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Category: Clinical Microbiology
Urinary Antigen Detection for Legionella spp., Page 1 of 2
< Previous page | Next page > /docserver/preview/fulltext/10.1128/9781555817435/9781555815271_Chap11_4-1.gif /docserver/preview/fulltext/10.1128/9781555817435/9781555815271_Chap11_4-2.gifAbstract:
Patients with Legionnaires' disease excrete soluble serogroup-specific Legionella antigen into their urine. Urinary antigen tests to detect Legionnaires' disease were developed by several groups soon after the 1976 Philadelphia, PA, outbreak of Legionnaires' disease ( 3 , 37 ) and then further refined by Kohler et al. and other groups ( 5 , 16 , 27 – 30 , 34 – 36 ). The antigen being detected has never been extensively purified, but it is known that it is resistant to boiling, is trypsin resistant, has a molecular mass of approximately 10 kDa, and is most likely a lipopolysaccharide ( 29 , 39 ).
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Urinaryantigenkits
Urinaryantigenkits