Chapter 43 :

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The first report of a mycobacterium isolated in fish, supposed to be , has been attributed to Bataillon et al. (1897), who isolated acid-fast bacilli named from a tuberculous lesion in a common carp () ( ). was then originally isolated and identified from marine fish at the Philadelphia Aquarium ( ). was initially thought to infect marine fishes only and was named accordingly, but it is now known to be a ubiquitous species. The above-mentioned original freshwater isolate of could be a variant. In the early literature, several other marine species were described, such as , , and . Comparative sugar fermentative reactions together with published morphological, cultural, and pathogenic data suggested that they were all synonymous with ( ) even if has not been recognized as a species since its type culture is no longer available.

Citation: Aubry A, Mougari F, Reibel F, Cambau E. 2017. , p 735-752. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0038-2016
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Figure 1

Typical photochromogenic colonies of grown on Lowenstein-Jensen solid medium.

Citation: Aubry A, Mougari F, Reibel F, Cambau E. 2017. , p 735-752. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0038-2016
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Figure 2

Sporotrichoid form of skin lesions typical of infection. (Courtesy of Hervé Darie, Noisy le Grand, France.)

Citation: Aubry A, Mougari F, Reibel F, Cambau E. 2017. , p 735-752. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0038-2016
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Figure 3

Active-disease histopathologic section of tissue from a patient with a infection. The lesion shows granulomatous infiltrate with epithelioid and giant cells. (Courtesy of Bernard Cribier, Strasbourg, France.)

Citation: Aubry A, Mougari F, Reibel F, Cambau E. 2017. , p 735-752. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0038-2016
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Figure 4

Microbiological diagnosis of human infection due to .

