Books

The understanding of clinical aspects, epidemiology, pathogenesis, genomic diversity, and glycobiology of Campylobacter infection has greatly increased. With the publication of this landmark third edition of Campylobacter, all the new findings, knowledge, and research are brought together in one comprehensive, up-to-date volume. As the number of species within the family has expanded, so has our knowledge of this group of organisms in terms of their physiology, population biology, and diversity. Additionally, new findings on the extent of campylobacter in the food supply, transmission of antibiotic resistant campylobacters from food animals to humans, and control of campylobacter at the food source are included.

Organized into six sections with thirty-eight chapters, this volume begins with chapters detailing the campylobacter organism. The next two sections thoroughly describe the clinical and epidemiologic aspects of campylobacter infections, pathogenesis, and immunity. The next section details the emerging field of campylobacter glycobiology, which has provided a structural basis for understanding important polysaccharides and glycolipids from the organism and offers great insight into glycosylation systems, which are present in other prokaryotes and eukaryotes. The volume then covers ground-breaking work on the molecular analyses of C. jejuni and other Campylobacter species. Finally, the volume addresses the growing body of work on improved food safety and intervention.

This volume will be a crucial resource for researchers and clinicians.

Hardcover, 716 pages, illustrations, index.

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Cases in Human Parasitology focuses solely on parasites that adversely affect humans. Intended as a supplement to textbooks in human parasitology for undergraduate and medical school courses, this book of 62 case studies is also an important educational reference source for health care scientists active in the field of parasitology.

The first four sections cover different groups of parasites, including intestinal protozoa; blood and tissue protozoa; cestodes, trematodes, and intestinal nematodes; and blood and tissue nematodes. The last section covers challenging cases and details non-parasitic infections in patients with symptoms closely resembling those of parasitic infections.

Each case study opens with a patient history and description of symptoms, and most are accompanied by a color image of the parasite described. Thought-provoking questions are posed, covering everything from diagnosis and the life cycle of the identified parasite to epidemiology and prevention. The questions stimulate discussion while emphasizing the relationship of diagnosis to patient care. Cases present new, emerging, and well-known parasites, and parasites infrequently encountered in the United States are included. The book concludes with a glossary of descriptive terms.

Cases in Human Parasitology is an excellent reinforcement of material learned in a clinical or laboratory setting. It will be useful for pathology residents and infectious disease fellows in preparing for board exams and it will serve in continuing the education of medical technologists involved in diagnostic parasitology.

Paperback, 243 pages, full-color illustrations, index.

The third edition of this best-selling text presents interesting and challenging cases that make the study of medical microbiology and infectious diseases enjoyable and enable students to develop a working knowledge of the variety of microorganisms that cause infections in humans.

Extensive introductory material explains in simple and concise language the strengths and weaknesses of different approaches that the clinical laboratory uses in assisting the physician in making infectious disease diagnoses. All of the approaches described are encountered in the cases that follow.

The 68 cases are presented as “unknowns” and represent actual case histories the authors have encountered at two university teaching hospitals. Each case is accompanied by several questions to test knowledge in four broad areas: 1) the etiologic agent's characteristics and laboratory diagnosis; 2) pathogenesis and clinical presentation; 3) epidemiology; and 4) prevention and, in some cases, drug resistance and treatment. Whenever possible, the authors have incorporated cellular microbiology into the case discussion.

Over 100 photographs allow students to familiarize themselves with the appearance of specific microorganisms in appropriate clinical settings. An extensive glossary explains the medical terminology to help students understand the language of medicine and make the cases accessible to all readers.

Cases in Medical Microbiology and Infectious Diseases is a valuable tool for students preparing for the National Board of Medical Examiners examination Parts 1 and 2 as well as during clinical infectious disease rotations. Advanced undergraduate students, other professional students, physicians in training at both the resident and fellow stage, and faculty members at all levels will all find Cases a useful resource.

Electronic Only, 440 pages, four-color illustrations throughout, glossary, index.

The term “cellular microbiology” was coined in 1996 to identify an emerging discipline integrating the fields of cell biology and microbiology. The advent of genomics, proteomics, and postgenomics has resulted in more widespread understanding of the field of cellular microbiology among scientists. Cellular Microbiology, 2nd Edition, considers genomic information and advances in technology in an updated examination of this burgeoning area of important research.

The second edition of this successful textbook offers five new chapters that comprehensively cover bacterial human pathogen genomes; structure and dynamics of the host cell membrane; study of prokaryotic biology using genome-wide approaches; cell biology of virus infection; and use of simple nonvertebrate hosts to model mammalian pathogenesis. All chapters are revised and organized like the first edition to provide fundamental details of each discipline along with the cellular microbiology aspects.

