Distinguishing Pathovars from Nonpathovars: Streptococcus pneumoniae

doi:10.1128/9781555817688.ch8

Chapter 8 : Distinguishing Pathovars from Nonpathovars: Streptococcus pneumoniae

Author: Lee W. Riley¹

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Affiliations: 1: School of Public Health University of California, Berkeley, California

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Publication Year: 2004

Category: Microbial Genetics and Molecular Biology

Book DOI: 10.1128/9781555817688

Chapter DOI: 10.1128/9781555817688.ch8

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Abstract:

One defining feature of a pathovar is that, in a human host, it colonizes the same nonsterile ecologic niche in which nonpathovars establish themselves as commensals. This chapter talks about a bacterial organism, Streptococcus pneumoniae, that colonizes the oro- and naso-pharynx of the human host in similar proportions worldwide. The major current epidemiologic concerns regarding pneumococcal infections include the determinants of the emergence and spread in the community of drug-resistant strains of the pneumococcus and the relationship between asymptomatic carriage and disease. The latter addresses the issue of whether or not any strain that asymptomatically colonizes a host is also capable of causing invasive disease. Molecular epidemiologic approaches to these issues are discussed.

Citation: Riley L. 2004. Distinguishing Pathovars from Nonpathovars: Streptococcus pneumoniae, p 209-227. In Molecular Epidemiology of Infectious Diseases. ASM Press, Washington, DC. doi: 10.1128/9781555817688.ch8

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Tables

Distinguishing Pathovars from Nonpathovars: Streptococcus pneumoniae

/content/10.1128/9781555817688.chap8.tab8-1

Table 8.1

International pneumococcal clones recognized to have contributed to the increase in antimicrobial resistance worldwide a

a Adapted from reference 44 .

b ATCC, American Type Culture Collection.

10.1128/9781555817688/tab8-1_thmb.gif

10.1128/9781555817688/tab8-1.gif

Table 8.1

International pneumococcal clones recognized to have contributed to the increase in antimicrobial resistance worldwide a

a Adapted from reference 44 .

b ATCC, American Type Culture Collection.