Natural Pathogens of Laboratory Animals: Their Effects on Research

Author: David G. Baker1
Affiliations: 1: School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana
Content Type: Reference
Publication Year: 2003

Category: Clinical Microbiology

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This important new book informs laboratory animal veterinarians, animal caretakers, research scientists, and others, how natural pathogens of laboratory animals, many of which cause no outward signs of disease, can alter host physiology and compromise the validity of research findings.

This text opens with an historical perspective on changes in the general awareness of laboratory animal pathogens and an overview of the important distinction between infection and disease. Brief descriptions of housing systems for pathogen exclusion or containment, and of approaches to pathogen surveillance are also provided.

The body of the text presents chapters on the most common natural pathogens found in a wide variety of laboratory animals. For each pathogen there is a description of the agent, epidemiology, clinical signs, pathology, interference with research, and methods of diagnosis and control. Each description concludes with a convenient table indicating the organ systems affected.

is an essential resource for everyone working with laboratory animals.

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