Chapter 16 : Emerging Infectious Diseases

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This chapter is devoted to select emerging and reemerging infectious disease entities and, wherever applicable, typical clinical manifestations and laboratory findings are also described. The majority of cases of human monocytic ehrlichia (HME) and human granulocyte ehrlichia (HGE) are diagnosed by retrospective serologic testing, and the most commonly used serologic test is the indirect fluorescent-antibody test, which is available through commercial laboratories and public health laboratories. The majority of cat scratch disease is caused by ; the different clinical presentations associated with infection appear to predominantly be due to the host immune system although there may be differences in virulence between strains as well. Nucleic acid detection techniques for species were first described by Relman based on amplification of the 16S rRNA gene. The hantavirus pulmonary syndrome begins with a prodromal phase consisting of sudden onset of fever, myalgias, headache, and backache. Immunohistochemistry staining of tissue samples can also be used to look for hantavirus antigens. This study is usually done as a confirmatory test in appropriate patients. PCR testing on tissue or blood cells can also be used to detect hantavirus RNA.

Citation: Suh B, Kostman J, Maniglia R. 2002. Emerging Infectious Diseases, p 396-412. In Truant A (ed), Manual of Commercial Methods in Clinical Microbiology. ASM Press, Washington, DC. doi: 10.1128/9781555817961.ch16
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Tilapias (also known as St. Peter's fish or Hawaiian sunfish). Courtesy of Donald E. Low.

Citation: Suh B, Kostman J, Maniglia R. 2002. Emerging Infectious Diseases, p 396-412. In Truant A (ed), Manual of Commercial Methods in Clinical Microbiology. ASM Press, Washington, DC. doi: 10.1128/9781555817961.ch16
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1. Ablashi, D. V.,, P. Lusso,, C. L. Hung,, S. Z. Salahuddin,, S. F. Josephs,, T. Liana,, B. Kramarsky,, and P. Biberfield. 1988. Utilization of human hematopoietic cell lines for the propagation and characterization of HBLV (human herpesvirus 6). Int. J. Cancer 42: 787 791.
2. Anderson, B.,, K. Sims,, R. Regnery,, L. Robinson,, M. J. Schmidt,, S. Goral,, C. Huger,, and K. Edwards. 1994. Detection of Rochalimaea henselae DNA in specimens from cat scratch disease patients by PCR. J. Clin. Microbiol. 32: 942 948.
3. Anderson, B.,, C. Kelly,, R. Threlkel,, and K. Edwards. 1993. Detection of Rochalimaea henselae in cat-scratch disease skin test antigens. J. Infect. Dis. 168: 1034 1036.
4. Anderson, B. E.,, and M. A. Neuman. 1997. Bartonella spp. as emerging human pathogens. Clin. Microbiol. Rev. 10: 203 219.
5. Anderson, B. E.,, K. G. Sims,, J. G. Olson,, J. E. Childs,, J. F. Piesman,, C. M. Happ,, G. O. Maupin,, and B. J. B. Johnson. 1993. Amblyomma americanum: a potential vector of human ehrlichiosis. Am. J. Trop. Med. Hyg. 49: 239 244.
6. Anderson, B. E.,, J. W. Summer,, J. E. Dawson,, T. Tzianabos,, C. R. Greene,, J. G. Olson,, D. B. Fishbein,, M. Olsen-Rasmussen,, B. P. Hollowau,, E. H. George,, and A. F. Azad. 1992. Detection of the etiologic agent of human ehrlichiosis by polymerase chain reaction. J. Clin. Microbiol. 30: 775 780.
7. Baker, J. A. 1946. A rickettsial infection in Canadian voles. J. Exp. Med. 84: 37 55.
8. Bakken, J. S.,, J. Krueth,, C. Wilson-Nordskog,, R. L. Tilden,, K. Asanovich,, and J. S. Dumler. 1996. Clinical and laboratory characteristics of human granulocytic ehrlichiosis. JAMA 275: 199 205.
9. Bass, J. W.,, J. M. Vincent,, and D. A. Person. 1997. The expanding spectrum of Bartonella infections: II. Cat-scratch disease. Pediatr. Infect. Dis. J. 16: 163 179.
10. Bell, B. P.,, M. Goldoft,, P. M. Griffin,, M. A. Davis,, D. C. Gordon,, P. I. Tarr,, C. A. Bartleson,, J. H. Lewis,, T. J. Barrett,, J. G. Wells,, R. Barson,, and J. Kobayashi. 1994. A multistate outbreak of Escherichia coli O157:H7-associated bloody diarrhea and hemolytic uremic syndrome from hamburgers: the Washington experience. JAMA 272: 1349 1353.
11. Bergmans, A. M. C.,, J.-W. Groothedde,, J. F. P. Schellekens,, J. D. A. Vanemden,, J. M. Ossewaarde,, and L. M. Schouls. 1995. Etiology of cat-scratch disease: comparison of polymerase chain reaction detection of Bartonella (formerly Rochalimaea) and Afipia felis DNA with serology and skin tests. J. Infect. Dis. 171: 916 923.
12. Besser, R. E.,, S. M. Lett,, J. T. Weber,, M. P. Doyle,, T. J. Barrett,, J. G. Wells,, and P. M. Griffin. 1993. An outbreak of diarrhea and hemolytic uremic syndrome from Escherichia coli O157:H7 in fresh-pressed apple cider. JAMA 269: 2217 2220.
13. Birtles, R. J.,, T. G. Harrison,, N. A. Saunders,, and D. Molyneux. 1995. Proposals to unify the genera Grahamella and Bartonella, with descriptions of Bartonella talpae comb. nov., Bartonella peromysci comb. nov., and three new species, Bartonella grahamii sp. nov., Bartonella taylorii sp. nov., and Bartonella doshiae sp. nov. Int. J. Syst. Bacteriol. 45: 1 8.
14. Bopp, C. A.,, F. W. Brenner,, J. G. Wells,, and N. A. Strockbine,. 1999. Escherichia, Shigella, and Salmonella, p. 459 474. In P. R. Murray,, E. J. Baron,, M. A. Pfaller,, F. C. Tenover,, and R. H. Yolken (ed.), Manual of Clinical Microbiology, 7th ed. American Society for Microbiology, Washington, D.C..
15. Breitschwerdt, E. B.,, D. L. Kordick,, D. E. Malarkey,, B. Keene,, T. L. Hadfield,, and K. Wilson. 1995. Endocarditis in a dog due to infection with a novel Bartonella subspecies. J. Clin. Microbiol. 33: 154 160.
16. Brenner, D. J.,, S. P. O’Connor,, D. G. Hollis,, R. E. Weaver,, and A. G. Steigerwalt. 1991. Molecular characterization and proposal of neotype strain for Bartonella bacilliformis. J. Clin. Microbiol. 29: 1299 1302.
17. Brenner, D. J.,, S. P. O’Connor,, H. H. Winkler,, and A. G. Steigerwalt. 1993. Proposals to unify the genera Bartonella and Rochalimaea, with descriptions of Bartonella quintana comb. nov., Bartonella vinsonii comb. nov., Bartonella henselae comb. nov., and Bartonella elizabethae comb. nov., and to remove the family Bartonellaceae from the order Rickettsiales. Int. J. Syst. Bacteriol. 43: 777 786.
18. Brenner, S. A.,, J. A. Rooney,, P. Manzewitsch,, and R. L. Regnery. 1997. Isolation of Bartonella ( Rochalimaea) henselae: effects of methods of blood collecton and handling. J. Clin. Microbiol. 35: 544 547.
19. Brouqui, P.,, and D. Raoult. 1992. In vitro antibiotic susceptibility of the newly recognized agent of ehrlichiosis in humans. Ehrlichia chaffeensis. Antimicrob. Agents Chemother. 36: 2799 2803.
