Biofilm Matrix Proteins

Jiunn N. C. Fong; Fitnat H. Yildiz

doi:10.1128/microbiolspec.MB-0004-2014

Chapter 10 : Biofilm Matrix Proteins

Authors: Jiunn N. C. Fong¹, Fitnat H. Yildiz²

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Affiliations: 1: Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, CA 95064; 2: Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, CA 95064

Content Type: Monograph

Publication Year: 2015

Category: Environmental Microbiology

Book DOI: 10.1128/9781555817466

Chapter DOI: 10.1128/microbiolspec.MB-0004-2014

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Biofilm Matrix Proteins, Page 1 of 2

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Abstract:

Microorganisms in the natural environment typically live on or in close association with surfaces and predominantly exist as biofilms, surface attached microbial communities composed of cells and extracellular matrix ( 1 – 4 ). The exact compositions of biofilm matrices differ greatly between different microorganisms and growth conditions under which biofilms are formed but generally consist of exopolysaccharides, proteins, and nucleic acids. Proteinaceous components include cell surface adhesins, protein subunits of flagella and pili, secreted extracellular proteins, and proteins of outer membrane vesicles.

Citation: Fong J, Yildiz F. 2015. Biofilm Matrix Proteins, p 201-222. In Ghannoum M, Parsek M, Whiteley M, Mukherjee P (ed), Microbial Biofilms, Second Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MB-0004-2014

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Biofilm Matrix Proteins

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Figure 1

Colony morphology of V. cholerae rugose variant and mutant strains unable to produce RbmA, RbmC, and Bap1 matrix proteins. Bar = 0.5 mm.

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Figure 1

Colony morphology of V. cholerae rugose variant and mutant strains unable to produce RbmA, RbmC, and Bap1 matrix proteins. Bar = 0.5 mm.

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Figure 2

Domain organization of V. cholerae RbmA, Bap1, and RbmC. FnIII, fibronectin type III; VCBS, Vibrio-Colwellia-Bradyrhizobium-Shewanella repeat; FG-GAP, phenyl-alanyl-glycyl (FG) and glycyl-alanyl-prolyl (GAP).

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Figure 2

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Figure 3

Domain organization of S. aureus Bap and S. enterica BapA. EF-hand calcium-binding motifs EF1 to 4 in Bap are indicated. LPxTG is the cell-wall anchoring motif. The repeats in the core regions of S. enterica BapA share 29% identity with the C repeats of S. aureus Bap.

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Figure 3

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Tables

Biofilm Matrix Proteins

/content/10.1128/9781555817466.chap10.tab10-1

TABLE 1

Members of the Bap family a

TABLE 1

Members of the Bap family a