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Category: Microbial Genetics and Molecular Biology
Distinguishing Pathovars from Nonpathovars: Streptococcus pneumoniae, Page 1 of 2
< Previous page | Next page > /docserver/preview/fulltext/10.1128/9781555817688/9781555812683_Chap08-1.gif /docserver/preview/fulltext/10.1128/9781555817688/9781555812683_Chap08-2.gifAbstract:
One defining feature of a pathovar is that, in a human host, it colonizes the same nonsterile ecologic niche in which nonpathovars establish themselves as commensals. This chapter talks about a bacterial organism, Streptococcus pneumoniae, that colonizes the oro- and naso-pharynx of the human host in similar proportions worldwide. The major current epidemiologic concerns regarding pneumococcal infections include the determinants of the emergence and spread in the community of drug-resistant strains of the pneumococcus and the relationship between asymptomatic carriage and disease. The latter addresses the issue of whether or not any strain that asymptomatically colonizes a host is also capable of causing invasive disease. Molecular epidemiologic approaches to these issues are discussed.
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International pneumococcal clones recognized to have contributed to the increase in antimicrobial resistance worldwide a
a Adapted from reference 44 .
b ATCC, American Type Culture Collection.
International pneumococcal clones recognized to have contributed to the increase in antimicrobial resistance worldwide a
a Adapted from reference 44 .
b ATCC, American Type Culture Collection.