20. Butler, J. C.,, and C. J. Peters. 1994. Hantavirus and hantavirus pulmonary syndrome. Clin. Infect. Dis. 19: 387 394.
21. Bwaka, M. A.,, M. Bonnet,, P. Calain,, R. Colebunders,, A. DeRoo,, Y. Guimard,, K. R. Katwiki,, K. Kibadi,, M. A. Kipasa,, K. J. Kuvula,, B. B. Mapanda,, M. Massamba,, K. D. Mupapa,, J. J. Muyembe-Tamfun,, E. Ndaberey,, C. J. Peters,, P. E. Rollin,, and E. VandenEnden. 1999. Ebola hemorrhagic fever in Kikwit, Democratic Republic of Congo (former Zaire): clinical observations. J. Infect. Dis. 179( Suppl. 1): S1 S7.
22. Carithers, H. A. 1978. Oculoglandular disease of Parinaud: a manifestation of cat-scratch disease. Am. J. Dis. Child. 132: 1195 1200.
23. Carithers, H. A. 1985. Cat-scratch disease: an overview based on a study of 1,200 patients. Am. J. Dis. Child. 139: 1124 1133.
24. Carter, A. O.,, A. A. Borczyk,, J. A. K. Carlson,, B. Harvey,, J. C. Hockin,, M. A. Karmali,, C. Krishnan,, D. A. Korn,, and H. Lior. 1987. A severe outbreak of Escherichia coli O157:H7-associated hemorrhagic colitis in a nursing home. N. Engl. J. Med. 317: 496 500.
25. Cathomas, G.,, M. Tamm,, C. Mcgandy,, A. P. Perruchoud,, M. J. Mihatsch,, and P. Dalaven. 1996. Detection of herpesvirus-like DNA in the bronchoalveolar lavage fluid of patients with pulmonary Kaposi’s sarcoma. Eur. Respir. J. 9: 1743 1746.
26. Centers for Disease Control. 1993. Outbreak of an acute illness—Southwestern United States, 1993. Morb. Mortal. Wkly. Rep. 42: 441443.
27.Centers for Disease Control and Prevention. 1996. Outbreaks of Cyclospora cayetanensis infection—United States. Morb. Mortal. Wkly. Rep. 45: 549551.
28.Centers for Disease Control and Prevention. 1996. Update: outbreaks of Cyclospora cayetanensis infection—United States. Morb. Mortal. Wkly. Rep. 45: 611612.
29. Centers for Disease Control and Prevention. 1997. Update: outbreaks of cyclosporiasis—United States and Canada, 1997. Morb. Mortal. Wkly. Rep. 46: 461462.
30.Centers for Disease Control and Prevention. 1997. Update: outbreaks of cyclosporiasis—United States. Morb. Mortal. Wkly. Rep. 46: 521523.
31.Centers for Disease Control and Prevention. 1999. Update: West Nile-like viral encephalitis—New York. Morb. Mortal. Wkly. Rep. 48: 890892.
32.Centers for Disease Control and Prevention. 1999. Update: West Nile-like viral encephalitis—New York. Morb. Mortal. Wkly. Rep. 48: 944946.
33.Centers for Disease Control and Prevention. 2000. Update: West Nile-like viral encephalitis—New York. Morb. Mortal. Wkly. Rep. 49: 100102.
34. Centers for Disease Control and Prevention. 2000. Update: West Nile Virus isolated from mosquitoes—New York, 2000. Morb. Mortal. Wkly. Rep. 49: 211.
35. Cesarman, E.,, Y. Chang,, P. Moore,, J. W. Said,, and D. M. Knowles. 1995. Kaposi’s sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based-lymphomas. N. Engl. J. Med. 332: 1186 1191.
36. Chang, Y.,, E. Cesarman,, M. Pessin,, F. Lee,, J. Culpeper,, D. M. Knowles,, and P. S. Moore. 1994. Identification of herpesvirus-like DNA sequences in AIDS associatedKaposi’s sarcoma. Science 266: 1865 1869.
37. Chapman, P. A. 1989. Evaluation of commercial latex slide test for identifying Escherichia coli O157:H7. J. Clin. Pathol. 42: 1109 1110.
38. Clarridge, J. E.,, T. J. Raich,, D. Pirwani,, B. Simon,, L. Tsai,, M. C. Rodriguez-Barradas,, R. Regnery,, A. Zollo,, D. C. Jones,, and C. Rambo. 1995. Strategy to detect and identify Bartonella species in routine clinical laboratory yields Bartonella henselae from human immunodeficiency virus-positive patient and unique Bartonella strain from his cat. J. Clin. Microbiol. 33: 2107 2113.
39. Cody, S. H.,, M. K. Glynn,, J. A. Farrar,, K. L. Cairns,, P. M. Griffin,, J. Kobayashi,, M. Fyfe,, R. Hoffman,, A. S. King,, J. H. Lewis,, B. Swaminathan,, R. G. Bryant,, and D. J. Vugia. 1999. An outbreak of Escherichia coli O157:H7 infection from unpasteurized commercial apple juice. Ann. Intern. Med. 130: 202 209.
40. Collinge, J.,, K. C. L. Sidle,, J. Meads,, J. Ironside,, and A. F. Hill. 1996. Molecular analysis of prion strain variation and the aetiology of “new variant” CJD. Nature 383: 685 690.
41. Corbellino, M.,, C. Parravicini,, J. Aubin,, and E. Berti. 1996. Kaposi’s sarcoma and herpesvirus-like DNA sequences in sensory ganglia. N. Engl. J. Med. 334: 1341 1342.
42. Dalton, M. J.,, L. E. Robinson,, J. Cooper,, R. L. Regnery,, J. G. Olsen,, and J. E. Childs. 1995. Use of Bartonella antigens for serologic diagnosis of cat-scratch disease at a national referral center. Arch. Intern. Med. 155: 1670 1676.
43. Delahoussaye, P. M.,, and B. M. Osborne. 1990. Cat-scratch disease presenting as abdominal visceral granulomas. J. Infect. Dis. 161: 71 78.
44. Dewhurst, S. 1994. Newly discovered human herpesvirus (HHV-6 and HHV-7). Curr. Opin. Infect. Dis. 7: 238 245.
45. Di Alberti, L.,, S. Ngui,, S. Porter,, P. M. Speight,, C. M. Scully,, J. M. Zakrewska,, I. G. Williams,, L. Artese,, A. Piattelli,, and C. G. Teo. 1997. Presence of human herpesvirus 8 variants in the oral tissues of human immunodeficiency virus-infected patients. J. Infect. Dis. 175: 703 707.
46. Dockrell, D. H.,, J. Prada,, M. F. Jones,, R. Patel,, A. D. Badley,, W. S. Hamsen,, D. M. Ilstrup,, R. H. Wiesner,, R. A. Kron,, T. F. Smith,, and C. V. Paya. 1997. Seroconversion to human herpesvirus 6 following liver transplantation is a marker of cytomegalovirus disease. J. Infect. Dis. 76: 1135 1140.
47. Dockrell, D. H.,, T. F. Smith,, and C. V. Paya. 1999. Human herpesvirus 6. Mayo Clin. Proc. 74: 163 170.
48. Dowell, S. F.,, R. Mukuna,, T. G. Ksiazek,, A. S. Khan,, P. E. Rollin,, and C. J. Peters. 1999. Transmission of Ebola hemorrhagic fever: a study in risk factors in family members, Kikwit Zaire 1995. J. Infect. Dis. 179( Suppl. 1): S87 S91.
49. Drancourt, M.,, J. L. Mainardi,, P. Bronqui,, F. Vandenesch,, A. Carta,, F. Lehnert,, J. Etienne,, F. Goldstein,, J. Acar,, and D. Raoult. 1995. Bartonella (Rochalimaea) quintana endocarditis in three homeless men. N. Engl. J. Med. 332: 419 423.
