Chapter 2 : Pathogenesis — Thoughts from the Front Line

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Conventionally, the history of microbiology begins with the studies of Leeuwenhoek in the 17th century [this section is reviewed elegantly in Bulloch (1938)]. Using crude but ingenious microscopes fashioned by hand, this erstwhile haberdasher first revealed the unseen microbial world. It would take more than two centuries before the contributions of these microorganisms to the ecology of the biosphere would be revealed. Pasteur inaugurated the study of functional microbiology with his work on fermentation in the late 1850s. In 1863, he described the phenomenon of anaerobic microbial life and first coined the terms aerobic and anaerobic. Pasteur is of course best known for his many seminal contributions to microbial pathogenesis later in his life.

Citation: Nataro J. 2015. Pathogenesis — Thoughts from the Front Line, p 17-26. In Conway T, Cohen P (ed), Metabolism and Bacterial Pathogenesis. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MBP-0012-2014
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