Chapter 77 : Molecular Detection of Antibacterial Drug Resistance

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This chapter provides an overview of current FDA-cleared molecular assays and selected assays in development for the detection of antibiotic resistance.

Citation: Abbott A, Fang F. 2015. Molecular Detection of Antibacterial Drug Resistance, p 1379-1389. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch77
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Targets of PCR-based assays to detect MRSA. , open reading frame of unknown function and the site of SCC insertion in methicillin-resistant ; , the gene encoding PBP2′, responsible for methicillin resistance; , cassette chromosome recombinase genes; , gene encoding protein A, an example of an -specific target; MRSE, methicillin-resistant . doi:10.1128/9781555817381.ch77.f1

Citation: Abbott A, Fang F. 2015. Molecular Detection of Antibacterial Drug Resistance, p 1379-1389. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch77
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Generic image for table

FDA-cleared molecular assays for the detection of methicillin resistance in and vancomycin resistance in species

Citation: Abbott A, Fang F. 2015. Molecular Detection of Antibacterial Drug Resistance, p 1379-1389. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch77
Generic image for table

FDA-cleared and select RUO molecular assays for the detection of beta-lactamase resistance in Gram-negative bacteria

Citation: Abbott A, Fang F. 2015. Molecular Detection of Antibacterial Drug Resistance, p 1379-1389. In Jorgensen J, Pfaller M, Carroll K, Funke G, Landry M, Richter S, Warnock D (ed), Manual of Clinical Microbiology, Eleventh Edition. ASM Press, Washington, DC. doi: 10.1128/9781555817381.ch77

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