50. Duchin, J. S.,, F. T. Koster,, C. J. Peters,, G. L. Simpson,, B. Tempest,, S. R. Zaki,, T. G. Ksiazek,, P. E. Rollin,, S. Nichol,, E. T. Umland,, R. L. Moolenaar,, S. E. Reef,, K. B. Nolte,, M. M. Gallaher,, J. C. Butler,, and R. F. Breiman. 1994. Hantavirus pulmonary syndrome: a clinical description of 17 patients with a newly recognized disease. N. Engl. J. Med. 330: 949 955.
51. Dumler, J. S., 1999. Ehrlichia, p. 821 822. In P. R. Murray,, E. J. Baron,, M. A. Pfaller,, F. C. Tenover,, and R. H. Yolken (ed.), Manual of Clinical Microbiology, 7th ed. American Society for Microbiology, Washington, D.C..
52. Dumler, J. S.,, K. M. Asanovich,, J. S. Bakken,, P. Richter,, R. Kimsey,, and J. E. Madigan. 1995. Serologic cross-reaction among Ehrlichia equi, Ehrlichia phagocytophila, and human granulocytic ehrlichia. J. Clin. Microbiol. 33: 1098 1103.
53. Dupin, N.,, I. Gorin,, J. Deleuze,, H. Agut,, J. M. Huraux,, and J. P. Escande. 1995. Herpes-like DNA sequences, AIDS-related tumors, and Castleman’s disease. N . Engl. J. Med. 333: 798.
54. Eberhard, M. D.,, A. J. da Silva,, B. G. Lilley,, and N. J. Pieniazek. 1999. Morphologic and molecular characterization of new Cyclospora species from Ethiopian monkeys: C. cercopitheci sp. n., C. colobi sp. n., and C. papionis sp. n. Emerg. Infect. Dis. 5: 651 658.
55. Everett, E. D.,, K. A. Evans,, R. B. Henry,, and G. McDonald. 1994. Human ehrlichiosis in adults after tick exposure: diagnosis using polymerase chain reaction. Ann. Intern. Med. 120: 730 735.
56. Fishbein, D. B.,, J. E. Dawson,, and L. E. Robinson. 1994. Human ehrlichiosis in the United States, 1985-1990. Ann. Intern. Med. 20: 736 743.
57. Flaitz, C.,, Y. Jin,, M. Hicks,, C. M. Nichols,, Y. W. Yang,, and I. J. Su. 1997. Kaposi’s sarcoma-associated herpesvirus-like DNA sequences (KSHV-HHV-8) in oral AIDS-Kaposi’s sarcoma: a PCR and clinicopathologic study. Oral Surg. Oral Med. Oral Pathol. 83: 259 264.
58. Foreman, K.,, J. Friborg,, W. Kong,, C. Woffendin,, P. Polverini,, B. J. Nickoloff,, and G. J. Nabel. 1997. Propagation of a human herpesvirus from AIDS-associated Kaposi’s sarcoma. N. Engl. J. Med. 336: 163 171.
59. Formenty P.,, C. Hatz,, B. LeGuenno,, A. Stoll,, P. Rogenmoser,, and A. Widmer. 1999. Human infection due to Ebola Cote d’Ivoire: clinical and biological presentations. J. Infect. Dis. 179( Suppl. 1): S48 S53.
60. Gao, S. J.,, L. Kingsley,, M. Li,, W. Zheng,, C. Parravicini,, J. Ziegler,, R. Newton,, C. R. Rinaldo,, A. Saah,, J. Phair,, R. Detels,, Y. Chang,, and P. S. Moorel. 1996. KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi’s sarcoma. Nat. Med. 2: 925 928.
61. Garcia-Tsao, G.,, L. Panzini,, M. Toselevitz,, and A. B. West. 1992. Bacillary peliosis hepatitis as a cause of acute anemia in a patient with the acquired immunodeficiency syndrome. Gastroenterology 102: 1065 1070.
62. Gear, J. S. S.,, G. A. Cassel,, A. J. Gear,, B. Trappler,, L. Clausen,, and A. M. Meyers,, M. C. Kew,, T. H. Bothwell,, R. Sher,, G. B. Miller,, J. Schneider,, H. J. Koornhof,, E. D. Gomperts,, M. Isaacson,, and J. H. Gear. 1975. Outbreak of Marburg virus disease in Johannesburg. BMJ 4: 489 493.
63. Georges, A.,, E. B. Leroy,, A. A. Renout,, C. T. Benissan,, R. J. Nabias,, M. T. Ngoc,, P. I. Obiang,, J. P. M. LePage,, E. J. Bertherat,, D. D. Benoni,, E. J. Wickings,, J. P. Amblard,, J. M. Lansound-Soukate,, J. M. Milleliri,, S. Bize,, and M. C. Georges-Courbot. 1999. Recent Ebola outbreaks in Gabon from 1994 to 1997: epidemiologic and health control issues. J. Infect. Dis. 179( Suppl. 1): S65 S75.
64.Reference deleted.
65. Goral, S.,, B. Anderson,, C. Hager,, and K. M. Edwards. 1994. Detection of Rochalimaea henselae DNA by polymerase chain reaction from suppurative nodes of children with cat scratch disease. Pediatr. Infect. Dis. J. 13: 994 997.
66. Griffin, P. M., 1995. Escherichia coli O157:H7 and other enterohemorrhagic Escherichia coli, p. 739 761. In M. J. Blaser,, P. D. Smith,, J. I. Ravdin,, H. B. Greenberg,, and R. L. Guerrant (ed.), Infections of the Gastrointestinal Tract. Raven Press, Ltd., New York, N.Y..
67. Griffin, P. M.,, S. M. Ostroff,, R. V. Tauxe,, K. D. Greene,, J. G. Wells,, J. H. Lewis,, and P. A. Blake. 1988. Illnesses associated with Escherichia coli O157:H7 infections: a broad clinical spectrum. Ann. Intern. Med. 109: 705 712.
68. Hall, C. B.,, C. E. Long,, K. C. Schnabel,, M. T. Caserta,, K. M. McIntyre,, M. A. Costanzo,, A. Knott,, S. Dewhurst,, R. A. Insel,, and L. G. Epstein. 1994. Human herpesvirus-6 infection in children: a prospective study of complications and reactivation. N. Engl. J. Med. 331: 432 438.
69. Hallin, G. W.,, S. Q. Simpson,, R. E. Crowell,, D. S. James,, F. T. Koster,, G. J. Merz,, and H. Levy. 1996. Cardiopulmonary manifestations of the hantavirus pulmonary syndrome. Crit. Care Med. 24: 252 258.
70. Herbein, G.,, J. Strasswimmer,, M. Altieri,, M. L. Woehl-Jaegle,, P. Wolf,, and G. Obert. 1996. Longitudinal study of human herpesvirus 6 infection in organ transplant recipients. Clin. Infect. Dis. 22: 171 173.
71. Herwaldt, B. L.,, M. L. Ackers, and the Cyclospora Working Group. 1997. An outbreak in 1996 of cyclosporins associated with imported raspberries. N. Engl. J. Med. 336: 1548 1556.
72. Hjelle, B.,, S. Jenison,, G. Mertz,, F. Koster,, and K. Fovear. 1994. Emergence of hantavirus disease in the southwestern United States. West J. Med. 161: 467 473.
73. Hmiel, S. P.,, R. Buller,, M. Arens,, M. Gaudreault-Keener,, and G. A. Storch. 1998. Human infection with Ehrlichia ewingii, the agent of Ozark canine granulocytic ehrlichiosis. Proceedings of the First International Conference on Emerging Infectious Diseases. Addendum 4.
74. Hoge, C. W.,, P. Echeverria,, R. Rajah,, J. Jacobs,, S. Malthouse,, E. Chapman,, L. M. Jimenez,, and D. R. Shlim. 1995. Prevalence of Cyclospora species and other enteric pathogens among children less than 5 years of age in Nepal. J. Clin. Microbiol. 33: 3058 3060.