Solving real-world health challenges in a learning environment

You are at an exciting gateway into the world of microorganisms. With nothing more than basic lab equipment such as microscopes, Petri dishes, media, and a handful of reagents, you will learn to isolate, grow, and identify bacteria that live all around us. This is no ordinary microbiology laboratory course; not only will you learn how to streak plates, use a microscope, perform a Gram stain, and prepare serial dilutions and spread plates—fundamental skills found in every microbiologist’s toolkit—you will solve a series of public health–related challenges that many professional microbiologists encounter in their work.

By the end of this course, you will:

• Determine the origin of a nosocomial infection. Using foundational and molecular methods, you will determine whether the infections occurring in hospitalized patients are the result of contaminated medical items.
• Select the antibiotic to treat a patient with Crohn’s disease. You will find minimum inhibitory concentrations of various antibiotics for a Pseudomonas strain associated with Crohn’s disease.
• Pinpoint the source of lettuce contaminated with E. coli. Using molecular tools you will investigate a common food safety challenge, antibiotic-resistant E. coli and the potential for spread of this resistance in the environment.
• Find the farm releasing pathogens into a stream used for drinking water. Using bacteriophage load in water samples, you will locate the source of fecal contamination in the water supply of a village in an underdeveloped country.
• Evaluate the potential of bacteria to cause a urinary tract infection. You will test for biofilms, quorum sensing behavior, and chemotaxis and assess which disinfectants would be most effective for sanitizing contaminated surfaces.

Microbiology educators and researchers Richard Meyer and Stacie Brown have created this hands-on, engaging introduction to the essential laboratory skills in the microbial sciences that is sure to change the way you view the world around you.

Paperback, 200 pages, full-color illustrations, index.

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Within the last fifteen years, scientists have discovered that most groups of bacteria use a rich chemical lexicon to send and receive signals from other bacteria. Bacteria use these signals to coordinate a wide range of activities, including bioluminescence, sporulation, biofilm formation, horizontal DNA transfer, population density estimates, and pathogenesis. Understanding this communication will be crucial for future research in bacterial physiology, ecology, and bacterial disease. It may also be useful in intervening in bacterial processes, both harmful and beneficial.

This new volume of thirty chapters brings together the latest findings on chemical communication among bacteria and points towards potential areas for future research. Organized into four sections, this volume addresses: cell-cell signaling during development and DNA exchange; signaling in relationship to humans, animals, and plants; production and detection of chemical signals; and eukaryotic quorum sensing. Important new discoveries addressed include the structures of three bacterial signal synthases, signal receptors, mechanisms of signal transduction, pathways, and the expression of target genes.

Leading researchers in various aspects of bacterial signaling have contributed to this volume and provide a comprehensive overview of signal synthesis, detection, and its impacts on bacterial behavior. This indispensable book will be necessary reading for any microbiologist looking for a wide-ranging reference book on cell-cell signaling.

Hardcover, 483 pages, illustrations, index.

This informative and absorbing chronology presents events in the annals of microbiology in light of their historical context and identifies those individuals who made these events happen. Beginning in the 4th millennium B.C. with citations of ancient medicine and diseases, the chronology follows the development of microbiology and related sciences throughout the 18th and 19th centuries and culminates with the explosion of discoveries in the late 20th century.

Based on the premise that knowledge of contemporary events helps our understanding of how and why particular scientific advances were made, A Chronology of Microbiology includes advances in other scientific disciplines such as biochemistry, cell biology, genetics, microscopy, chemistry, and physics, as well as events from social, political, and cultural history.

Intended as a valuable resource for teachers and students, A Chronology of Microbiology in Historical Context provides a wealth of information not usually found in standard textbooks.

Electronic only, 391 pages, index.

Clinical Laboratory Management is a comprehensive volume presenting authoritative information on the management challenges facing today's clinical laboratories. Dramatic changes in the fields of medicine and healthcare require an increased level of expertise of all laboratory personnel. An invaluable resource for laboratory directors, managers, and supervisors, Clinical Laboratory Management will also teach healthcare practitioners at all levels how to hear, speak, and thoroughly understand the operational language of healthcare administration.

Written by practicing laboratorians and edited by seasoned professionals, this publication details the core requirements for effective laboratory management, including personnel management, communication, data management, point-of-care testing, test management, selection and implementation of tests and instruments, safety and emergency preparedness, and regulatory requirements. A comprehensive overview of management principles is presented, with in-depth analyses of financial challenges encountered in the clinical laboratory. Contained here is an array of administrative tools, including numerous appendices providing guidelines for relevant documentation, information on regulatory requirements, and managerial tools pertaining to personnel, financial, and technical issues, as well as checklists, worksheets, forms, Web addresses, and a complete glossary of specialized terms.