Citation: Aubry A, Mougari F, Reibel F, Cambau E. 2017. , p 735-752. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0038-2016
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1. Bataillon E,, Moeller A,, Terre L . 1902. Über die identitat des Bacillus des Karpfens (Bataillon, Dubard et terre) und des bacillus der Blindsschleuche (Moeller). Zentralblatt für tuberculose 3 : 467 468.[PubMed]
2. Aronson J . 1926. Spontaneous tuberculosis in salt water fish. J Infect Dis 39 : 315 320.[PubMed]
3. Baker J,, Hagan W . 1942. Tuberculosis of a Mexican platyfish (Platypoecilus maculatus). J Infect Dis 70 : 248 252.
4. Linell F,, Norden A . 1954. Mycobacterium balnei, a new acid-fast bacillus occurring in swimming pools and capable of producing skin lesions in humans. Acta Tuberc Scand Suppl 33 : 1 84.
5. Ang P,, Rattana-Apiromyakij N,, Goh CL . 2000. Retrospective study of Mycobacterium marinum skin infections. Int J Dermatol 39 : 343 347.
6. Ruley KM,, Ansede JH,, Pritchett CL,, Talaat AM,, Reimschuessel R,, Trucksis M . 2004. Identification of Mycobacterium marinum virulence genes using signature-tagged mutagenesis and the goldfish model of mycobacterial pathogenesis. FEMS Microbiol Lett 232 : 75 81.
7. Behr MA,, Falkinham JO III . 2009. Molecular epidemiology of nontuberculous mycobacteria. Future Microbiol 4 : 1009 1020.[PubMed]
8. Wayne LG,, Sramek HA . 1992. Agents of newly recognized or infrequently encountered mycobacterial diseases. Clin Microbiol Rev 5 : 1 25.[PubMed]
9. Tortoli E . 2014. Microbiological features and clinical relevance of new species of the genus Mycobacterium . Clin Microbiol Rev 27 : 727 752.[PubMed]
10. Helguera-Repetto C,, Cox RA,, Muñoz-Sànchez JL,, Gonzalez-y-Merchand JA . 2004. The pathogen Mycobacterium marinum, a faster growing close relative of Mycobacterium tuberculosis, has a single rRNA operon per genome. FEMS Microbiol Lett 235 : 281 288.[PubMed]
11. Stahl DA,, Urbance JW . 1990. The division between fast- and slow-growing species corresponds to natural relationships among the mycobacteria. J Bacteriol 172 : 116 124.
12. Wolinsky E . 1992. Mycobacterial diseases other than tuberculosis. Clin Infect Dis 15 : 1 10.[PubMed]
13. Kurokawa S,, Kabayama J,, Hwang SD,, Nho SW,, Hikima J,, Jung TS,, Sakai M,, Kondo H,, Hirono I,, Aoki T . 2013. Comparative genome analysis of fish and human isolates of Mycobacterium marinum . Mar Biotechnol (New York) 15 : 596 605.[PubMed]
14. Rogall T,, Wolters J,, Flohr T,, Böttger EC . 1990. Towards a phylogeny and definition of species at the molecular level within the genus Mycobacterium . Int J Syst Bacteriol 40 : 323 330.[PubMed]
15. Tønjum T,, Welty DB,, Jantzen E,, Small PL . 1998. Differentiation of Mycobacterium ulcerans, M. marinum, and M. haemophilum: mapping of their relationships to M. tuberculosis by fatty acid profile analysis, DNA-DNA hybridization, and 16S rRNA gene sequence analysis. J Clin Microbiol 36 : 918 925.[PubMed]
16. Stinear TP,, Seemann T,, Pidot S,, Frigui W,, Reysset G,, Garnier T,, Meurice G,, Simon D,, Bouchier C,, Ma L,, Tichit M,, Porter JL,, Ryan J,, Johnson PD,, Davies JK,, Jenkin GA,, Small PL,, Jones LM,, Tekaia F,, Laval F,, Daffé M,, Parkhill J,, Cole ST . 2007. Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer. Genome Res 17 : 192 200.[PubMed]
17. Stinear TP,, Seemann T,, Harrison PF,, Jenkin GA,, Davies JK,, Johnson PD,, Abdellah Z,, Arrowsmith C,, Chillingworth T,, Churcher C,, Clarke K,, Cronin A,, Davis P,, Goodhead I,, Holroyd N,, Jagels K,, Lord A,, Moule S,, Mungall K,, Norbertczak H,, Quail MA,, Rabbinowitsch E,, Walker D,, White B,, Whitehead S,, Small PL,, Brosch R,, Ramakrishnan L,, Fischbach MA,, Parkhill J,, Cole ST . 2008. Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis . Genome Res 18 : 729 741.[PubMed]
18. Kim BJ,, Lee SH,, Lyu MA,, Kim SJ,, Bai GH,, Chae GT,, Kim EC,, Cha CY,, Kook YH . 1999. Identification of mycobacterial species by comparative sequence analysis of the RNA polymerase gene ( rpoB). J Clin Microbiol 37 : 1714 1720.[PubMed]
19. Dauendorffer JN,, Guillemin I,, Aubry A,, Truffot-Pernot C,, Sougakoff W,, Jarlier V,, Cambau E . 2003. Identification of mycobacterial species by PCR sequencing of quinolone resistance-determining regions of DNA gyrase genes. J Clin Microbiol 41 : 1311 1315.[PubMed]
20. Stinear TP,, Jenkin GA,, Johnson PD,, Davies JK . 2000. Comparative genetic analysis of Mycobacterium ulcerans and Mycobacterium marinum reveals evidence of recent divergence. J Bacteriol 182 : 6322 6330.[PubMed]
21. Stinear TP,, Mve-Obiang A,, Small PL,, Frigui W,, Pryor MJ,, Brosch R,, Jenkin GA,, Johnson PD,, Davies JK,, Lee RE,, Adusumilli S,, Garnier T,, Haydock SF,, Leadlay PF,, Cole ST . 2004. Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans . Proc Natl Acad Sci U S A 101 : 1345 1349.[PubMed]
