Chapter 37 : Biologic Agents and Tuberculosis

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In recent years, the market of biopharmaceuticals has been growing at a fast pace due to increased availability of targets for biologic agents, approval of biologic agents for new and expanded indications, and increased use of these medications. Biopharmaceuticals, also known as biologic products or agents, biologics, or biologicals, are drugs that are produced through biological processes rather than chemical synthesis. These include recombinant proteins, monoclonal and polyclonal antibodies, peptides, antisense oligonucleotides, therapeutic genes, and recombinant and DNA vaccines. Biopharmaceuticals usually require infusion or injection rather than oral application.

Citation: Dobler C. 2017. Biologic Agents and Tuberculosis, p 623-635. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0026-2016
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Table 1

Drug-specific RR of TB

Citation: Dobler C. 2017. Biologic Agents and Tuberculosis, p 623-635. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0026-2016
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Table 2

Recommendations for LTBI screening and treatment in different countries

Citation: Dobler C. 2017. Biologic Agents and Tuberculosis, p 623-635. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0026-2016

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