Clinical Laboratory Management is the essential resource for all clinical laboratories, from the physician's office to hospital clinical labs, to the largest commercial reference laboratories, providing practical information in the fields of medicine and healthcare, clinical pathology, and clinical laboratory management, for practitioners, managers, and individuals training to enter these fields.

Electronic only, 864 pages, illustrations, index.

The collaborative efforts of over 150 experienced clinical microbiologists, medical laboratory technologists, and laboratory supervisors are included in the third edition of the Clinical Microbiology Procedures Handbook. This well-respected reference continues to serve as the sole major publication providing step-by-step protocols and descriptions that enable clinical microbiologists and laboratory staff personnel to perform all analyses, including appropriate quality control recommendations, from the receipt of the specimen through processing, testing, interpretation, presentation of the final report, and subsequent consultation.

In response to the ever-changing needs and responsibilities of the clinical microbiology field, most sections of the third edition have been extensively reviewed and updated. To accommodate the expanding role of clinical microbiologists, the new edition places greater emphasis on areas such as molecular approaches, bioterrorism, safety, and epidemiology/infection control in medical facilities. Procedures are formatted to adhere to the GP02-5A (2006) document of the National Committee for Clinical Laboratory Standards/Clinical and Laboratory Standards Institute (NCCLS/CLSI). Procedures are divided into preanalytical, analytical, and postanalytical considerations, with extensive discussion of each category. The icons in the margin of the text relate to safety recommendations, the use of standard precautions, a reminder for the user to record relevant reagent dates (receipt, opened, and expiration), as well as to reinforce quality control.

Electronic only, 2,540 pages, illustrations, index.

Just Published!

The definitive clinical virology resource for physicians and clinical laboratory virologists

The clinical virology field is rapidly evolving and, as a result, physicians and clinical laboratory virologists must have a reliable reference tool to aid in their ability to identify and diagnose viral infections to prevent future outbreaks.

In this completely revised edition of the Clinical Virology Manual, Editor in Chief, Michael Loeffelholz, along with Section Editors, Richard Hodinka, Benjamin Pinsky, and Stephen Young, have complied expert perspectives of a renowned team of clinical virology experts and divided these contributions into three sections to provide

• the latest information on the diagnosis of viral infections, including ebola, HIV and Human papillomavirus
• state of the art diagnostic technologies, including next-generation sequencing and nucleic acid amplification methods
• taxonomy of clinically important viruses such as polyomaviruses and zoonotic viruses

This comprehensive reference also includes three appendices with vital information on reference virology laboratories at the Centers for Disease Control and Prevention, state and local public health laboratories, and international reference laboratories and laboratory systems.

Additionally, a new section “Diagnostic Best Practices,” which summarizes recommendations for diagnostic testing, and cites evidence-based guidelines, is included in each viral pathogens chapter.

Clinical Virology Manual, Fifth Edition serves as a reference source to healthcare professionals and laboratorians in providing clinical and technical information regarding viral diseases and the diagnosis of viral infections.

Hardcover, 622 pages, full-color illustrations, index.

The essential reference of clinical virology

Virology is one of the most dynamic and rapidly changing fields of clinical medicine. For example, sequencing techniques from human specimens have identified numerous new members of several virus families, including new polyomaviruses, orthomyxoviruses, and bunyaviruses.

Clinical Virology, Fourth Edition, has been extensively revised and updated to incorporate the latest developments and relevant research. Chapters written by internationally recognized experts cover novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, organized into two major sections:

• Section 1 provides information regarding broad topics in virology, including immune responses, vaccinology, laboratory diagnosis, principles of antiviral therapy, and detailed considerations of important organ system manifestations and syndromes caused by viral infections.
• Section 2 provides overviews of specific etiologic agents and discusses their biology, epidemiology, pathogenesis of disease causation, clinical manifestations, laboratory diagnosis, and management.

Clinical Virology provides the critical information scientists and health care professionals require about all aspects of this rapidly evolving field.

Hardcover, 1,489 pages, illustrations, index.

Practicing clinicians, trainees, infection control practitioners, and allied health professionals will find the pocket-sized Clinician's Dictionary portable and easy to use. Coverage of pathogenic bacteria, mycobacteria, fungi, viruses, and parasites that affect humans is comprehensive, yet quick and concise. The dictionary provides clinicians with a convenient means of understanding clinical features of the microorganisms they encounter.

Brand new in the field of clinical microbiology, the Clinician's Dictionary features a cross reference of new and old terminology of pathogenic microorganisms and includes material on not only the most common pathogens, but also on those less frequently recovered from patients. No other portable source of information examines species that may be resistant to therapy, defines various infectious syndromes, and affords users easy access to often esoteric organisms. For accurate interpretation of laboratory reports that may include new or unfamiliar organism names, this reference will be the first source of practical information.