22. Chemlal K,, Huys G,, Fonteyne PA,, Vincent V,, Lopez AG,, Rigouts L,, Swings J,, Meyers WM,, Portaels F . 2001. Evaluation of PCR-restriction profile analysis and IS 2404 restriction fragment length polymorphism and amplified fragment length polymorphism fingerprinting for identification and typing of Mycobacterium ulcerans and M. marinum . J Clin Microbiol 39 : 3272 3278.[PubMed]
23. Yip MJ,, Porter JL,, Fyfe JA,, Lavender CJ,, Portaels F,, Rhodes M,, Kator H,, Colorni A,, Jenkin GA,, Stinear T . 2007. Evolution of Mycobacterium ulcerans and other mycolactone-producing mycobacteria from a common Mycobacterium marinum progenitor. J Bacteriol 189 : 2021 2029.[PubMed]
24. Doig KD,, Holt KE,, Fyfe JA,, Lavender CJ,, Eddyani M,, Portaels F,, Yeboah-Manu D,, Pluschke G,, Seemann T,, Stinear TP . 2012. On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer. BMC Genomics 13 : 258. [PubMed]
25. Stragier P,, Hermans K,, Stinear T,, Portaels F . 2008. First report of a mycolactone-producing Mycobacterium infection in fish agriculture in Belgium. FEMS Microbiol Lett 286 : 93 95.[PubMed]
26. Ucko M,, Colorni A,, Kvitt H,, Diamant A,, Zlotkin A,, Knibb WR . 2002. Strain variation in Mycobacterium marinum fish isolates. Appl Environ Microbiol 68 : 5281 5287.[PubMed]
27. Ranger BS,, Mahrous EA,, Mosi L,, Adusumilli S,, Lee RE,, Colorni A,, Rhodes M,, Small PL . 2006. Globally distributed mycobacterial fish pathogens produce a novel plasmid-encoded toxic macrolide, mycolactone F. Infect Immun 74 : 6037 6045.[PubMed]
28. Prouty MG,, Correa NE,, Barker LP,, Jagadeeswaran P,, Klose KE . 2003. Zebrafish- Mycobacterium marinum model for mycobacterial pathogenesis. FEMS Microbiol Lett 225 : 177 182.[PubMed]
29. Ramakrishnan L,, Falkow S . 1994. Mycobacterium marinum persists in cultured mammalian cells in a temperature-restricted fashion. Infect Immun 62 : 3222 3229.[PubMed]
30. Talaat AM,, Trucksis M . 2000. Transformation and transposition of the genome of Mycobacterium marinum . Am J Vet Res 61 : 125 128.[PubMed]
31. Chan K,, Knaak T,, Satkamp L,, Humbert O,, Falkow S,, Ramakrishnan L . 2002. Complex pattern of Mycobacterium marinum gene expression during long-term granulomatous infection. Proc Natl Acad Sci U S A 99 : 3920 3925.[PubMed]
32. van Ingen J,, de Zwaan R,, Dekhuijzen R,, Boeree M,, van Soolingen D . 2009. Region of difference 1 in nontuberculous Mycobacterium species adds a phylogenetic and taxonomical character. J Bacteriol 191 : 5865 5867.[PubMed]
33. Talaat AM,, Reimschuessel R,, Wasserman SS,, Trucksis M . 1998. Goldfish, Carassius auratus, a novel animal model for the study of Mycobacterium marinum pathogenesis. Infect Immun 66 : 2938 2942.[PubMed]
34. Trucksis M . 2000. Fishing for mycobacterial virulence genes: a promising animal model. ASM News 66 : 668 674.
35. Dionne MS,, Ghori N,, Schneider DS . 2003. Drosophila melanogaster is a genetically tractable model host for Mycobacterium marinum . Infect Immun 71 : 3540 3550.[PubMed]
36. Cosma CL,, Swaim LE,, Volkman H,, Ramakrishnan L,, Davis JM . 2006. Zebrafish and frog models of Mycobacterium marinum infection. Curr Protoc Microbiol Unit 10B.2. [PubMed]
37. Swaim LE,, Connolly LE,, Volkman HE,, Humbert O,, Born DE,, Ramakrishnan L . 2006. Mycobacterium marinum infection of adult zebrafish causes caseating granulomatous tuberculosis and is moderated by adaptive immunity. Infect Immun 74 : 6108 6117.[PubMed]
38. Weerdenburg EM,, Abdallah AM,, Mitra S,, de Punder K,, van der Wel NN,, Bird S,, Appelmelk BJ,, Bitter W,, van der Sar AM . 2012. ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish. Cell Microbiol 14 : 728 739.[PubMed]
39. Sridevi JP,, Anantaraju HS,, Kulkarni P,, Yogeeswari P,, Sriram D . 2014. Optimization and validation of Mycobacterium marinum-induced adult zebrafish model for evaluation of oral anti-tuberculosis drugs. Int J Mycobacteriol 3 : 259 267.[PubMed]
40. Cronan MR,, Tobin DM . 2014. Fit for consumption: zebrafish as a model for tuberculosis. Dis Model Mech 7 : 777 784.[PubMed]
41. Barker LP,, George KM,, Falkow S,, Small PL . 1997. Differential trafficking of live and dead Mycobacterium marinum organisms in macrophages. Infect Immun 65 : 1497 1504.[PubMed]
42. Gao LY,, Groger R,, Cox JS,, Beverley SM,, Lawson EH,, Brown EJ . 2003. Transposon mutagenesis of Mycobacterium marinum identifies a locus linking pigmentation and intracellular survival. Infect Immun 71 : 922 929.[PubMed]
