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Category: Viruses and Viral Pathogenesis
Viral Disease of the Eye, Page 1 of 2
< Previous page | Next page > /docserver/preview/fulltext/10.1128/9781555819439/9781555819422.ch10-1.gif /docserver/preview/fulltext/10.1128/9781555819439/9781555819422.ch10-2.gifAbstract:
The eye is a fascinating organ not only because of its complex anatomy but also because it is a partly immunologically privileged site, which protects itself from potentially destructive systemic immune responses. This characteristic, however, may hinder defense against infectious agents, including numerous viruses, which may manifest with a variety of ocular diseases (Table 1). The first part of this chapter discusses ocular anatomy and physiology, as well as the principle clinical syndromes, which are usually classified according to the affected anatomic structures. The latter part discusses the major viral ocular pathogens and highlights selected risk groups, such as infants and patients infected with human immunodeficiency virus (HIV).
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Anatomy of the eye. Courtesy of the National Eye Institute, National Institutes of Health, USA.
Anatomy of the eye. Courtesy of the National Eye Institute, National Institutes of Health, USA.
HIV retinopathy with cotton wool spots. Courtesy Retinal Gallery and S Cohen (http://retinagallery.com/displayimage.php?pid=3301).
HIV retinopathy with cotton wool spots. Courtesy Retinal Gallery and S Cohen (http://retinagallery.com/displayimage.php?pid=3301).
Herpes simplex virus keratitis with dendritic ulcer, visible after fluorescein staining.
Herpes simplex virus keratitis with dendritic ulcer, visible after fluorescein staining.
Herpes simplex virus keratitis with geographical ulcer. Courtesy of Hee K. Yang, Young K. Han, Won R. Wee, Jin H. Lee, and Ji W. Kwon; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea (http://www.jmedicalcasereports.com/content/5/1/328/figure/F1).
Herpes simplex virus keratitis with geographical ulcer. Courtesy of Hee K. Yang, Young K. Han, Won R. Wee, Jin H. Lee, and Ji W. Kwon; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea (http://www.jmedicalcasereports.com/content/5/1/328/figure/F1).
Cytomegalovirus retinitis with retinal haemorrhages and exudates. Courtesy Retinal Gallery and Don Gass (http://retinagallery.com/displayimage.php?pid=3989).
Cytomegalovirus retinitis with retinal haemorrhages and exudates. Courtesy Retinal Gallery and Don Gass (http://retinagallery.com/displayimage.php?pid=3989).
Herpes zoster ophthalmicus. Courtesy of William Charles Caccamise and Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa. Note the dermatomal distribution of the lesion and scar of Hutchinson's sign at the tip of the nose which may precede the development of herpes zoster ophthalmicus.
Herpes zoster ophthalmicus. Courtesy of William Charles Caccamise and Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa. Note the dermatomal distribution of the lesion and scar of Hutchinson's sign at the tip of the nose which may precede the development of herpes zoster ophthalmicus.
Courtesy of William Charles Caccamise and Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa.
Courtesy of William Charles Caccamise and Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa.
Eyelid molluscum contagiosum with typical umbillicated lesion. Courtesy Jesse Vislise and Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa.
Eyelid molluscum contagiosum with typical umbillicated lesion. Courtesy Jesse Vislise and Ophthalmic Atlas Images by EyeRounds.org, The University of Iowa.
Common viruses affecting the eye
Common viruses affecting the eye
Viral causes of ocular clinical syndromes
Viral causes of ocular clinical syndromes
Ocular HIV manifestations
Ocular HIV manifestations
Ocular manifestations of herpesviruses
Ocular manifestations of herpesviruses
Laboratory diagnosis of common ocular viral infections
Laboratory diagnosis of common ocular viral infections
Adenoviral ocular syndromes
Adenoviral ocular syndromes
Common congenital viral infections with ocular manifestations
Common congenital viral infections with ocular manifestations