Chapter 11 : The Double Life of

MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.

Preview this chapter:
Zoom in

The Double Life of , Page 1 of 2

| /docserver/preview/fulltext/10.1128/9781555817442/9781555815004_Chap11-1.gif /docserver/preview/fulltext/10.1128/9781555817442/9781555815004_Chap11-2.gif


This chapter provides a greater understanding of enterotoxigenic , EPEC, EHEC, and VTEC and how they evolved. In the 1960s, appeared in specialist texts as essentially benign and in popular books as essentially benevolent. The nomenclature still needs to be fully resolved, these groups are classified as enterotoxigenic , entero-invasive , enteropathogenic (EPEC), enterohemorrhagic (EHEC), and verocytotoxin (Shiga toxin)-producing (VTEC) varieties. Even during the 1950s, when veterinary microbiologists were confirming the importance of as an agent of diarrhea in calves, its clinical significance was often relegated to footnotes. As illustrated by several chapters in Max Suss-man's monumental Escherichia coli: Mechanisms of Virulence, it is an alarming paradox that this so-called commensal has now become a model for investigating bacterial virulence. Writing about in The Chemical Activities of Bacteria, the Cambridge pioneer Ernest Gale said that this organism is easily grown in large quantities, is non-pathogenic, has wide chemical activities, and has consequently been subjected to more intense biochemical investigation than any other bacterium. One of the benefits of that popularity, vastly extended in the era of molecular genetics, is the existence of countless strain collections.

Citation: Dixon B. 2009. The Double Life of , p 48-52. In Animalcules. ASM Press, Washington, DC. doi: 10.1128/9781555817442.ch11
Highlighted Text: Show | Hide
Loading full text...

Full text loading...


1. Acheson, D. W. K. 1998. Nomenclature of enterotoxins. Lancet 351: 1003.
2. Afza, M.,, J. Hawker,, H. Thurston,, K. Gunn,, and J. Orendi. 2006. An outbreak of Escherichia coli O157 gastroenteritis in a care home for the elderly. Epidemiol. Infect. 134: 1276 1281.
3. Baldwin, T. J. 1998. The 18th C. L. Oakley Lecture. Pathogenicity of enteropathogenic Escherichia coli. J. Med. Microbiol. 47: 283 293.
4. Beutin, L.,, and W. Müller. 1998. Cattle and verotoxigenic Escherichia coli (VTEC), an old relationship? Vet. Rec. 142: 283 284.
5. Centers for Disease Control and Prevention. 2006. Ongoing multistate outbreak of Escherichia coli serotype O157:H7 infections associated with consumption of fresh spinach—United States, September 2006. Morb. Mortal. Wkly. Rep. 55: 10451046.
6. Conedera, G.,, E. Mattiazzi,, F. Russo,, E. Chiesa,, I. Scorzato,, S. Grandesso,, A. Bessegato,, A. Fioravanti,, and A. Caprioli. 2007. A family outbreak of Escherichia coli O157 haemorrhagic colitis caused by pork meat salami. Epidemiol. Infect. 135: 311 314.
7. Gale, E. 1947. The Chemical Activities of Bacteria. University Tutorial Press, London, United Kingdom.
8. Kenny, B.,, R. DeVinney,, M. Stein,, D. J. Reinscheid,, E. A. Frey,, and B. B. Finlay. 1997. Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. Cell 91: 511 520.
9. Sartz, L.,, B. De Jong,, M. Hjertqvist,, L. Plym-Forshell,, R. Alsterlund,, S. Löfdahl,, B. Osterman,, A. Ståhl,, E. Eriksson,, H. B. Hansson,, and D. Karpman. 2008. An outbreak of Escherichia coli O157:H7 infection in southern Sweden associated with consumption of fermented sausage; aspects of sausage production that increase the risk of contamination. Epidemiol. Infect. 136: 370 380.
10. Sussman, M. 1997. Escherichia coli: Mechanisms of Virulence. Cambridge University Press, Cambridge, United Kingdom.
11. Verma, W.,, F. J. Bolton,, D. Fiefield,, P. Lamb,, E. Woloschin,, N. Smith,, and R. McCann. 2007. An outbreak of E. coli O157 associated with a swimming pool: an unusual vehicle of transmission. Epidemiol. Infect. 135: 989 992.

This is a required field
Please enter a valid email address
Please check the format of the address you have entered.
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error