43. Tobin DM,, Vary JC Jr,, Ray JP,, Walsh GS,, Dunstan SJ,, Bang ND,, Hagge DA,, Khadge S,, King MC,, Hawn TR,, Moens CB,, Ramakrishnan L . 2010. The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell 140 : 717 730.[PubMed]
44. Singh VK,, Berry L,, Bernut A,, Singh S,, Carrère-Kremer S,, Viljoen A,, Alibaud L,, Majlessi L,, Brosch R,, Chaturvedi V,, Geurtsen J,, Drancourt M,, Kremer L . 2016. A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence of Mycobacterium marinum in multiple hosts. Cell Microbiol 18 : 1489 1507.[PubMed]
45. Barker LP,, Brooks DM,, Small PL . 1998. The identification of Mycobacterium marinum genes differentially expressed in macrophage phagosomes using promoter fusions to green fluorescent protein. Mol Microbiol 29 : 1167 1177.[PubMed]
46. Stamm LM,, Morisaki JH,, Gao LY,, Jeng RL,, McDonald KL,, Roth R,, Takeshita S,, Heuser J,, Welch MD,, Brown EJ . 2003. Mycobacterium marinum escapes from phagosomes and is propelled by actin-based motility. J Exp Med 198 : 1361 1368.[PubMed]
47. Hagedorn M,, Rohde KH,, Russell DG,, Soldati T . 2009. Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hosts. Science 323 : 1729 1733.[PubMed]
48. Pagán AJ,, Yang CT,, Cameron J,, Swaim LE,, Ellett F,, Lieschke GJ,, Ramakrishnan L . 2015. Myeloid growth factors promote resistance to mycobacterial infection by curtailing granuloma necrosis through macrophage replenishment. Cell Host Microbe 18 : 15 26.[PubMed]
49. Mohanty S,, Jagannathan L,, Ganguli G,, Padhi A,, Roy D,, Alaridah N,, Saha P,, Nongthomba U,, Godaly G,, Gopal RK,, Banerjee S,, Sonawane A . 2015. A mycobacterial phosphoribosyltransferase promotes bacillary survival by inhibiting oxidative stress and autophagy pathways in macrophages and zebrafish. J Biol Chem 290 : 13321 13343.[PubMed]
50. Zhang Q,, Wang D,, Jiang G,, Liu W,, Deng Q,, Li X,, Qian W,, Ouellet H,, Sun J . 2016. EsxA membrane-permeabilizing activity plays a key role in mycobacterial cytosolic translocation and virulence: effects of single-residue mutations at glutamine 5. Sci Rep 6 : 32618. [PubMed]
51. van der Sar AM,, Abdallah AM,, Sparrius M,, Reinders E,, Vandenbroucke-Grauls CM,, Bitter W . 2004. Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence. Infect Immun 72 : 6306 6312.[PubMed]
52. Cernoch P,, Enns R,, Saubolle M, . 1994. Cumitechs 16A, Laboratory Diagnoses of the Mycobacterioses. Coordinating ed., Weissfeld AS . American Society for Microbiology, Washington, DC.
53. Glickman MS, . 2008. Cording, cord factors, and trehalose dimycolate, p 63 73. In Daffe M,, Reyrat J (ed), The Mycobacterial Cell Envelope. ASM Press, Washington, DC.
54. Julián E,, Roldán M,, Sánchez-Chardi A,, Astola O,, Agustí G,, Luquin M . 2010. Microscopic cords, a virulence-related characteristic of Mycobacterium tuberculosis, are also present in nonpathogenic mycobacteria. J Bacteriol 192 : 1751 1760.[PubMed]
55. Daffé M,, Lanéelle MA,, Lacave C . 1991. Structure and stereochemistry of mycolic acids of Mycobacterium marinum and Mycobacterium ulcerans . Res Microbiol 142 : 397 403.[PubMed]
56. Ramakrishnan L,, Tran HT,, Federspiel NA,, Falkow S . 1997. A crtB homolog essential for photochromogenicity in Mycobacterium marinum: isolation, characterization, and gene disruption via homologous recombination. J Bacteriol 179 : 5862 5868.[PubMed]
57. Russo C,, Tortoli E,, Menichella D . 2006. Evaluation of the new GenoType Mycobacterium assay for identification of mycobacterial species. J Clin Microbiol 44 : 334 339.[PubMed]
58. Tortoli E,, Nanetti A,, Piersimoni C,, Cichero P,, Farina C,, Mucignat G,, Scarparo C,, Bartolini L,, Valentini R,, Nista D,, Gesu G,, Tosi CP,, Crovatto M,, Brusarosco G . 2001. Performance assessment of new multiplex probe assay for identification of mycobacteria. J Clin Microbiol 39 : 1079 1084.[PubMed]
59. Salati F,, Meloni M,, Fenza A,, Angelucci G,, Colorni A,, Orrù G . 2010. A sensitive FRET probe assay for the selective detection of Mycobacterium marinum in fish. J Fish Dis 33 : 47 56.[PubMed]
60. Holmes GF,, Harrington SM,, Romagnoli MJ,, Merz WG . 1999. Recurrent, disseminated Mycobacterium marinum infection caused by the same genotypically defined strain in an immunocompromised patient. J Clin Microbiol 37 : 3059 3061.[PubMed]
61. Sechi LA,, Colorni A,, Duprè I,, Molicotti P,, Fadda G,, Zanetti S . 2002. Strain variation in Mediterranean and Red Sea Mycobacterium marinum isolates. New Microbiol 25 : 351 356.[PubMed]
62. Stragier P,, Ablordey A,, Meyers WM,, Portaels F . 2005. Genotyping Mycobacterium ulcerans and Mycobacterium marinum by using mycobacterial interspersed repetitive units. J Bacteriol 187 : 1639 1647.[PubMed]
63. Ucko M,, Colorni A . 2005. Mycobacterium marinum infections in fish and humans in Israel. J Clin Microbiol 43 : 892 895.[PubMed]
