Chapter 80 : Introduction

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Introduction, Page 1 of 1

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The prevalence of allergic diseases has risen dramatically throughout the world in recent years, creating a major health care burden. While immunoglobulin E (IgE) has been recognized to play a central role in the pathogenesis of human allergic conditions since 1967, a multitude of inflammatory mediators and cells are now known to contribute to these common phenotypes. Section L covers laboratory investigations useful in the diagnosis and management of allergic disorders. Important topics covered include the allergen, and assays to screen for the presence of allergen-specific IgE and other mediators of allergic inflammation, and analytic approaches to diagnosing food allergy, hypereosinophilic syndromes, and mast cell disorders.

Citation: Guerrerio P. 2016. Introduction, p 781-783. In Detrick B, Schmitz J, Hamilton R (ed), Manual of Molecular and Clinical Laboratory Immunology, Eighth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818722.ch80
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