non-spore-forming anaerobic Gram-negative rods isolated from humans
Recently classified or reclassified genera and species (from 2010 onwards) of non-spore-forming anaerobic Gram-negative rods isolated from humans
Characteristics of genera representing Gram-negative anaerobic rods frequently isolated from clinical specimens a
Characteristics of genera representing Gram-negative anaerobic rods frequently isolated from clinical specimens a
Common genera of anaerobic Gram-negative rods detected in human infections
Common genera of anaerobic Gram-negative rods detected in human infections
Identification scheme for Bacteroides fragilis group, Parabacteroides, and Odoribacter organisms isolated from humans a
Identification scheme for Bacteroides fragilis group, Parabacteroides, and Odoribacter organisms isolated from humans a
Some phenotypic characteristics of Porphyromonas species of human origin a
Some phenotypic characteristics of Porphyromonas species of human origin a
Biochemical identification scheme for Prevotella species a
Biochemical identification scheme for Prevotella species a
Some phenotypic characteristics of Fusobacterium species a
Some phenotypic characteristics of Fusobacterium species a
Some phenotypic characteristics of Leptotrichia and Sneathia species a
Some phenotypic characteristics of Leptotrichia and Sneathia species a
Biochemical identification of motile Gram-negative anaerobic rods a
Biochemical identification of motile Gram-negative anaerobic rods a
Antimicrobial activities of potential agents against common Gram-negative anaerobes a
Antimicrobial activities of potential agents against common Gram-negative anaerobes a