64. Harriff MJ,, Bermudez LE,, Kent ML . 2007. Experimental exposure of zebrafish, Danio rerio (Hamilton), to Mycobacterium marinum and Mycobacterium peregrinum reveals the gastrointestinal tract as the primary route of infection: a potential model for environmental mycobacterial infection. J Fish Dis 30 : 587 600.[PubMed]
65. Jacobs JM,, Rhodes MR,, Baya A,, Reimschuessel R,, Townsend H,, Harrell RM . 2009. Influence of nutritional state on the progression and severity of mycobacteriosis in striped bass Morone saxatilis. Dis Aquat Organ 87 : 183 197.[PubMed]
66. Ramsay JM,, Watral V,, Schreck CB,, Kent ML . 2009. Husbandry stress exacerbates mycobacterial infections in adult zebrafish, Danio rerio (Hamilton). J Fish Dis 32 : 931 941.[PubMed]
67. Decostere A,, Hermans K,, Haesebrouck F . 2004. Piscine mycobacteriosis: a literature review covering the agent and the disease it causes in fish and humans. Vet Microbiol 99 : 159 166.[PubMed]
68. Antuofermo E,, Pais A,, Polinas M,, Cubeddu T,, Righetti M,, Sanna MA,, Prearo M . 2 July 2016. Mycobacteriosis caused by Mycobacterium marinum in reared mullets: first evidence from Sardinia (Italy). J Fish Dis doi:10.1111/jfd.12515.
69. Caron J,, Michot C,, Fabre S,, Godreuil S,, Guillot B,, Dereure O . 2011. Aggressive cutaneous infection with Mycobacterium marinum in two patients receiving anti-tumor necrosis factor-alfa agents. J Am Acad Dermatol 65 : 1060 1062.[PubMed]
70. Danko JR,, Gilliland WR,, Miller RS,, Decker CF . 2009. Disseminated Mycobacterium marinum infection in a patient with rheumatoid arthritis receiving infliximab therapy. Scand J Infect Dis 41 : 252 255.[PubMed]
71. Dare JA,, Jahan S,, Hiatt K,, Torralba KD . 2009. Reintroduction of etanercept during treatment of cutaneous Mycobacterium marinum infection in a patient with ankylosing spondylitis. Arthritis Rheum 61 : 583 586.[PubMed]
72. Hess SD,, Van Voorhees AS,, Chang LM,, Junkins-Hopkins JM,, Kovarik CL . 2009. Subcutaneous Mycobacterium marinum infection in a patient with chronic rheumatoid arthritis receiving immunosuppressive therapy. Int J Dermatol 48 : 782 783.[PubMed]
73. Ramos JM,, García-Sepulcre MF,, Rodríguez JC,, Padilla S,, Gutiérrez F . 2010. Mycobacterium marinum infection complicated by anti-tumour necrosis factor therapy. J Med Microbiol 59 : 617 621.[PubMed]
74. Asakura T,, Ishii M,, Kikuchi T,, Kameyama K,, Namkoong H,, Nakata N,, Sugita K,, Tasaka S,, Shimizu T,, Hoshino Y,, Okamoto S,, Betsuyaku T,, Hasegawa N . 2016. Disseminated Mycobacterium marinum infection with a destructive nasal lesion mimicking extranodal NK/T cell lymphoma: a case report. Medicine (Baltimore) 95 : e3131. [PubMed]
75. Ribot E,, Poisnel E,, De Biasi C,, Roudier J,, Balandraud N . 2014. Atypical Mycobacterium marinum infection (aquarium granuloma) in a patient on TNFα antagonist therapy for psoriatic arthritis. Joint Bone Spine 81 : 272 273.[PubMed]
76. Kaneko S,, Seishima M,, Asano Y,, Chinuki Y,, Morita E . 2014. Mycobacterium marinum infection in a case of psoriasis treated with antitumor necrosis factor α antibody detected by QuantiFERON(®)-TB test. Int J Dermatol 53 : e187 e189.[PubMed]
77. Kump PK,, Högenauer C,, Wenzl HH,, Petritsch W . 2013. A case of opportunistic skin infection with Mycobacterium marinum during adalimumab treatment in a patient with Crohn’s disease. J Crohns Colitis 7 : e15 e18.[PubMed]
78. Demitsu T,, Yamada T,, Umemoto N,, Narita T,, Kakurai M,, Yoneda K . 2012. Cutaneous Mycobacterium marinum infection mimicking felon in a patient with psoriatic arthritis treated with infliximab. J Dermatol 39 : 970 971.[PubMed]
79. Alkhawaja S,, Tammam N,, Khalifa N . 2010. Mycobacterium marinum infection after infliximab therapy. Iran J Allergy Asthma Immunol 9 : 255 257.[PubMed]
80. Aubry A,, Chosidow O,, Caumes E,, Robert J,, Cambau E . 2002. Sixty-three cases of Mycobacterium marinum infection: clinical features, treatment, and antibiotic susceptibility of causative isolates. Arch Intern Med 162 : 1746 1752.[PubMed]
81. Gluckman SJ . 1995. Mycobacterium marinum . Clin Dermatol 13 : 273 276.[PubMed]
82. Clark RB,, Spector H,, Friedman DM,, Oldrati KJ,, Young CL,, Nelson SC . 1990. Osteomyelitis and synovitis produced by Mycobacterium marinum in a fisherman. J Clin Microbiol 28 : 2570 2572.[PubMed]
83. Edelstein H . 1994. Mycobacterium marinum skin infections. Report of 31 cases and review of the literature. Arch Intern Med 154 : 1359 1364.[PubMed]
84. Zenone T,, Boibieux A,, Tigaud S,, Fredenucci JF,, Vincent V,, Chidiac C,, Peyramond D . 1999. Non-tuberculous mycobacterial tenosynovitis: a review. Scand J Infect Dis 31 : 221 228.[PubMed]
