Therapeutic Opportunities in the Vaginal Microbiome

Gregor Reid

doi:10.1128/microbiolspec.BAD-0001-2016

Chapter 6 : Therapeutic Opportunities in the Vaginal Microbiome

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Affiliations: 1: Lawson Health Research Institute and Departments of Microbiology and Immunology and Surgery, University of Western Ontario, London, Ontario, Canada

Content Type: Monograph

Publication Year: 2018

Category: Clinical Microbiology; General Interest

Book DOI: 10.1128/9781555819705

Chapter DOI: 10.1128/microbiolspec.BAD-0001-2016

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Abstract:

In order to design and apply a therapeutic, there must be a vaginal disease or disorder in need of treatment or a condition influenced by the vaginal microbiota. There must also be a way for a new therapeutic agent to function through the microbiome. Those conditions include bacterial vaginosis (BV), aerobic vaginitis (AV), urinary tract infection, urethritis, cervicitis, vulvovaginal candidiasis, vulvodynia, endometriosis, and chorioamnitis. In addition, sexually transmitted infections are included, as arguably some may be prevented by vaginal microbes. Cancer is included, not only because of the association with viral infection, but also because microbial dysbiosis has been associated with cancers at other sites.

Citation: Reid G. 2018. Therapeutic Opportunities in the Vaginal Microbiome, p 149-160. In Britton R, Cani P (ed), Bugs as Drugs. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.BAD-0001-2016

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Therapeutic Opportunities in the Vaginal Microbiome

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Figure 1a

Different mechanisms by which beneficial microbes might influence vaginal health.

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Figure 1a

Different mechanisms by which beneficial microbes might influence vaginal health.

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Figure 1b

Different mechanisms by which beneficial microbes might influence vaginal health.

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Figure 1b

Different mechanisms by which beneficial microbes might influence vaginal health.

References

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