75. Hoge, C. W.,, D. R. Shlim,, M. Ghimire,, J. G. Rabold,, P. Pandey,, A. Walch,, R. Rajah,, P. Gaudio,, and P. Echeverria. 1995. Placebo-controlled trial of co-trimoxazole for cyclospora infections among travellers and foreign residents in Nepal. Lancet 345: 691 693.
76. Holmes, A. H.,, T. C. Greenough,, G. J. Balady,, R. Regnery,, B. Anderson,, J. C. O’Keane,, J. Fonger,, and E. McCrone. 1995. Bartonella henselae endocarditis in an immunocompetent adult. Clin. Infect. Dis. 21: 1004 1007.
77. Huang, P.,, J. T. Weber,, D. M. Sosin,, P. M. Griffin,, E. G. Long,, J. J. Murphy,, F. Kocka,, C. Peters,, and C. Kallick. 1995. The first reported outbreak of diarrheal illness associated with Cyclospora in the United States. Ann. Intern. Med. 123: 409 414.
78. Jacobs, U.,, J. Ferber,, and H. U. Klehr. 1994. Severe allograft dysfunction after OKT3-induced human herpesvirus-6 reactivation. Transplant. Proc. 26: 3121.
79. Jalava, J.,, P. Kotilainen,, S. Nikkari,, M. Skurnik,, E. Vanttinen,, O.-P. Lehtonen,, E. Eerola,, and P. Toivanen. 1995. Use of the polymerase chain reaction and DNA sequencing for detection of Bartonella quintana in the aortic valve of a patient with culture-negative infective endocarditis. Clin. Infect. Dis. 21: 891 896.
80. Johnson, W. T.,, and E. B. Helwig. 1969. Cat-scratch disease (histopathologic changes in the skin). Arch. Dermatol. 100: 148 154.
81. Jongejan, F.,, L. A. Wassink,, M. J. C. Thielemans,, N. M. Perie,, and G. Uilenberg. 1989. Serotypes in Cowdria ruminantium and their relationship with Ehrlichia phagocytophila determined by immunofluorescence. Vet. Microbiol. 21: 31 40.
82. Karmali, M. A.,, M. Petric,, C. Lim,, P. C. Fleming,, G. S. Arbus,, and H. Lior. 1985. The association between idiopathic hemolytic-uremic syndrome and infection by verotoxin-producing Escherichia coli. J. Infect. Dis. 151: 77 82.
83. Karmali, M. A.,, B. T. Steele,, M. Petric,, and C. Lim. 1983. Sporadic cases of haemolytic-uraemic syndrome associated with faecal cytotoxin and cytotoxin-producing Escherichia coli in stools. Lancet. i: 619 620.
84. Kedes, D.,, D. Ganem,, N. Ameli,, P. Bacchetti,, and R. Greenblatt. 1997. The prevalence of serum antibody to human herpesvirus 8 (Kaposi’s sarcoma-associated herpesvirus) among HIV-seropositive and high-risk HIV-seronegative women. JAMA 277: 478 481.
85. Kedes, D.,, E. Operskalski,, M. Busch,, R. Kohn,, J. Flood,, and D. Ganem. 1996. The seroepidemiology of human herpesvirus 8 (Kaposi’s sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission. Nat. Med. 2: 918 924.
86. Keene, W. E.,, J. M. McAnulty,, F. C. Hoesly,, L. P. Williams,, K. Hedberg,, G. L. Oxman,, T. J. Barrett,, M. A. Pfaller,, and D. W. Fleming. 1994. A swimming-associated outbreak of hemorrhagic colitis caused by Escherichia coli O157:H7 and Shigella sonnei. N. Engl. J. Med. 331: 579 584.
87. Keene, W. E.,, E. Sazie,, J. Kok,, D. H. Rice,, D. D. Hancock,, V. K. Balan,, T. Zhao,, and M. P. Doyle. 1997. An outbreak of Escherichia coli O157:H7 infections traced to jerky made from deer meat. JAMA 277: 1229 1231.
88. Kemper, C. A.,, C. M. Lombard,, S. C. Deresinsksi,, and L. S. Tompkins. 1990. Visceral bacillary epitheliod angiomatosis: possible manifestations of disseminated cat-scratch disease in the immunocompromised host. A report of two cases. Am. J. Med. 89: 216 222.
89. Khan, A.,, T. F. Keweteminga,, D. H. Heymann,, B. LeGuenno,, P. Nabeth,, B. Kerstiens,, Y. Fleerackers,, P. H. Kilmarx,, G. R. Rodier,, O. Nkuku,, P. E. Rollin,, A. Sanchez,, S. R. Zaki,, R. Swanepoel,, O. Tomori,, S. T. Nichol,, C. J. Peters,, J. J. Muyembe-Tamfun,, and T. G. Ksiazek. 1999. The re-emergence of Ebola hemorrhagic fever (EHF) Zaire, 1995. J. Infect. Dis. 179( Suppl. 1): S76 S86.
90. Khan, A.,, R. F. Khabbaz,, L. R. Armstrong,, R. C. Holman,, S. P. Bauer,, J. Graber,, T. Strine,, G. Miller,, S. Reef,, J. Tappero,, P. E. Rolin,, S. T. Nichol,, S. R. Zaki,, R. T. Bryan,, L. E. Chapman,, C. J. Peters,, and T. G. Ksiazek. 1996. Hantavirus pulmonary syndrome: the first 100 U.S. cases. J. Infect. Dis. 173: 1297 1303.
91. Klein, M. D.,, C. M. Nelson,, and J. L. Goodman. 1997. Antibiotic susceptibility of the newly cultivated agent of human granulocytic ehrlichiosis: promising activity of quinolones and rifamycins. Antimicrob. Agents Chemother. 41: 76 79.
92. Knox, K. K.,, and D. R. Carrigan. 1995. Active human herpesvirus (HHV-6) infection of the central nervous system in patients with AIDS. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 9: 69 73.
93. Koehler, J. E.,, F. D. Quinn,, T. G. Berger,, P. E. LeBoit,, and J. W. Tappero. 1992. Isolation of Rochalimaea species from cutaneous and osseous lesions of bacillary angiomatosis. N. Engl. J. Med. 327: 1625 1631.
94. Koehler, J. E.,, and J. W. Tappero. 1993. Bacillary angiomatosis and bacillary peliosis in patients infected with the human immunodeficiency virus. Clin. Infect. Dis. 17: 612 624.
95. Koster, F. T.,, and S. Jenison,. 1997. The hantavirus. In S. L. Gorbach,, J. G. Bartlett,, and N. R. Blacklow (ed.), Infectious Diseases, 2nd ed. W. B. Saunders, Philadelphia, Pa..
96. Kudva, I. T.,, P. G. Hatfield,, and C. J. Hovde. 1996. Escherichia coli O157:H7 in microbial flora of sheep. J. Clin. Microbiol. 34: 431 433.
97. Larson, A. M.,, M. J. Dougherty,, D. J. Nowowiejski,, D. F. Welch,, G. M. Matar,, B. Swaminathan,, and M. B. Coyle. 1994. Detection of Bartonella (Rochalimaea) quintana by routine acridine orange staining of broth blood cultures. J. Clin. Microbiol. 32: 1492 1496.
98. La Scola, B.,, and D. Raoult. 1996. Serologic cross-reactions between Bartonella quintana, Bartonella henselae, and Coxiella burnetii. J. Clin. Microbiol. 34: 2270 2274.
99. Lawson, P. A.,, and M. D. Collins. 1996. Description of Bartonella clarridgeiae sp. nov. isolated from the cat of a patient with Bartonella henselae septicemia. Med. Microbiol. Lett. 5: 64 73.