85. Riera J,, Conesa X,, Pisa J,, Moreno J,, Siles E,, Novell J . 2016. Septic arthritis caused by Mycobacterium marinum . Arch Orthop Trauma Surg 136 : 131 134.[PubMed]
86. Macek P,, Bodnarova M,, Zavada J,, Jezek P,, Pavlik I,, Slany M,, Havelkova M,, Stork J,, Duskova J,, Hanus T,, Kocvara R . 2011. Mycobacterium marinum epididymoorchitis: case report and literature review. Urol Int 87 : 120 124.[PubMed]
87. Nguyen HH,, Fadul N,, Ashraf MS,, Siraj DS . 2015. Osteomyelitis infection of Mycobacterium marinum: a case report and literature review. Case Rep Infect Dis 2015 : 905920. [PubMed]
88. Johnson MG,, Stout JE . 2015. Twenty-eight cases of Mycobacterium marinum infection: retrospective case series and literature review. Infection 43 : 655 662.[PubMed]
89. Lacaille F,, Blanche S,, Bodemer C,, Durand C,, De Prost Y,, Gaillard JL . 1990. Persistent Mycobacterium marinum infection in a child with probable visceral involvement. Pediatr Infect Dis J 9 : 58 60.[PubMed]
90. Streit M,, Böhlen LM,, Hunziker T,, Zimmerli S,, Tscharner GG,, Nievergelt H,, Bodmer T,, Braathen LR . 2006. Disseminated Mycobacterium marinum infection with extensive cutaneous eruption and bacteremia in an immunocompromised patient. Eur J Dermatol 16 : 79 83.[PubMed]
91. Tchornobay AM,, Claudy AL,, Perrot JL,, Lévigne V,, Denis M . 1992. Fatal disseminated Mycobacterium marinum infection. Int J Dermatol 31 : 286 287.[PubMed]
92. Lai CC,, Lee LN,, Chang YL,, Lee YC,, Ding LW,, Hsueh PR . 2005. Pulmonary infection due to Mycobacterium marinum in an immunocompetent patient. Clin Infect Dis 40 : 206 208.[PubMed]
93. Philpott JA Jr,, Woodburne AR,, Philpott OS,, Schaefer WB,, Mollohan CS . 1963. Swimming pool granuloma: a study of 290 cases. Arch Dermatol 88 : 158 162.[PubMed]
94. Sia TY,, Taimur S,, Blau DM,, Lambe J,, Ackelsberg J,, Yacisin K,, Bhatnagar J,, Ritter J,, Shieh WJ,, Muehlenbachs A,, Shulman K,, Fong D,, Kung E,, Zaki SR . 2016. Clinical and pathological evaluation of Mycobacterium marinum group skin infections associated with fish markets in New York City. Clin Infect Dis 62 : 590 595.[PubMed]
95. Jernigan JA,, Farr BM . 2000. Incubation period and sources of exposure for cutaneous Mycobacterium marinum infection: case report and review of the literature. Clin Infect Dis 31 : 439 443.[PubMed]
96. Lewis FM,, Marsh BJ,, von Reyn CF . 2003. Fish tank exposure and cutaneous infections due to Mycobacterium marinum: tuberculin skin testing, treatment, and prevention. Clin Infect Dis 37 : 390 397.[PubMed]
97. Arend SM,, van Meijgaarden KE,, de Boer K,, de Palou EC,, van Soolingen D,, Ottenhoff TH,, van Dissel JT . 2002. Tuberculin skin testing and in vitro T cell responses to ESAT-6 and culture filtrate protein 10 after infection with Mycobacterium marinum or M. kansasii . J Infect Dis 186 : 1797 1807.[PubMed]
98. Kobashi Y,, Mouri K,, Yagi S,, Obase Y,, Miyashita N,, Okimoto N,, Matsushima T,, Kageoka T,, Oka M . 2009. Clinical evaluation of the QuantiFERON-TB Gold test in patients with non-tuberculous mycobacterial disease. Int J Tuberc Lung Dis 13 : 1422 1426.[PubMed]
99. Funakoshi T,, Kazumi Y,, Okada R,, Nishimoto K,, Saito M,, Amagai M,, Shimura H,, Ohyama M . 2009. Intractable ulcer caused by Mycobacterium shinshuense: successful identification of mycobacterium strain by 16S ribosomal RNA 3′-end sequencing. Clin Exp Dermatol 34 : e712 e715.[PubMed]
100. Wallace R,, Glassroth J,, Griffith DE,, Olivier KN,, Cook JL,, Gordin F . 1997. Diagnosis and treatment of disease caused by nontuberculous mycobacteria. Am J Respir Crit Care Med 156 : S1 S25.[PubMed]
101. Pfyffer GE,, Welscher HM,, Kissling P,, Cieslak C,, Casal MJ,, Gutierrez J,, Rüsch-Gerdes S . 1997. Comparison of the Mycobacteria Growth Indicator Tube (MGIT) with radiometric and solid culture for recovery of acid-fast bacilli. J Clin Microbiol 35 : 364 368.[PubMed]
102. Kurokawa S,, Kabayama J,, Fukuyasu T,, Hwang SD,, Park CI,, Park SB,, del Castillo CS,, Hikima J,, Jung TS,, Kondo H,, Hirono I,, Takeyama H,, Aoki T . 2013. Bacterial classification of fish-pathogenic Mycobacterium species by multigene phylogenetic analyses and MALDI Biotyper identification system. Mar Biotechnol (New York) 15 : 340 348.[PubMed]
103. Pourahmad F,, Thompson KD,, Taggart JB,, Adams A,, Richards RH . 2008. Evaluation of the INNO-LiPA mycobacteria v2 assay for identification of aquatic mycobacteria. J Fish Dis 31 : 931 940.[PubMed]
104. Gauthier DT,, Rhodes MW . 2009. Mycobacteriosis in fishes: a review. Vet J 180 : 33 47. [PubMed] [PubMed]
105. Cribier B,, Aubry A,, Caumes E,, Cambau E,, Jarlier V,, Chosidow O . 2011. Histopathological study of Mycobacterium marinum infection. Ann Dermatol Venereol 138 : 17 22. (In French.) [PubMed] [PubMed]
