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Pursuing Drug-Resistant Bacteria, Page 1 of 2
< Previous page Next page > /docserver/preview/fulltext/10.1128/9781555818128/9781555811907_Chap17-1.gif /docserver/preview/fulltext/10.1128/9781555818128/9781555811907_Chap17-2.gifAbstract:
The excitement of being on his own in research in Italy groomed the author for other research experiences. With Raymond, who became both mentor and friend, the author worked independently in the area of radiation genetics. During his hematology fellowship, he followed up some research that he had begun with Charlotte Friend, placing leukemic spleens subcutaneously back into leukemic mice and noting prolongation of their lives. Stemming from the author’s experience with Watanabe, he also investigated the ecology of drug resistance and resistance plasmids. Bacteria have responded to the widespread applications of antibiotics by finding ways to become resistant, insensitive to the killing effects of these powerful drugs. The overuse of antibacterial agents kills off susceptible bacteria, enabling competitor flora in the environment to proliferate and cause infection, as well as causing some bacteria to actually develop mutations conferring resistance. The author is a voice for the proper use of antibiotics, and carries the message around the globe that we must make peace with the bacteria.