100. Le, H. H.,, D. A. Palay,, B. Anderson,, and J. P. Steinberg. 1994. Conjunctival swab to diagnose ocular cat scratch disease. Am. J. Ophthalmol. 118: 249 250.
101. LeBoit, P. E.,, T. G. Berger,, B. M. Egbert,, J. H. Beckstead,, T. S. Yen,, and M. H. Stoler. 1989. Bacillary angiomatosis: the histopathology and differential diagnosis of a pseudoneoplastic infection in patients with human immunodeficiency virus disease. Am. J. Surg. Pathol. 13: 909 920.
102. LeBoit, P. E.,, T. G. Berger,, B. M. Egbert,, S. B. Yen,, M. H. Stoler,, T. A. Bonfiglio,, J. A. Strauchen,, C. K. English,, and D. J. Wear. 1988. Epitheliod hemangioma-like vascular proliferation in AIDS: manifestation of cat-scratch disease bacillus infection. Lancet i: 960 963.
103. Lennette, E.,, D. Blackbourn,, and J. Levy. 1996. Antibodies to human herpesvirus type 8 in the general population and in Kaposi’s sarcoma patients. Lancet 348: 858 861.
104. Lenoir, A. A.,, G. A. Storch,, K. Deschryver-Kecskemeti,, G. S. Shackleford,, R. J. Rothbaum,, D. J. Wear,, and J. L. Rosenblum. 1988. Granulomatous hepatitis associated with cat-scratch disease. Lancet i: 1132 1136.
105. Le Saux, N.,, J. S. Spika,, B. Friesen,, I. Johnson,, D. Melnychuck,, C. Anderson,, R. Dion,, M. Rahman,, and W. Tostowaryk. 1993. Ground beef consumption in noncommercial settings is a risk factor for sporadic Escherichia coli O157:H7 infection in Canada. J. Infect. Dis. 167: 500 501.
106. Lin, J.-C.,, S.-C. Lin,, E.-C. Mar,, P. E. Pellett,, F. R. Stamey,, J. A. Stewart,, and T. J. Spira. 1995. Is Kaposi’s sarcoma-associated herpesvirus detectable in semen of HIV-infected homosexual men? Lancet 346: 1601 1602.
107. Long, E. G.,, E. H. White,, W. W. Carmichael,, P. M. Quinlisk,, R. Raja,, B. L. Swisher,, H. Daugharty,, and M. T. Cohen. 1991. Morphologic and staining characteristics of a cyanobacterium-like organism associated with diarrhea. J. Infect. Dis. 164: 199 202.
108. Low, D. E.,, E. Liu,, J. Fuller,, and A. McGeer,. 1999. Streptococcus iniae: an emerging pathogen in the aquaculture industry, p. 53 65. In W. M. Scheld,, W. A. Craig,, and J. M. Hughes (ed.), Emerging Infections 3. American Society for Microbiology, Washington, D.C..
109. MacDonald, K. L.,, M. J. O. Leary,, M. L. Cohen,, P. Norris,, J. G. Wells,, E. Noll,, J. M. Kobayashi,, and P. A. Blake. 1988. Escherichia coli O157:H7, an emerging gastrointestinal pathogen: results of a one-year, prospective, population-based study. JAMA 259: 3567 3570.
110. MacLeod, J. R.,, and W. S. Gordon. 1993. Studies in tick-borne fever of sheep. Transmission by the tick, Ixodes ricinus, with a description of the disease produced. Parasitology 25: 273 285.
111. Madico, G.,, J. McDonald,, R. H. Gilman,, L. Cabrera,, and C. R. Sterling. 1997. Epidemiology and treatment of Cyclospora cayetanensis infection in Peruvian children. Clin. Infect. Dis. 24: 977 981.
112. Malatack, J. J.,, and R. Jaffe. 1993. Granulomatous hepatitis in three children due to cat-scratch disease without peripheral adenopathy. Am. J. Dis. Child. 147: 949 953.
113. March, S. B.,, and S. Ratnam. 1986. Sorbitol-MacConkey medium for detection of Escherichia coli O157:H7 associated with hemorrhagic colitis. J. Clin. Microbiol. 23: 869 872.
114. March, S. B.,, and S. Ratnam. 1989. Latex agglutination test for detection of Escherichia coli serotype O157. J. Clin. Microbiol. 27: 1675 1677.
115. Margileth, A. M. 1993. Cat-scratch disease. Adv. Pediatr. Infect. Dis. 8: 1 21.
116. Margileth, A. M.,, D. J. Wear,, T. L. Hadfield,, C. J. Schlagel,, G. T. Spigel,, and J. E. Muhlbauer. 1984. Cat-scratch disease: bacteria in skin at the primary inoculation site. JAMA 252: 928 931.
117. Marra, C. M. 1995. Neurologic complications of Bartonella henselae infection. Curr. Opin. Neurol. 8: 164 169.
118. Martini, G. A.,, and R. Siegert (ed.). 1971. Marburg Virus Disease, p. 1 230. Springer-Verlag, Berlin, Germany.
119. Maurin, M.,, V. Roux,, S. Stein,, F. Ferrier,, R. Viraben,, and D. Raoult. 1994. Isolation and characterization by imunofluorescence, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Western Blot, restriction fragment length polymorphism PCR, 16S rRNA gene sequencing, and pulsed-field gel electrophoresis of Rochalimaea quintana from a patient with bacillary angiomatosis. J. Clin. Microbiol. 32: 1166 1171.
120. McDonough, P. L.,, C. A. Rossiter,, R. B. Rebhun,, S. M. Stehman,, D. H. Lein,, and S. J. Shin. 2000. Prevalence of Escherichia coli O157:H7 from cull dairy cows in New York state and comparison of culture methods used during preharvest food safety investigations. J. Clin. Microbiol. 38: 318 322.
121. McIntosh, B. M.,, P. G. Jupp,, I. DosSantos,, and G. M. Meenehan. 1976. Epidemics of West Nile and Sindbis viruses in South Africa with Culex (Culex) univittatus Theibald as a vector. S. Afr. J. Sci. 72: 295 300.
122. Mertz, G. J.,, B. Hjelle,, and R. T. Bryon. 1998. Hantavirus infection. Disease-a-Month 44(3): 85 138.
123. Miller, G.,, M. O. Rigsby,, L. Heston,, E. Grogan,, R. Sun,, C. Metroka,, J. A. Levy,, S. J. Gao,, Y. Chang,, and P. Moore. 1996. Antibodies to butyrate-inducible antigens of Kaposi’s sarcoma-associated herpesvirus in patients with HIV-1 infection. N. Engl. J. Med. 334: 1292 1297.
124. Monini, P.,, L. de Lellis,, M. Fabris,, F. Rigolin,, and E. Cassai. 1996. Kaposi’s sarcoma associated herpesvirus DNA sequences in prostate tissue and human semen. N. Engl. J. Med. 334: 1168 1172.
125. Moolenaar, R. L.,, C. Dalton,, H. B. Lipman,, E. T. Umland,, M. Gallaher,, J. S. Duehn,, L. Chapman,, S. R. Zaki,, T. G. Ksiazek,, and P. E. Rollin. 1995. Clinical features that differentiate hantavirus pulmonary syndrome from three other acute respiratory illness. Clin. Infect. Dis. 21: 643 649.
126. Moore, P.,, C. Boshoff,, R. Weiss,, and Y. Chang. 1996. Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science 274: 1739 1744.
127. Myers, S. A.,, N. S. Prose,, J. A. Garcia,, K. H. Wilson,, K. P. Dunsmore,, and H. Kamino. 1992. Bacillary angiomatosis in a child undergoing chemotherapy. J. Pediatr. 121: 574 578.
128. Nathanson, N.,, J. Wilesmith,, and C. Griot. 1997. Bovine sponjpgorm encephalopathy (BSE): causes and consequences of a common source epidemic. Am. J. Epidemiol. 145: 959 969.