106. Even-Paz Z,, Haas H,, Sacks T,, Rosenmann E . 1976. Mycobacterium marinum skin infections mimicking cutaneous leishmaniasis. Br J Dermatol 94 : 435 442. [PubMed] [PubMed]
107. El-Khalawany MA . 2014. Atypical mycobacterial cutaneous infections in Egyptians: a clinicopathological study. J Dermatol 41 : 303 310. [PubMed] [PubMed]
108. Nikaido H . 2003. Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev 67 : 593 656. [PubMed] [PubMed]
109. Aubry A,, Jarlier V,, Escolano S,, Truffot-Pernot C,, Cambau E . 2000. Antibiotic susceptibility pattern of Mycobacterium marinum . Antimicrob Agents Chemother 44 : 3133 3136. [PubMed] [PubMed]
110. Utrup LJ,, Moore TD,, Actor P,, Poupard JA . 1995. Susceptibilities of nontuberculosis mycobacterial species to amoxicillin-clavulanic acid alone and in combination with antimycobacterial agents. Antimicrob Agents Chemother 39 : 1454 1457. [PubMed] [PubMed]
111. Bråbäck M,, Riesbeck K,, Forsgren A . 2002. Susceptibilities of Mycobacterium marinum to gatifloxacin, gemifloxacin, levofloxacin, linezolid, moxifloxacin, telithromycin, and quinupristin-dalfopristin (Synercid) compared to its susceptibilities to reference macrolides and quinolones. Antimicrob Agents Chemother 46 : 1114 1116. [PubMed] [PubMed]
112. Brown-Elliott BA,, Crist CJ,, Mann LB,, Wilson RW,, Wallace RJ Jr . 2003. In vitro activity of linezolid against slowly growing nontuberculous mycobacteria. Antimicrob Agents Chemother 47 : 1736 1738. [PubMed] [PubMed]
113. Rhomberg PR,, Jones RN . 2002. In vitro activity of 11 antimicrobial agents, including gatifloxacin and GAR936, tested against clinical isolates of Mycobacterium marinum . Diagn Microbiol Infect Dis 42 : 145 147.
114. Vera-Cabrera L,, Brown-Elliott BA,, Wallace RJ Jr,, Ocampo-Candiani J,, Welsh O,, Choi SH,, Molina-Torres CA . 2006. In vitro activities of the novel oxazolidinones DA-7867 and DA-7157 against rapidly and slowly growing mycobacteria. Antimicrob Agents Chemother 50 : 4027 4029. [PubMed] [PubMed]
115. Parrish N,, Luethke R,, Dionne K,, Carroll K,, Riedel S . 2011. Case of Mycobacterium marinum infection with unusual patterns of susceptibility to commonly used antibiotics. J Clin Microbiol 49 : 2056 2058. [PubMed] [PubMed]
116. Wallace RJ Jr,, Wiss K . 1981. Susceptibility of Mycobacterium marinum to tetracyclines and aminoglycosides. Antimicrob Agents Chemother 20 : 610 612. [PubMed] [PubMed]
117. Lebrun L,, Onody C,, Vincent V,, Nordmann P . 1996. Evaluation of the Etest for rapid susceptibility testing of Mycobacterium avium to clarithromycin. J Antimicrob Chemother 37 : 999 1003. [PubMed] [PubMed]
118. Flynn CM,, Kelley CM,, Barrett MS,, Jones RN . 1997. Application of the Etest to the antimicrobial susceptibility testing of Mycobacterium marinum clinical isolates. J Clin Microbiol 35 : 2083 2086. [PubMed] [PubMed]
119. Werngren J,, Olsson-Liljequist B,, Gezelius L,, Hoffner SE . 2001. Antimicrobial susceptibility of Mycobacterium marinum determined by E-test and agar dilution. Scand J Infect Dis 33 : 585 588. [PubMed] [PubMed]
120. Chazel M,, Marchandin H,, Keck N,, Terru D,, Carrière C,, Ponsoda M,, Jacomo V,, Panteix G,, Bouzinbi N,, Bañuls AL,, Choisy M,, Solassol J,, Aubry A,, Godreuil S . 2016. Evaluation of the SLOMYCO Sensititre(®) panel for testing the antimicrobial susceptibility of Mycobacterium marinum isolates. Ann Clin Microbiol Antimicrob 15 : 30. [PubMed] [PubMed]
121. Huminer D,, Pitlik SD,, Block C,, Kaufman L,, Amit S,, Rosenfeld JB . 1986. Aquarium-borne Mycobacterium marinum skin infection. Report of a case and review of the literature. Arch Dermatol 122 : 698 703. [PubMed] [PubMed]
122. Chow SP,, Ip FK,, Lau JH,, Collins RJ,, Luk KD,, So YC,, Pun WK . 1987. Mycobacterium marinum infection of the hand and wrist. Results of conservative treatment in twenty-four cases. J Bone Joint Surg Am 69 : 1161 1168. [PubMed] [PubMed]
123. Iijima S,, Saito J,, Otsuka F . 1997. Mycobacterium marinum skin infection successfully treated with levofloxacin. Arch Dermatol 133 : 947 949.
124. Kozin SH,, Bishop AT . 1994. Atypical Mycobacterium infections of the upper extremity. J Hand Surg Am 19 : 480 487.
125. Bhatty MA,, Turner DP,, Chamberlain ST . 2000. Mycobacterium marinum hand infection: case reports and review of literature. Br J Plast Surg 53 : 161 165.
126. Heckert RA,, Elankumaran S,, Milani A,, Baya A . 2001. Detection of a new Mycobacterium species in wild striped bass in the Chesapeake Bay. J Clin Microbiol 39 : 710 715.
127. Zanoni RG,, Florio D,, Fioravanti ML,, Rossi M,, Prearo M . 2008. Occurrence of Mycobacterium spp. in ornamental fish in Italy. J Fish Dis 31 : 433 441.
