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Chapter 10 : Dendritic Cells in the Immune System—History, Lineages, Tissues, Tolerance, and Immunity

Author: Jonathan M. Austyn1
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Affiliations: 1: Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
Content Type: Monograph
Publication Year: 2017

Category: Microbial Genetics and Molecular Biology

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Dendritic Cells in the Immune System—History, Lineages, Tissues, Tolerance, and Immunity, Page 1 of 2

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Abstract:

Ralph Steinman was posthumously awarded a Nobel Prize in 2011 “for his discovery of the dendritic cell and its role in adaptive immunity.” He first coined the term “dendritic cell” in 1973 while working with Zanvil Cohn. His findings laid the foundations for a new field of immunology. This has enormous therapeutic potential for new vaccination strategies against cancer and infectious diseases. It also holds promise for new therapies for autoimmune disease, allergy, and transplantation reactions.

Citation: Austyn J. 2017. Dendritic Cells in the Immune System—History, Lineages, Tissues, Tolerance, and Immunity, p 155-207. In Gordon S (ed), Myeloid Cells in Health and Disease. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MCHD-0046-2016
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