129. Noah, D. L.,, J. S. Bresee,, M. J. Gorenseck,, J. A. Rooney,, J. L. Cresanta,, R. L. Regnery,, J. Wong,, J. DelToro,, J. G. Olson,, and J. F. Childs. 1995. Cluster of five children with acute encephalopathy associated with cat-scratch disease in south Florida. Pediatr. Infect. Dis. J. 14: 866 869.
130. Noda, M.,, T. Yutsudo,, N. Nakabayashi,, T. Hirayama,, and Y. Takeda. 1987. Purification and some properties of Shiga-like toxin from Escherichia coli O157:H7 that is immunologically identical to Shiga toxin. Microb. Pathog. 2: 339 349.
131. Okuno, T.,, K. Higashi,, K. Shiraki,, K. Yamanishi,, M. Takahashi,, Y. Kokado,, M. Ishibashi,, S. Takahara,, T. Sonoda,, and K. Tanaka. Human herpesvirus 6 infection in renal transplantation. Transplantation 49: 519 522.
132. Oren, I.,, and J. D. Sobel. 1992. Human herpesvirus 6: review. Clin. Infect. Dis. 14: 741 746.
133. Ortega, Y. R.,, C. R. Sterling,, R. H. Gilman,, V. A. Cama,, and F. Diaz. 1993. Cyclospora species—a new protozoan pathogen of humans. N. Engl. J. Med. 328: 1308 1312.
134. Ostroff, S. M.,, J. M. Kobayashi,, and J. H. Lewis. 1989. Infections with Escherichia coli O157:H7 in Washington State. The first year of statewide disease surveillance. JAMA 262: 355 359.
135. Padhye, V. V.,, F. B. Kittell,, and M. P. Doyle. 1986. Purification and physicochemical properties of a unique Vero cell cytotoxin from Escherichia coli O157:H7. Biochem. Biophys. Res. Commun. 139: 424 430.
136. Pape, J. W.,, R. I. Verdier,, M. Boncy,, J. Boncy,, and W. D. Johnson, Jr. 1994. Cyclospora infection in adults infected with HIV. Clinical manifestations, treatment, and prophylaxis. Ann. Intern. Med. 121: 654 657.
137. Park, C. H.,, D. L. Hixon,, W. L. Morrison,, and C. B. Cook. 1994. Rapid diagnosis of enterohemorrhagic Escherichia coli O157:H7 directly from fecal specimens using immunofluorescence stain. Am. J. Clin. Pathol. 101: 91 94.
138. Park, C. H.,, N. M. Vandel,, and D. L. Hixon. 1996. Rapid immunoassay for detection of Escherichia coli O157:H7 directly from stool specimens. J. Clin. Microbiol. 34: 988 990.
139. Perkocha, L. A.,, S. M. Geaghan,, T. S. B. Yen,, S. L. Nishimura,, S. P. Chan,, R. Garcia-Kennedy,, G. Honda,, A. C. Stoloff,, H. Z. Klein,, R. L. Goldman,, S. VanMeter,, L. D. Ferrel,, and P. E. LeBoit. 1990. Clinical and pathological features of bacillary peliosis hepatitis in association with human immunodeficiency virus infection. N. Engl. J. Med. 323: 1581 1586.
140. Peters, C. J., 2000. California encephalitis, hantavirus pulmonary syndrome, and bunyaviridae hemorrhagic fevers, p. 1849 1855. In G. L. Mandell,, J. E. Bennett,, and R. Dolin (ed.) Principles and Practice of Infectious Diseases, 5th ed. Churchill Livingstone, Philadelphia, Pa..
141. Peters, C. J., 2000. Marburg and ebola virus hemorrhagic fevers, p. 1821 1823. In G. L. Mandell,, J. E. Bennett,, and R. Dolin (ed.), Principles and Practice of Infectious Diseases, 5th ed., Churchill Livingstone, Philadelphia, Pa..
142. Peters, C. J.,, E. D. Johnson,, and P. B. Jahrling. 1991. Filoviruses, p. 159 175. In S. Morse (ed.), Emerging Viruses. Oxford University Press, New York, N.Y..
143. Peters, C. J.,, and J. W. LeDuc (ed.). 1999. Ebola: the virus and the disease. J. Infect. Dis. 179( Suppl. 1): S1 S288.
144. Peters, D.,, J. A. Sanchez,, and P. E. Rollin,. 1999. Filoviridae: Marburg and Ebola viruses, p. 1161 1176. In B. N. Fields, and D. N. Knipe (ed.), Virology, 3rd ed. Raven, New York, N.Y..
145. Pier, G. B.,, and S. H. Madin. 1976. Streptococcus iniae sp. nov., a beta-hemolytic streptococcus isolated from an Amazon freshwater dolphin, Inia geoffrensis. Int. J. Syst. Bacteriol. 26: 545 553.
146. Pruksanamonda, P.,, C. B. Hall,, R. A. Insel,, K. M. McIntyre,, P. E. Pellet,, C. E. Long,, K. Schnabel,, P. H. Pincus,, F. R. Stamey,, and T. R. Dambaugh. 1990. Primary human herpesvirus-6 infection in young children. N. Engl. J. Med. 326: 1445 1450.
147. Raoult, D.,, P. E. Fournier,, M. Drancourt,, T. J. Marrie,, J. Etienne,, J. Cosserat,, P. Cacoub,, Y. Poinsignon,, P. Leclerg,, and A. M. Sefton. 1996. Diagnosis of 22 new cases of Bartonella endocarditis. Ann. Intern. Med. 125: 646 652.
148. Regnery, R.,, J. G. Olson,, B. A. Perkins,, and W. Bibb. 1992. Serological response to “Rochalimaea henselae” antigen in suspected cat-scratch disease. Lancet 339: 1443 1445.
149. Regnery, R.,, and J. Tappero. 1995. Unraveling mysteries associated with cat-scratch disease, bacillary angiomatosis, and related syndromes. Emerg. Infect. Dis. 1: 16 21.
150. Regnery, R. L.,, B. E. Anderson,, J. E. Clarridge III,, M. Rodriguez-Barradas,, D. C. Jones,, and J. H. Carr. 1992. Characterization of a novel Rochalimaea species, R. henselae sp. nov., isolated from the blood of a febrile, human immunodeficiency virus-positive patient. J. Clin. Microbiol. 30: 265 274.
151. Relman, D. A. 1993. The identification of uncultured microbial pathogens. J. Infect. Dis. 168: 1 8.
152. Relman, D. A., 1998. Cyclospora: whence and where to?, p. 185 194. In W. M. Scheld,, W. A. Craig,, and J. M. Hughes (ed.). Emerging Infections 2. American Society for Microbiology, Washington, D.C..
153. Relman, D. A.,, J. S. Loutit,, T. M. Schmidt,, S. Falkow,, and L. S. Tompkins. 1990. The agent of bacillary angiomatosis: an approach to the identification of uncultured pathogens. N. Engl. J. Med. 23: 1573 1580.
154. Relman, D. A.,, T. M. Schmidt,, A. Gajadhar,, M. Sogin,, J. Cross,, K. Yoder,, O. Sethabutr,, and P. Echeverria. 1996. Molecular phylogenetic anlaysis of Cyclospora, the human intestinal pathogens, suggests that it is closely related to Eimeria species. J. Infect. Dis. 173: 440 445.
155. Rickter, P. J.,, R. B. Kimsey,, J. E. Madigan,, J. E. Barlough,, J. S. Dumler,, and D. L. Brooks. 1996. Ixodes pacificus as a vector of Ehrlichia equi. J. Med. Entomol. 33: 1 5.
