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Chapter 26 : G Protein-Coupled Receptors in Macrophages

Authors: Hsi-Hsien Lin1, Martin Stacey3
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Affiliations: 1: Department of Microbiology and Immunology, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan; 2: Chang Gung Immunology Consortium and Department of Anatomic Pathology, Chang Gung Memorial Hospital-Linkou, 333 Tao-Yuan, Taiwan; 3: School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
Content Type: Monograph
Publication Year: 2017

Category: Microbial Genetics and Molecular Biology

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Abstract:

G protein-coupled receptors (GPCRs) have been reviewed in depth elsewhere ( ); however, the following section summarizes our present knowledge of GPCR classification and mechanisms involved in GPCR-mediated signaling.

Citation: Lin H, Stacey M. 2017. G Protein-Coupled Receptors in Macrophages, p 485-505. In Gordon S (ed), Myeloid Cells in Health and Disease. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MCHD-0028-2016
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G Protein-Coupled Receptors in Macrophages
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Citation: Lin H, Stacey M. 2017. G Protein-Coupled Receptors in Macrophages, p 485-505. In Gordon S (ed), Myeloid Cells in Health and Disease. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MCHD-0028-2016
/content/10.1128/9781555819194.chap26.fig26-1
Figure 1

GPCR signaling and the activation/deactivation of heterotrimeric G proteins. Green circle, ligand; GAP, GTPase-activating protein; PI3K, phosphatidylinositol 3-kinase; PKC, protein kinase C; PLC, phospholipase C.

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10.1128/9781555819194/fig26-1.gif
Image of Figure 1
Figure 1

GPCR signaling and the activation/deactivation of heterotrimeric G proteins. Green circle, ligand; GAP, GTPase-activating protein; PI3K, phosphatidylinositol 3-kinase; PKC, protein kinase C; PLC, phospholipase C.

Citation: Lin H, Stacey M. 2017. G Protein-Coupled Receptors in Macrophages, p 485-505. In Gordon S (ed), Myeloid Cells in Health and Disease. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MCHD-0028-2016
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Tables

G Protein-Coupled Receptors in Macrophages
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Citation: Lin H, Stacey M. 2017. G Protein-Coupled Receptors in Macrophages, p 485-505. In Gordon S (ed), Myeloid Cells in Health and Disease. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MCHD-0028-2016
/content/10.1128/9781555819194.chap26.tab26-1
Table 1

Physiological and pathological roles of macrophage GPCRs

Generic image for table
Table 1

Physiological and pathological roles of macrophage GPCRs

Citation: Lin H, Stacey M. 2017. G Protein-Coupled Receptors in Macrophages, p 485-505. In Gordon S (ed), Myeloid Cells in Health and Disease. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.MCHD-0028-2016

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