Chapter 28 : Present and Future Surveillance of Antimicrobial Resistance in Animals: Principles and Practices

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There is broad consensus internationally that surveillance of the levels of antimicrobial resistance (AMR) occurring in various systems underpins strategies to address the issue. The key reasons for surveillance of resistance are to determine (i) the size of the problem, (ii) whether resistance is increasing, (iii) whether previously unknown types of resistance are emerging, (iv) whether a particular type of resistance is spreading, and (v) whether a particular type of resistance is associated with a particular outbreak. The implications of acquiring and utilizing this information need to be considered in the design of a surveillance system.

Citation: Simjee S, McDermott P, Trott D, Chuanchuen R. 2018. Present and Future Surveillance of Antimicrobial Resistance in Animals: Principles and Practices, p 595-618. In Schwarz S, Cavaco L, Shen J (ed), Antimicrobial Resistance in Bacteria from Livestock and Companion Animals. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.ARBA-0028-2017
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Figure 1

MIC distribution for a hypothetical bacterial species targeted in antimicrobial resistance surveillance programs. Arrows indicate the epidemiological cutoff value (ECOFF) established according to EUCAST recommendations, separating the wild type (no resistance determinants) from the non-wild type (presumed resistance determinants that could be verified by whole-genome sequencing analysis), and the clinical breakpoint. Susceptible, resistant, and intermediate value columns are indicated ( ).

Citation: Simjee S, McDermott P, Trott D, Chuanchuen R. 2018. Present and Future Surveillance of Antimicrobial Resistance in Animals: Principles and Practices, p 595-618. In Schwarz S, Cavaco L, Shen J (ed), Antimicrobial Resistance in Bacteria from Livestock and Companion Animals. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.ARBA-0028-2017
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Table 1

Antimicrobial classes and agents registered for human and veterinary use that are often screened in antimicrobial resistance surveillance programs

Citation: Simjee S, McDermott P, Trott D, Chuanchuen R. 2018. Present and Future Surveillance of Antimicrobial Resistance in Animals: Principles and Practices, p 595-618. In Schwarz S, Cavaco L, Shen J (ed), Antimicrobial Resistance in Bacteria from Livestock and Companion Animals. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.ARBA-0028-2017
Generic image for table
Table 2

Microorganisms of interest in AMR monitoring programs focused on both zoonotic foodborne pathogens and commensals in healthy livestock and major animal pathogens

Citation: Simjee S, McDermott P, Trott D, Chuanchuen R. 2018. Present and Future Surveillance of Antimicrobial Resistance in Animals: Principles and Practices, p 595-618. In Schwarz S, Cavaco L, Shen J (ed), Antimicrobial Resistance in Bacteria from Livestock and Companion Animals. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.ARBA-0028-2017

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