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Chapter 16.10 : Smallpox—Variola Major

Editor: Amy L. Leber1
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Affiliations: 1: Editor in chief, Department of Laboratory Medicine, Nationwide Children’s Hospital, Columbus, Ohio
Content Type: Reference
Publication Year: 2016

Category: Clinical Microbiology

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Abstract:

Smallpox is a serious, contagious, and sometimes fatal infectious disease. There is no specific treatment for smallpox disease, and the only prevention is vaccination. In the United States and its territories, a suspected case of smallpox must be immediately reported to the appropriate local, state, or territorial health department.

Citation: Leber A. 2016. Smallpox—Variola Major, p 16.10.1-16.10.5. In Clinical Microbiology Procedures Handbook, Fourth Edition. ASM Press, Washington, DC. doi: 10.1128/9781555818814.ch16.10
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References

/content/book/10.1128/9781555818814.chap16.10
1. Centers for Disease Control and Prevention. Smallpox. http://emergency.cdc.gov/agent/smallpox/index.asp
2. Gelderblom HR, Hazelton PR. 2000. Specimen collection for electron microscopy. Emerg Infect Dis 6: 433– 434. Available at: http://wwwnc.cdc.gov/eid/article/6/4/00-0427_article.htm
3. Hazelton PR, Gelderblom HR. 2003. Electron microscopy for rapid diagnosis of infectious agents in emergent situations. Emerg Infect Dis 9: 294– 303. Available at: http://wwwnc.cdc.gov/eid/article/9/3/02-0327_article.
4. Miller SE. 2003. Bioterrorism and electron microscopic differentiation of poxviruses from herpesviruses: Dos and Don’t’s. Ultrastruct Pathol 27: 133– 140.
5. Seward JF, Galil K, Damon E, Norton SA, Rotz L, Schmid S, Harpaz R, Cono J, Marin M, Hutchins S, Chaves SS, McCauley MM. 2004. Development and experience with an algorithm to evaluate suspected smallpox cases in the United States, 2002-2004. Clin Infect Dis 39: 1477– 1483.
6. U.S. Department of Health and Human Services. Centers for Disease Control and Prevention. National Institutes of Health. 2007. Biosafety in Microbiological and Biomedical Laboratories (BMBL), 5th ed. U.S. Government Printing Office, Washington, DC. Available at http://www.cdc.gov/OD/OHS/biosfty/bmbl5/bmbl_5th_edition.

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