Chapter 52 : The and

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The three families of bacteria described in this chapter share several common characteristics despite the phylogenetic distance between the group that includes and , from the , and the more distantly related in the class. All three genera are zoonotic bacteria with species capable of infecting both animals and humans and are fastidious with special growth requirements; many species among these three genera cause emerging infections in humans. The diversity of natural animal reservoirs for members of the genera and are just now becoming fully defined and appreciated and are likely all around us. spp. and spp. are well-established as agents that warrant special attention and focus because of their potential for misuse and intentional release in acts of bioterrorism or biowarfare. This chapter briefly summarizes our knowledge of the taxonomy, epidemiology, and pathobiology of these zoonotic bacteria and describes the immunologic and molecular tools for the laboratory diagnosis of infections caused by these microbes.

Citation: Litwin C, Anderson B, Tsolis R, Rasley A. 2016. The and , p 473-482. In Detrick B, Schmitz J, Hamilton R (ed), Manual of Molecular and Clinical Laboratory Immunology, Eighth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818722.ch52
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Taxonomy of the major human pathogens in the families , , and . Additional spp. and spp. not shown here have also been associated with human disease but are not listed due to space constraints. Members of the and genera are , while members of the genus are .

Citation: Litwin C, Anderson B, Tsolis R, Rasley A. 2016. The and , p 473-482. In Detrick B, Schmitz J, Hamilton R (ed), Manual of Molecular and Clinical Laboratory Immunology, Eighth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818722.ch52
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