Mobile DNA III

Editors: Nancy L. Craig1, Michael Chandler2, Martin Gellert3, Alan M. Lambowitz4, Phoebe A. Rice5, Suzanne B. Sandmeyer6
Affiliations: 1: Howard Hughes Medical Institute, Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine, Baltimore, MD; 2: Laboratoire de Microbiologie et Génétique Moléculaire, C.N.R.S., F-31062 Toulouse Cedex, France; 3: National Institutes of Health, Molecular Genetics Section, NIDDK, Bethesda, MD; 4: Institute for Cellular Molecular Biology and Department of Molecular Biosciences, University of Texas at Austin, Austin, TX; 5: Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL; 6: Departments of Biological Chemistry and Microbiology and Molecular Genetics, University of California, Irvine, Irvine, CA
Content Type: Monograph
Format: Electronic
Publication Year: 2015

Category: Clinical Microbiology

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Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability.

Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that

  • covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible
  • presents a detailed account of the many different recombination systems that can rearrange genomes
  • examines the tremendous impact of mobile DNA in virtually all organisms

is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms.

provides the most lucid reviews of these complex topics available anywhere.

provides a one-stop-shop for anyone wanting to keep abreast of current understanding of the activity of these elements and the enzymes that they encode. It should will be an invaluable resource for some time to come.”

—David Finnegan, Institute of Cell Biology, University of Edinburgh, King's Buildings.

Nancy L. Craig, is an Investigator with the Howard Hughes Medical Institute and a Professor in the Department of Molecular Biology and Genetics at the Johns Hopkins University School of Medicine. Dr. Craig is a member of the National Academy of Sciences and a Fellow of the American Association for the Advancement of Science, American Academy of Microbiology, and the American Academy of Arts and Sciences.

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