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Category: Immunology
Mycoplasma: Immunologic and Molecular Diagnostic Methods, Page 1 of 2
< Previous page | Next page > /docserver/preview/fulltext/10.1128/9781555818722/9781555818715_CH49-1.gif /docserver/preview/fulltext/10.1128/9781555818722/9781555818715_CH49-2.gifAbstract:
Mycoplasmas and ureaplasmas are members of a unique group of organisms (class Mollicutes) that are characterized by their small genomes, lack of cell walls, sterols in cell membranes, and complex nutritional requirements. The role of Mycoplasma and Ureaplasma species in human diseases was largely underappreciated until recent years. As a result, most diagnostic laboratories ignored them. Because of their complex nutritional requirements as well as their adaptation to the host during infection, these fastidious organisms can be difficult and time-consuming to culture from patient samples. However, there are improved methods for detection, including PCR detection assays, serologic assays, and commercially available growth media, but these are still limited compared with the products for other organisms.
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Major commercial serologic test formats for M. pneumoniae in the United States
Major commercial serologic test formats for M. pneumoniae in the United States
Examples of M. pneumoniae nucleic acid amplification assays
Examples of M. pneumoniae nucleic acid amplification assays
Examples of real-time PCR-based assays and gene targets for detection of urogenital mycoplasmas
Examples of real-time PCR-based assays and gene targets for detection of urogenital mycoplasmas