Chapter 21 : Tuberculous Lymphadenitis and Parotitis

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Tuberculosis (TB) of the lymphatic glands has afflicted humans for thousands of years. Scrofula is usually a term used to describe the swelling of the lymph nodes in the neck caused by TB; the name scrofula was given because pigs were considered susceptible to the disease, and it comes from the Latin , meaning brood sow. Hippocrates (460–377 BC) mentioned scrofulous tumors in his writing, and Herodotus (484–425 BC) described the exclusion of those afflicted with leprous or scrofulous lesions from the general population. In the Middle Ages, it was believed in England and France that a touch from royalty could heal skin disease known as scrofula or the “king’s evil.” The practice began in the 11th century in France with Robert the Pious (970–1031), King of France, and in England with King Edward the Confessor (1003–1066). Subsequent English and French kings were thought to have inherited this royal touch, which was supposed to show that their right to rule was God given. In grand ceremonies, kings touched hundreds of people afflicted by scrofula ( ).

Citation: Cataño J, Robledo J. 2017. Tuberculous Lymphadenitis and Parotitis, p 343-354. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0008-2016
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Figure 1

Multiple cervical lymphadenopathy in a patient with TB lymphadenitis. Computed tomography showing diffuse lymphadenopathy in cervical chains.

Citation: Cataño J, Robledo J. 2017. Tuberculous Lymphadenitis and Parotitis, p 343-354. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0008-2016
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Figure 2

Cervical scrofula. Sternal scrofula. Reprinted from reference , with permission.

Citation: Cataño J, Robledo J. 2017. Tuberculous Lymphadenitis and Parotitis, p 343-354. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0008-2016
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Figure 3

Endoscopy with esophageal fistula from esophagus to mediastinum. Contrasted chest computed tomography with a fistula from esophagus to mediastinum. Reprinted from reference , with permission.

Citation: Cataño J, Robledo J. 2017. Tuberculous Lymphadenitis and Parotitis, p 343-354. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0008-2016
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