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Chapter 48 : Immunological Tests in Tuberculosis

Author: Christine M. Litwin1
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Affiliations: 1: Department of Pathology and Laboratory Medicine, Medical University of South Carolina, 171 Ashley Ave., Charleston, SC 29425
Content Type: Reference
Publication Year: 2016

Category: Immunology

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Abstract:

Tuberculosis (TB) is one of the most common serious bacterial infections and remains a major challenge to global health. One-third of the human population has been infected with Globally, drug-resistant tuberculosis is emerging as a new epidemic, with approximately 0.5 million new multidrug-resistant cases annually. TB is second only to HIV as a worldwide cause of death from an infectious disease, and HIV infection, in turn, is a major risk factor for TB.

Citation: Litwin C. 2016. Immunological Tests in Tuberculosis, p 433-443. In Detrick B, Schmitz J, Hamilton R (ed), Manual of Molecular and Clinical Laboratory Immunology, Eighth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818722.ch48
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References

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Tables

Immunological Tests in Tuberculosis
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Citation: Litwin C. 2016. Immunological Tests in Tuberculosis, p 433-443. In Detrick B, Schmitz J, Hamilton R (ed), Manual of Molecular and Clinical Laboratory Immunology, Eighth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818722.ch48
/content/10.1128/9781555818722.ch48.ch48tab1
TABLE 1

Definition of a positive tuberculin test

Generic image for table
TABLE 1

Definition of a positive tuberculin test

Citation: Litwin C. 2016. Immunological Tests in Tuberculosis, p 433-443. In Detrick B, Schmitz J, Hamilton R (ed), Manual of Molecular and Clinical Laboratory Immunology, Eighth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818722.ch48
/content/10.1128/9781555818722.ch48.ch48tab2
TABLE 2

Methodological characteristics of T-SPOT and QFT-GIT assays

Generic image for table
TABLE 2

Methodological characteristics of T-SPOT and QFT-GIT assays

Citation: Litwin C. 2016. Immunological Tests in Tuberculosis, p 433-443. In Detrick B, Schmitz J, Hamilton R (ed), Manual of Molecular and Clinical Laboratory Immunology, Eighth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818722.ch48
/content/10.1128/9781555818722.ch48.ch48tab3
TABLE 3

Sensitivities and specificities of QFT-GIT, T-SPOT, and TST assays

Generic image for table
TABLE 3

Sensitivities and specificities of QFT-GIT, T-SPOT, and TST assays

Citation: Litwin C. 2016. Immunological Tests in Tuberculosis, p 433-443. In Detrick B, Schmitz J, Hamilton R (ed), Manual of Molecular and Clinical Laboratory Immunology, Eighth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818722.ch48

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