Chapter 3 : The Immunity Alphabet

MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.

Preview this chapter:
Zoom in

The Immunity Alphabet, Page 1 of 2

| /docserver/preview/fulltext/10.1128/9781555817428/9781555815158_Chap03-1.gif /docserver/preview/fulltext/10.1128/9781555817428/9781555815158_Chap03-2.gif


The goal of developing a vaccine targeted at the blood stage of the malaria parasite is to mimic that same condition in infants and young children so that they too may enjoy lifelong immunity with natural boosting by exposure to the blood-sucking, parasite-carrying Anopheles. To “read” the immune system, it would be essential to know its “alphabet”—the building blocks of comprehension. Over the past century, much has been learned about the alphabet of immunity; through investigation, reading, and comprehension, it has provided grist for the mills of vaccine producers (vaccinologists) who are searching for protection against a wide variety of potential assassins, including malaria parasites. This chapter discusses the immunity alphabet such as A for antibody, G for globulin, I for the immune system, N for natural immunity, B for B lymphocytes, and C for cell-mediated immunity. It is hoped that the more we know about the immune responses to a natural malaria infection, as well as the more we understand about the character of the immune systems themselves, the better able we will be to develop a protective malaria vaccine.

Citation: Sherman I. 2009. The Immunity Alphabet, p 49-75. In The Elusive Malaria Vaccine. ASM Press, Washington, DC. doi: 10.1128/9781555817428.ch3
Highlighted Text: Show | Hide
Loading full text...

Full text loading...



This is a required field
Please enter a valid email address
Please check the format of the address you have entered.
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error