Chapter 26 : Skin and Soft Tissue Infections

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Skin and soft tissue infections (SSTIs) encompass a variety of conditions, account for a large percentage of infections requiring hospitalization, and are associated with substantial morbidity ( ). SSTIs are clinical entities of variable presentation, etiology, and severity that involve microbial invasion of the layers of the skin and underlying soft tissues, ranging from mild infections, such as impetigo or ecthyma, to serious, life-threatening infections, such as necrotizing fasciitis ( ).

Citation: Moffarah A, Al Mohajer M, Hurwitz B, Armstrong D. 2016. Skin and Soft Tissue Infections, p 691-708. In Hayden R, Wolk D, Carroll K, Tang Y (ed),

Diagnostic Microbiology of the Immunocompromised Host, Second Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.DMIH2-0014-2015
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Figure 1

The Q-score system applies positive values to the number of polymorphonuclear cells (PMNs) and negative values to the number of squamous epithelial cells (SECs) observed in a direct Gram-stained smear of a wound ( ). The score starts at a maximum value of 3, and subtracts values, but the score never goes lower than zero; no negative numbers are used in the final score—rather, all negative numbers are rounded up to zero. When these assessment values are added together, the resulting number represents the Q score, which is used to determine the extent of culture work up of potential pathogens ( ). LPF, low power field.

Citation: Moffarah A, Al Mohajer M, Hurwitz B, Armstrong D. 2016. Skin and Soft Tissue Infections, p 691-708. In Hayden R, Wolk D, Carroll K, Tang Y (ed),

Diagnostic Microbiology of the Immunocompromised Host, Second Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.DMIH2-0014-2015
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Image of Figure 2
Figure 2

Description, diagnosis of, and comments on selected fungal infections that present as yeast in tissues.

Citation: Moffarah A, Al Mohajer M, Hurwitz B, Armstrong D. 2016. Skin and Soft Tissue Infections, p 691-708. In Hayden R, Wolk D, Carroll K, Tang Y (ed),

Diagnostic Microbiology of the Immunocompromised Host, Second Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.DMIH2-0014-2015
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Generic image for table
Table 1

SSTI dermatological presentation and specific microorganisms in immunocompromised non-HIV patients

Citation: Moffarah A, Al Mohajer M, Hurwitz B, Armstrong D. 2016. Skin and Soft Tissue Infections, p 691-708. In Hayden R, Wolk D, Carroll K, Tang Y (ed),

Diagnostic Microbiology of the Immunocompromised Host, Second Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.DMIH2-0014-2015
Generic image for table
Table 2

SSTI dermatological presentation with specific microorganisms in HIV-infected patients

Citation: Moffarah A, Al Mohajer M, Hurwitz B, Armstrong D. 2016. Skin and Soft Tissue Infections, p 691-708. In Hayden R, Wolk D, Carroll K, Tang Y (ed),

Diagnostic Microbiology of the Immunocompromised Host, Second Edition

. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.DMIH2-0014-2015

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