Gram-Positive Pathogens, Third Edition

Editors: Vincent A. Fischetti1, Richard P. Novick2, Joseph J. Ferretti3, Daniel A. Portnoy4, Miriam Braunstein5, Julian I. Rood6
Affiliations: 1: The Rockefeller University; 2: Skirball Institute for Molecular Medicine, NYU Medical Center; 3: Department of Microbiology & Immunology, University of Oklahoma Health Science Center; 4: Department of Molecular and Cellular Microbiology, University of California, Berkeley; 5: Department of Microbiology and Immunology, University of North Carolina, Chapel Hill; 6: Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University
Content Type: Monograph
Format: Electronic
Publication Year: 2019

Category: Bacterial Pathogenesis

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Gram-positive bacteria, lacking an outer membrane and related secretory systems and having a thick peptidoglycan, have developed novel approaches to pathogenesis by acquiring (among others) a unique family of surface proteins, toxins, enzymes, and prophages. For the new edition, the editors have enhanced this fully researched compendium of Gram-positive bacterial pathogens by including new data generated using genomic sequencing as well as the latest knowledge on Gram-positive structure and mechanisms of antibiotic resistance and theories on the mechanisms of Gram-positive bacterial pathogenicity. This edition emphasizes streptococci, staphylococci, listeria, and spore-forming pathogens, with chapters written by many of the leading researchers in these areas. The chapters systematically dissect these organisms biologically, genetically, and immunologically, in an attempt to understand the strategies used by these bacteria to cause human disease.

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