Paperback, 273 pages.

Conceived by a team of authors with decades of classroom and laboraory experience, the Color Atlas of Medical Bacteriology includes more than 730 brilliant, four-color images of common pathogenic bacteria and descriptions of the methods used to identify them, including microscopic and phenotypic characteristics, colonial morphology, and biochemical properties.

Each chapter, organized by pathogen and taxonomic group, begins with a brief introduction that provides a contextual framework for the images. This second edition embraces the latest developments in molecular biology methodology in the diagnostic laboratory with a new chapter examining the breadth and possibilities of these new techniques. Also, in light of the alarming emergence of antibiotic resistance, antimicrobial susceptibiliy testing is addressed in another new chapter. The final chapter on stains, media, and reagents details the most common menthods and biochemical reactions used in the identification of pathogenic bacteria. The book's hundreds of illustrations, of typical stains, colony morphologies, and biochemical reactions of bacteria most frequently encountered in the clinical laboratory, have been thouroughly updated.

A valuable illustrative supplement for lectures and laboratory presentations, this easy-to-use atlas was written for laboratorians, clinicians, students, and anyone interested in the field of diagnostic medical bacteriology.

The Color Atlas of Medical Bacteriology is a good reference book that is fairly complete with wonderful images. It would be a welcome addition to the bookshelves of any teaching institution or clinical microbiology laboratory. 

– Clinical Infectious Diseases review of the first edition, written in 2006

Hardcover, 366 pages, color illustrations, index.

Since its first clinical appearance in an 1890s case report, Cryptococcus has dramatically advanced as a human fungal pathogen: it now infects approximately 1 million individuals per year, resulting in more than 600,000 annual mortalities, including one-third of all AIDS-associated deaths.

Featuring more than 100 expert authors from around the world, this book offers the full range of scientific and clinical perspectives needed to create this unique, comprehensive overview of Cryptococcus. It covers both the Cryptococcus neoformans and Cryptococcus gattii species, examining in detail the life cycle, pathophysiology, molecular biology, genetics, genomics, epidemiology, immunology, and clinical management of this encapsulated yeast. Among the 44 chapters, readers will find several in-depth discussions of the C. gattii outbreak that began on Vancouver Island in 1999 and then spread into the mainland of Canada and the United States, causing infections in both humans and animals.

This book’s detailed, thorough reviews of all the latest advances and progress in the field set a new standard for publications dedicated to a single fungal pathogen. While the book is dedicated to Cryptococcus, it does draw analogies to other pathogenic fungi and, more broadly, to other microbial pathogens. Moreover, this volume demonstrates why Cryptococcus has become a model system for the study and understanding of fungal pathogenesis. As a result, molecular biologists, microbiologists, public health officials, epidemiologists, and infectious disease clinicians will all find this clearly written, carefully referenced, and all-inclusive book to be a highly valuable resource.

Hardcover, 620 pages, full-color insert, illustrations, index.

Historic and culturally important objects, like all materials, are vulnerable to microbial attack. Over time, microorganisms can affect paint, wood, paper, glass, textiles, metal, wax, stone, polymers, and coatings. Microbial deterioration of heritage materials can be caused by the formation and growth of biofilms or by direct attack by a variety of microorganisms, all of which may be difficult to correct without also damaging the materials themselves. On the other hand, microbial processes can also be adapted to conserve and even restore heritage materials, pointing to the complex nature of microbial interactions with these irreplaceable materials.

Cultural Heritage Microbiology assembles over twenty scientific papers published during the past two decades, each presenting a major advance in some facet of this complex field. These seminal articles, by a wide range of international experts, are grouped by the historic material affected. Each section is introduced by a thorough review, written for this volume, which serves to introduce and synthesize these past studies and to combine them with the latest cutting-edge findings to present the most current state of the field. Extensive references in every chapter and article offer valuable resources for further investigation.

Cultural Heritage Microbiology is ideal for anyone concerned with recognizing and dealing with microbial deterioration of heritage materials. Professionals and students in microbiology, conservation science, archaeology, fine arts, architecture, museum conservation, and other fields will find here the most current knowledge and approaches to preserving cultural heritage objects for generations to come.

Key Features

• Provides a unique, single overview of the seminal literature in conservation microbiology
• Presents the current state of the art along with a synthesis of the major developments over the years
• Represents the findings of leading international experts and pioneers in the field
• Offers conservation scientists and conservators an inclusive view of the heritage conservation field plus extensive resources for further investigation

Hardcover, 348 pages, illustrations, color insert, index.