Chapter 8 : Ancient Resistome

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It is generally now known that the emergence of antibiotic resistance in bacteria is an ancient biological event, meaning that the existence of resistance genes predates our present-day use of antibiotics. In other words, antibiotic resistance is not a modern phenomenon. These findings have been made possible by emerging fields, such as paleomicrobiology, and paleo-environmental studies of ancient biological samples, deep subsurface environments, and isolated pristine environments that are free of contemporary sources (contemporary antibiotic compounds or genes) ( ). Paleomicrobiology has been employed to gain insight into ancient infections, such as the Black Death and Justinian’s plague, and has shown evidence of the involvement of bacteria in these pandemics ( ).

Citation: Olaitan A, Rolain J. 2016. Ancient Resistome, p 75-80. In Drancourt M, Raoult D (ed), Paleomicrobiology of Humans. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.PoH-0008-2015
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Antibiotic resistance genes uncovered from ancient samples

Citation: Olaitan A, Rolain J. 2016. Ancient Resistome, p 75-80. In Drancourt M, Raoult D (ed), Paleomicrobiology of Humans. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.PoH-0008-2015

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