Modification and Editing of RNA

Editors: Henri Grosjean1, Rob Benne2
Affiliations: 1: Laboratoire d'Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France; 2: Department of Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Content Type: Monograph
Format: Hardcover
Publication Year: 1998

Category: Microbial Genetics and Molecular Biology

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This volume examines the various aspects of post-transcriptional RNA processing, including biosynthetic, genetic, and functional aspects of nucleoside modification and editing by nucleoside conversion as well as by nucleoside insertion/deletion.

Written by leading researchers in the field, it includes descriptions of the different types of modification/editing, identification of the correspondending enzymes, discussion of cis- and trans- acting sequences, machineries, mechanisms, cellular locations, the biological role of individual modified/edited bases, involvement in diseases like cancer and AIDS, and possible evolutionaly connections between different processes.

is a valuable reference for researchers, teachers and students, and will be a useful tool for the planning of future research to solve many questions that remain.

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