Chapter 12 : Bartonellosis

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Carrión's disease, the first identified bartonellosis, is a hemolytic, vasculoproliferative disorder of people in the Andes Mountains of Peru, Colombia, and Ecuador. The disease, caused by , went largely ignored until late in the 20th century, when it was found as a complicating infection of immune-compromised people causing a condition termed bacillary angiomatosis (BA). Two new pathogenic species, and , were also isolated from BA patients. Erythrocyte invasion is a strategy utilized by spp. Blood or tissue culture is one of the most clinically useful tools to document active infection. bacteremia can persist in clinically healthy cats for months to sometimes years. The presence of bacteremia can be intermittent or recurrent in some cats, making multiple sampling necessary. Blood for culture should be taken in an aseptic manner and placed into sterile EDTA tubes or directly into centrifugation-lysis tubes. Blood samples can be frozen and thawed prior to culture to produce erythrocyte lysis, which improves the sensitivity of isolation and rapidity of colony formation. Vaccination of cats would seem desirable to decrease potential human exposure to . Cats that are treated and recover from bacteremia following experimental intradermal infections with cultured organisms appear to be resistant to homologous strains on rechallenge.

Citation: Greene C, Krause D. 2000. Bartonellosis, p 245-258. In Brown C, Bolin C (ed), Emerging Diseases of Animals. ASM Press, Washington, DC. doi: 10.1128/9781555818050.ch12
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Table 1

Clinically important members of the genus

Citation: Greene C, Krause D. 2000. Bartonellosis, p 245-258. In Brown C, Bolin C (ed), Emerging Diseases of Animals. ASM Press, Washington, DC. doi: 10.1128/9781555818050.ch12

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