156. Riley, L. W.,, R. S. Remis,, S. D. Helgerson,, H. B. McGee,, J. G. Wells,, B. R. Davis,, R. J. Hebert,, E. S. Olcott,, L. M. Johnson,, N. T. Hargrett,, P. A. Blake,, and M. L. Cohen. 1983. Hemorrhagic colitis associated with a rare Escherichia coli serotype. N. Engl. J. Med. 308: 681 685.
157. Robinson, S. W. 1994. Human herpesvirus 6. Curr. Clin. Top. Infect. Dis. 14: 159 169.
158. Rollin, P. E.,, J. Williams,, D. Bressler,, S. Pearson,, M. Cottingham,, G. Pucak,, A. Sanchez,, S. G. Trappier,, R. L. Peters,, P. W. Greer,, S. Zaki,, T. Demarcus,, K. Kelley,, D. Simpson,, T. W. Geisbert,, P. B. Jahrlina,, C. J. Peters,, and T. G. Ksiazek. 1999. Ebola (subtype Reston) virus among quarantined non-human primates recently imported from the Philippines to the United States . J. Infect. Dis. 179( Suppl. 1): S108 S114.V
159. Ruoff, K. L.,, R. A. Whiley,, and D. Beighton,. 1999. Streptococcus, p. 285 286. In P. R. Murray,, E. J. Baron,, M. A. Pfaller,, F. C. Tenover,, and R. H. Yolken (ed.), Manual of Clinical Microbiology, 7th ed. American Society for Microbiology, Washington, D.C..
160. Salahuddin, S. Z.,, D. V. Ablashi,, P. D. Markham,, S. F. Josephs,, S. Sturzengger,, M. Kaplan,, G. Halligan,, P. Biberfield,, F. Wong-Staal,, and B. Kramarsky. 1986. Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders. Science 234: 596 601.
161. Sanchez, A.,, S. G. Trappier,, B. W. J. Mahy,, C. J. Peters,, and S. T. Nichol. 1996. The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing. Proc. Natl. Acad. Sci. USA 93: 3602 3607.
162. Sanchez, A.,, S. G. Trappier,, U. Stroker ,, S. T. Nichol,, M. D. Bowen,, and H. Feldmann. 1998. Variation in the glycoprotein and VP35 genes of Marburg virus strains. Virology 240: 138 146.
163. Schlossberg, D.,, Y. Morad,, T. B. Krouse,, D. J. Wear,, C. K. English,, and M. Littman. 1989. Culture proved disseminated cat scratch disease in acquired immunodeficiency syndrome. Arch. Intern. Med. 149: 1437 1439.
164. Schonberger, L. B. 1998. New variant Creutzfeldt-Jacob disease and bovine sponjpgorm encephalopathy. Infect. Dis. Clin. N. Am. 12: 111 121.
165. Secchiero, P.,, D. Zella,, R. W. Crowley,, R. C. Gallo,, and P. Lusso. 1995. Quantitative PCR for human herpesvirus 6 and 7. J. Clin. Microbiol. 33: 2124 2130.
166. Shukla, R.,, R. Slack,, R. George,, T. Cheasty,, B. Rowe,, and J. Scutter. 1995. Escherichia coli O157:H7 infection associated with a farm visitor centre. Commun. Dis. Rep. CDR Rev. 5: R86 90.
167. Simpson, S. Q. 1998. Hantavirus pulmonary syndrome. Heart Lung 27: 51 57.
168. Singh, N.,, and D. R. Carrigan. 1996. Human herpesvirus 6 in transplantation: an emerging pathogen. Ann. Intern. Med. 124: 1065 1071.
169. Slater, L. N.,, D. F. Welch,, D. Hensel,, and D. W. Coody. 1990. A newly recognized fastidious gram-negative pathogen as a cause of fever and bacteremia. N. Engl. J. Med. 23: 1587 1593.
170. Slater, L. N.,, D. F. Welch,, and K.-W. Min. 1992. Rochalimaea henselae causes bacillary angiomatosis and peliosis hepatitis. Arch. Intern. Med. 152: 602 606.
171. Slutsker, L.,, A. A. Ries,, K. D. Greene,, J. G. Wells,, L. Hutwagner,, and P. M. Griffin for The Escherichia coli O157:H7 Study Group. 1997. Escherichia coli O157:H7 diarrhea in the United States: clinical and epidemiologic features. Ann. Intern. Med. 126: 505 513.
172. Smith, M.,, C. Bloomer,, R. Horvat,, E. Goldstein,, J. M. Casparian,, and B. Chandran. 1997. Detection of human herpesvirus 8 DNA in Kaposi’s sarcoma lesions and peripheral blood of human immunodeficiency virus-positive patients and correlation with serologic measurements. J. Infect. Dis. 176: 84 93.
173. Smith, R. D.,, D. M. Sells,, E. H. Stephenson,, M. Ristic,, and D. L. Huxsoll. 1997. Development of Ehrlichia canis, causative agent of canine ehrlichiosis, in the tick Rhipicephalus sanguineus and its differentiation from a symbiotic rickettsia. Am. J. Vet. Res. 37: 119 126.
174. Smithburn, K. C.,, T. P. Hughes,, A. W. Burke,, and J. H. Paul. 1940. A neurotropic virus isolated from the blood of a native of Uganda. Am. J. Trop. Med. Hyg. 20: 471 492.
175. Spach, D. H.,, A. S. Kanter,, N. A. Daniels,, D. J. Nowowiejski,, A. M. Larson,, R. A. Schmidt,, B. Swaminathan,, and D. J. Brenner. 1995. Bartonella (Rochalimaea) species as a cause of apparent “culture-negative” endocarditis. Clin. Infect. Dis. 20: 1044 1047.
176. Spach, D. H.,, and J. E. Koehler. 1998. Bartonellaassociated infections. Infect. Dis. Clin. N. Am. 12: 137 155.
177. Steeper, T. A.,, H. Rosentine,, J. Weiser,, S. Inampudi,, and D. C. Snover. 1992. Bacillary epitheloid angiomatosis involving the liver, spleen and skin in AIDS patients with concurrent Kaposi’s sarcoma. Am. J. Clin. Pathol. 97: 713 718.
178. Stoler, M. H.,, T. A. Bonfiglio,, R. T. Steigbigel,, and M. Pereira. 1983. An atypical subcutaneous infection associated with the acquired immunodeficiency syndrome. Am. J. Clin. Pathol. 80: 714 718.
179. Straus, S. E., 2000. Human herpesvirus types 6 and 7, p. 1613 1616. In G. L. Mandell,, J. E. Bennett,, and R. Dolin (ed.), Principles and Practice of Infectious Diseases. Churchill Livingstone, Philadelphia, Pa..
180. Strockbine, N. A.,, L. R. Marques,, J. W. Newland,, H. W. Smith,, R. K. Holmes,, and A. D. O’Brien. 1986. Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities. Infect. Immun. 53: 135 140.
181. Su, C.,, and L. J. Brandt. 1995. Escherichia coli O157:H7 infection in humans. Ann. Intern. Med. 123: 698 714.
182. Swerdlow, D. L.,, B. A. Woodruff,, R. C. Brady,, P. M. Griffin,, S. Tippen,, H. D. Donnell,, E. Geldreich,, B. J. Payne,, A. Meyer,, J. G. Wells,, K. D. Greene,, M. Bright,, N. H. Bean,, and P. A. Blake. 1992. A waterborne outbreak in Missouri of Escherichia coli O157:H7 associated with bloody diarrhea and death. Ann. Intern. Med. 117: 812 819.
183. Takasaki, T.,, N. Ohkana,, K. Sano,, S. Morimatsu,, T. Nakano,, M. Nakai,, J. Yamaguchi,, and I. Kurane. 1997. Electron microscopic study of human herpesvirus 6 infected human T-cell lines superinfected with human immunodeficiency virus type 1. J. Acta Virol. 41: 221 229.
184. Tang, Y. W.,, M. J. Espy,, D. H. Persing,, and T. F. Smith. 1997. Molecular evidence and clinical significance of herpesvirus 6 infection in the central nervous system. J. Clin. Microbiol. 35: 2869 2872.