128. Slany M,, Makovcova J,, Jezek P,, Bodnarova M,, Pavlik I . 2014. Relative prevalence of Mycobacterium marinum in fish collected from aquaria and natural freshwaters in central Europe. J Fish Dis 37 : 527 533.
129. Broutin V,, Bañuls AL,, Aubry A,, Keck N,, Choisy M,, Bernardet JF,, Michel C,, Raymond JC,, Libert C,, Barnaud A,, Stragier P,, Portaels F,, Terru D,, Belon C,, Dereure O,, Gutierrez C,, Boschiroli ML,, Van De Perre P,, Cambau E,, Godreuil S . 2012. Genetic diversity and population structure of Mycobacterium marinum: new insights into host and environmental specificities. J Clin Microbiol 50 : 3627 3634.
130. Leoni E,, Legnani P,, Mucci MT,, Pirani R . 1999. Prevalence of mycobacteria in a swimming pool environment. J Appl Microbiol 87 : 683 688.
131. Bouricha M,, Castan B,, Duchene-Parisi E,, Drancourt M . 2014. Mycobacterium marinum infection following contact with reptiles: vivarium granuloma. Int J Infect Dis 21 : 17 18.
132. Huaman MA,, Ribes JA,, Lohr KM,, Evans ME . 2015. Mycobacterium marinum infection after exposure to coal mine water. Open Forum Infect Dis 3 : ofv205.
133. Feng Y,, Xu H,, Wang H,, Zhang C,, Zong W,, Wu Q . 2011. Outbreak of a cutaneous Mycobacterium marinum infection in Jiangsu Haian, China. Diagn Microbiol Infect Dis 71 : 267 272.
134. Swift S,, Cohen H . 1962. Granulomas of the skin due to Mycobacterium balnei after abrasions from a fish tank. N Engl J Med 267 : 1244 1246.
135. Dobos KM,, Quinn FD,, Ashford DA,, Horsburgh CR,, King CH . 1999. Emergence of a unique group of necrotizing mycobacterial diseases. Emerg Infect Dis 5 : 367 378.
136. King AJ,, Fairley JA,, Rasmussen JE . 1983. Disseminated cutaneous Mycobacterium marinum infection. Arch Dermatol 119 : 268 270.
137. Good RC . 1980. From the Center for Disease Control. Isolation of nontuberculous mycobacteria in the United States, 1979. J Infect Dis 142 : 779 783.
138. van der Werf MJ,, Ködmön C,, Katalinić-Janković V,, Kummik T,, Soini H,, Richter E,, Papaventsis D,, Tortoli E,, Perrin M,, van Soolingen D,, Zolnir-Dovč M,, Ostergaard Thomsen V . 2014. Inventory study of non-tuberculous mycobacteria in the European Union. BMC Infect Dis 14 : 62.
139. Casal M,, Casal MM , Spanish Group of Mycobacteriology . 2001. Multicenter study of incidence of Mycobacterium marinum in humans in Spain. Int J Tuberc Lung Dis 5 : 197 199.
140. Astrofsky KM,, Schrenzel MD,, Bullis RA,, Smolowitz RM,, Fox JG . 2000. Diagnosis and management of atypical Mycobacterium spp. infections in established laboratory zebrafish (Brachydanio rerio) facilities. Comp Med 50 : 666 672.
141. Passantino A,, Macrì D,, Coluccio P,, Foti F,, Marino F . 2008. Importation of mycobacteriosis with ornamental fish: medico-legal implications. Travel Med Infect Dis 6 : 240 244.
142. Dailloux M,, Laurain C,, Weber M,, Hartemann P . 1999. Water and nontuberculous mycobacteria. Water Res 33 : 2219 2228.
143. Parent LJ,, Salam MM,, Appelbaum PC,, Dossett JH . 1995. Disseminated Mycobacterium marinum infection and bacteremia in a child with severe combined immunodeficiency. Clin Infect Dis 21 : 1325 1327.[PubMed]
144. Schmoor P,, Descamps V,, Bouscarat F,, Grossin M,, Belaïch S,, Crickx B . 2003. Tropical fish salesmen’s knowledge and behaviour concerning “fish tank granuloma.” Ann Dermatol Venereol 130 : 425 427. (In French.)[PubMed]
145. Bonafe JL,, Grigorieff-Larrue N,, Bauriaud R . 1992. Atypical cutaneous mycobacterium diseases. Results of a national survey. Ann Dermatol Venereol 119 : 463 470.[PubMed]
146. Ho MH,, Ho CK,, Chong LY . 2006. Atypical mycobacterial cutaneous infections in Hong Kong: 10-year retrospective study. Hong Kong Med J 12 : 21 26.[PubMed]
147. Blanc P,, Dutronc H,, Peuchant O,, Dauchy FA,, Cazanave C,, Neau D,, Wirth G,, Pellegrin JL,, Morlat P,, Mercie P,, Tunon-de-Lara JM,, Doutre MS,, Pelissier P,, Dupon M . 2016. Nontuberculous mycobacterial infections in a French hospital: a 12-year retrospective study. PLoS One 11 : e0168290. [PubMed]


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Table 1

Published studies of infections that include more than 10 patients

Citation: Aubry A, Mougari F, Reibel F, Cambau E. 2017. , p 735-752. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0038-2016
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Table 2

MICs of 17 antibiotics against 54 strains of determined by the agar dilution method

Citation: Aubry A, Mougari F, Reibel F, Cambau E. 2017. , p 735-752. In Schlossberg D (ed), Tuberculosis and Nontuberculous Mycobacterial Infections, Seventh Edition. ASM Press, Washington, DC. doi: 10.1128/microbiolspec.TNMI7-0038-2016

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