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Chapter 12 : Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque

Author: Nicholas S. Jakubovics1
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Affiliations: 1: School of Dental Sciences, Newcastle University, UK
Content Type: Monograph
Publication Year: 2015

Category: Bacterial Pathogenesis

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Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque, Page 1 of 2

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Abstract:

Despite major improvements in oral hygiene over the last few decades, dental caries and periodontitis remain two of the most common diseases in industrialized countries. For example, in the most recent National Health and Nutrition Examination Survey conducted between 2009–2010 in the U.S., almost one in four children between 3–9 years living in poverty had untreated dental caries ( ). In the U.K., almost 50% of children have obvious decay experience in permanent teeth by the age of 15 years ( ). Periodontitis, an inflammatory condition that involves the loss of the supporting structures of teeth, is more common in older age groups. In the U.S., over one-third of adults ≥30 years have moderate to severe periodontitis ( ). Both dental caries and periodontitis are caused by the growth of microbial biofilms on tooth surfaces, known as dental plaque.

Citation: Jakubovics N. 2015. Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque, p 263-277. In Conway T, Cohen P (ed), Metabolism and Bacterial Pathogenesis. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MBP-0013-2014
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Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque
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Citation: Jakubovics N. 2015. Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque, p 263-277. In Conway T, Cohen P (ed), Metabolism and Bacterial Pathogenesis. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MBP-0013-2014
/content/10.1128/9781555818883.chap12.fig12-1
Figure 1
Metabolic interactions between oral bacteria A. Food web based on observed nutrient interactions between oral bacteria (see text for details). Black arrows indicate nutrients produced or consumed by a single organism; colored lines show nutrient feeding between groups of organisms. The production of maltose from has not yet been confirmed. The extracellular environment contains a pool of digestive enzymes produced by different microorganisms. Extracellular enzymes capable of degrading proteins, carbohydrates, or DNA are indicated, and different types of protease or glycosidase are indicated by different colors. B. Proximity of sp. cells (green, labelled with antibodies against sp. PK1910) and cells (red, labelled with antibodies against receptor polysaccharide) in 8 h dental plaque formed on the surface of an enamel chip in the mouth of a volunteer. Scale bar = 20 μm. Part B is from Palmer et al. ( ) with kind permission of the lead author.
10.1128/9781555818883/fig12-1_thmb.gif
10.1128/9781555818883/fig12-1.gif
Image of Figure 1
Figure 1

Metabolic interactions between oral bacteria A. Food web based on observed nutrient interactions between oral bacteria (see text for details). Black arrows indicate nutrients produced or consumed by a single organism; colored lines show nutrient feeding between groups of organisms. The production of maltose from has not yet been confirmed. The extracellular environment contains a pool of digestive enzymes produced by different microorganisms. Extracellular enzymes capable of degrading proteins, carbohydrates, or DNA are indicated, and different types of protease or glycosidase are indicated by different colors. B. Proximity of sp. cells (green, labelled with antibodies against sp. PK1910) and cells (red, labelled with antibodies against receptor polysaccharide) in 8 h dental plaque formed on the surface of an enamel chip in the mouth of a volunteer. Scale bar = 20 μm. Part B is from Palmer et al. ( ) with kind permission of the lead author.

Citation: Jakubovics N. 2015. Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque, p 263-277. In Conway T, Cohen P (ed), Metabolism and Bacterial Pathogenesis. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MBP-0013-2014
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Tables

Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque
[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/10.1128/9781555818883.chap12-1,webId=/content/author/10.1128/9781555818883.chap12-1,properties={foaf_givenname=Nicholas S., foaf_name=Nicholas S. Jakubovics, foaf_surname=Jakubovics, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/10.1128/9781555818883.chap12-aff1]]}]]
Citation: Jakubovics N. 2015. Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque, p 263-277. In Conway T, Cohen P (ed), Metabolism and Bacterial Pathogenesis. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MBP-0013-2014
/content/10.1128/9781555818883.chap12.tab12-1
TABLE 1
Concentrations of major components of saliva
Generic image for table
TABLE 1

Concentrations of major components of saliva

Citation: Jakubovics N. 2015. Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque, p 263-277. In Conway T, Cohen P (ed), Metabolism and Bacterial Pathogenesis. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MBP-0013-2014

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