185. Tappero, J. W.,, J. E. Koehler,, T. G. Berger,, C. J. Cockerell,, T.-H. Lee,, M. P. Busch,, D. P. Sites,, J. Mohle-Boetan,, A. L. Reingold,, and P. E. LeBoit. 1993. Bacillary angiomatosis and bacillary splenitis in immunocompetent adults. Ann. Intern. Med. 118: 363 365.
186. Tarr, P. I.,, M. A. Neill,, C. R. Clausen,, S. L. Watkins,, D. L. Christie,, and R. O. Hickman. 1990. Escherichia coli O157:H7 and the hemolytic-uremic syndrome: importance of early cultures in establishing the etiology. J. Infect. Dis. 162: 553 556.
187. Telford, S. R., III, J. E. Dawson, P. Katavolos, C. K. Warner, C. P. Kolbert, and D. H. Persing. 1996. Perpetuation of the agent of human granulocytic ehrlichiosis in a deer tick-rodent cycle. Proc. Natl. Acad. Sci.USA 93: 6209 6214.
188. Tison, D. L. 1990. Culture confirmation of Escherichia coli serotype O157:H7 by direct immunofluorescence. J. Clin. Microbiol. 28: 612 613.
189. Torok, L.,, S. Z. Viragh,, I. Borka,, and M. Tapai. 1994. Bacillary angiomatosis in a patient with lymphocytic leukemia. Br. J. Dermatol. 130: 665 668.
190. Trevena, W. B.,, R. S. Hooper,, C. Wray,, G. A. Willshaw,, T. Cheasty,, and G. Domingue. 1996. Verocytotoxin-producing Escherichia coli O157:H7 associated with companion animals. Vet. Rec. 138: 400.
191. Visvesvara, G. S.,, H. Moura,, E. Kovacs-Nace,, S. Wallace,, and M. L. Eberhard. 1997. Uniform staining of Cyclospora oocysts in fecal smears by a modified safranin technique with microwave heating. J. Clin. Microbiol. 35: 730 733.
192. Vitek, C. R.,, R. F. Breiman,, T. G. Ksiazek,, P. E. Rollin,, J. C. McLaughlin,, E. T. Umland,, K. B. Nolte,, A. Loera,, C. M. Sewell,, and C. J. Peters. 1996. Evidence against person-to-person transmission of hantavirus to health care workers. Clin. Infect. Dis. 22: 824 826.
193. Walker, D. H., 1998. Emerging human ehrlichioses: recently recognized, widely distributed, life-threatening tick-borne diseases, p. 81 91. In W. M. Scheld,, D. Armstrong,, and J. M. Hughes (ed.), Emerging Infections 1. American Society for Microbiology, Washington, D.C..
194. Walker, D. H.,, and J. S. Dumler. 1996. Emergence of ehrlichioses as human health problems. Emerg. Infect. Dis. 2: 18 29.
195. Walker, D. H.,, and J. S. Dumler. 1997. Human monocytic and granulocytic ehrlichioses. Discovery and diagnosis of emerging tick-borne infections and the critical role of the pathologist. Arch. Pathol Lab. Med. 121: 785 791.
196. Walker, D. H.,, and J. S. Dumler,. 2000. Ehrlichia chaffeensis (human mococytotropic ehrlichiosis), Ehrlichia phagocytophila (human granulocytotropic ehrlichiosis), and other ehrlichiae, p. 2057 2064. In G. L. Mandell,, J. E. Bennett,, and R. Dolin (ed.), Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 5th ed. Churchill Livingstone, Philadelphia, Pa..
197. Ward, K. N.,, J. J. Gray,, and S. Efstathiou. 1989. Brief report: primary human herpesvirus 6 infection in a patient following liver transplantation from a seropositive donor. J. Med. Virol. 28: 69 72.
198. Wear, D. J.,, A. M. Margileth,, T. L. Hadfield,, and G. W. Fischer,, C. J. Schlagel,, and F. M. King. 1983. Cat-scratch disease:a bacterial infection. Science 221: 1403 1404.
199. Weinstein, M. R.,, M. Litt,, D. A. Kertesz,, P. Wyper,, D. Rose,, M. Coulter,, A. McGeer,, R. Facklam,, C. Ostach,, B. M. Willey,, A. Borczyk,, D. E. Low, and The S. iniae Study Group. 1997. Invasive infections due to a fish pathogen, Streptococcus iniae. N. Engl. J. Med. 337: 589 594.
200. Weiss, E.,, and G. A. Dasch. 1982. Differential characteristics of strains of Rochalimaea: Rochalimaea vinsonni sp. nov., the Canadian vole agent. Int. J. Syst. Bacteriol. 32: 305 314.
201. Wells, J. G.,, B. R. Davis,, I. K. Wachsmuth,, L. W. Riley,, R. S. Remis,, R. Sokolow,, and G. K. Morris. 1983. Laboratory investigation of hemorrhagic colitis outbreaks associated with a rare Escherichia coli serotype. J. Clin. Microbiol. 18: 512 520.
202. Whitby, D.,, M. Howard,, M. Tenant-Flowers,, N. S. Brink,, A. Copas,, C. Boshoff,, T. Hatzioannov,, F. E. Suggett,, D. M. Aldam,, A. S. Denton,, R. F. Miler,, I. V. D. Weller,, R. A. Weiss,, R. S. Teder,, and T. F. Schulz. 1995. Detection of Kaposi’s sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi’s sarcoma. Lancet 346: 799 802.
203. Wilesmith, J. W.,, G. A. H. Wells,, M. P. Cranwell,, and J. B. Ryan. 1988. Bovine sponjpgorm encephalopathy: epidemiological studies. Vet. Rec. 123: 638 644.
204. Will, R. G.,, J. W. Ironside,, M. Zeidler,, S. N. Cousens,, K. Estibiero,, A. Alperovitch,, S. Poser,, M. Pocchiari,, A. Hofman,, and P. G. Smith. 1996. A new variant of Creutzfeldt-Jacob disease in the UK. Lancet 347: 921 925.
205. Wong, C. S.,, S. Jelacic,, R. L. Babeeb,, S. L. Watkins,, and P. I. Tarr. 2000. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N. Engl. J. Med. 342: 1930-– 1936.
206. Wong, M. T.,, D. C. Thorton,, R. C. Kennedy,, and M. J. Dolan. 1995. A chemically defined liquid medium that supports primary isolation of Rochalimaea ( Bartonella) henselae from blood and tissue specimens. J. Clin. Microbiol. 33: 742.
207. World Health Organization. 1976. Ebola hemorrhagic fever in Zaire, 1976. Report of an international commission. Bull. W. H. O. 56: 271293.
208. World Health Organization. 1978. Ebola hemorrhagic fever in Sudan, 1976. Report of a WHO/international study. Bull. W. H. O. 56: 274277.
209. Yamanishi, K.,, T. Okuno,, K. Shiraki,, M. Takahashi,, T. Kondo,, Y. Asano,, and T. Kurata. 1988. Identification of human herpesvirus-6 as a casual agent for exanthem subitum. Lancet i: 1065 1067.
210. Zhong, J.-C.,, C. Metroka,, M. Reitz,, J. Nicholas,, and G. S. Hayward. 1997. Strain variability among Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genomes: evidence that a large cohort of United States AIDS patients may have been infected by a single common isolate. J. Virol. 71: 2505 2511.


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Clinical and laboratory abnormalities in human monocytotropic and granulocytotropic ehrlichioses

Citation: Suh B, Kostman J, Maniglia R. 2002. Emerging Infectious Diseases, p 396-412. In Truant A (ed), Manual of Commercial Methods in Clinical Microbiology. ASM Press, Washington, DC. doi: 10.1128/9781555817961.ch16

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