Books
Search, browse, and discover hundreds of books that ASM publishes by internationally renowned authors and editors with expertise in a broad range of microbiology disciplines. Here you can purchase print or ebooks: print books are shipped (added shipping charges) and ebooks are downloadable files, in your choice of either ePub or PDF. You can also buy downloadable books by the chapter. Note that you have 48 hours to download your purchase from this site, after which access ends. Ebook/echapter purchases are final and nonrefundable.
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9 results
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Sampling for Biological Agents in the Environment
- Content Type: Monograph
- Editors: Peter Emanuel, Jason W. Roos, Kakoli Niyogi
- Publication Year: 2008
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Abstract:
Resulting from a national conference of first responders, scientists, and industry representatives, Sampling for Biological Agents in the Environment presents best practices that will help standardize procedures and technology to properly sample for biological threat agents. The sampling issues, techniques, and equipment are explained for professionals involved in sampling and testing of hazardous materials. This volume is the first of its kind and presents novel ideas to address the diverse needs within the biological sampling field.
Hardcover, 294 pages, illustrations, index.
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The Second Messenger Cyclic Di-GMP
- Content Type: Monograph
- Editors: Alan J. Wolfe, Karen L. Visick
- Publication Year: 2010
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In recent years, researchers have discovered a new type of signaling mechanism based on cyclic di-GMP (c-di-GMP). This newly recognized second messenger is strongly associated with the transition between the motile and sessile states of many bacteria as well as the formation and dispersion of biofilms in many bacteria. The near universality of this second messenger in bacteria combined with the biomedical relevance and commercial importance of biofilms has generated much interest in c-di-GMP signaling research.
This book examines c-di-GMP signaling from a variety of angles, beginning with an introductory chapter that compares c-di-GMP to the better-known second messenger cAMP. Next, the book recounts the discovery of c-di-GMP, explains the important role of bioinformatics in the development and continued evolution of the field, and then describes the fundamental structure, function, regulation, and integration of c-di-GMP pathways. Further chapters explore the role of c-di-GMP in such diverse processes as flagellar biogenesis and motility, extracellular polysaccharide biosynthesis, biofilm development, virulence, and innate host immunity. The book ends with an expert forecast of the future of c-di-GMP signaling research and its applications.
Each chapter has been written and reviewed by leading pioneers in this rapidly evolving field. As the first book dedicated to c-di-GMP, it serves as a comprehensive reference on the state of the science for both experienced researchers and for those who are interested in discovering its many promising applications.
Hardcover, 356 pages, illustrations, index.
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Sequelae and Long-Term Consequences of Infectious Diseases
- Content Type: Monograph
- Editors: Pina M. Fratamico, James L. Smith, Kim A. Brogden
- Publication Year: 2009
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Abstract:
Discover the links between infection with pathogenic microorganisms and such chronic illnesses as cancer, paralysis, arthritis, peptic ulcer, cirrhosis, and neurological disorders. Written and edited by leading experts, Sequelae and Long-Term Consequences of Infectious Diseases reviews the mechanisms used by pathogens to infect mucous surfaces, enter and multiply in the host environment, interfere with host defenses, damage host tissues, and produce long-term consequences. The book also explores the genetic and immunological status of afflicted individuals in terms of infection, disease progression, symptoms, and treatment options.
The first chapter examines the difficulties in establishing critical links between an infectious etiology and a chronic illness. The next group of chapters explores diseases in which the evidence points to a specific bacterium, parasite, virus, fungus, or prion as the cause. There is also a chapter dedicated to diseases suspected of having an underlying infectious etiology, but for which no specific pathogen has been identified. Another chapter discusses epidemiological methods for confirming, refuting, or modifying the links between specific microorganisms and the complications and long-term consequences they cause. The final chapter examines the economic burden associated with the sequelae of infectious agents and suggests future directions for research.
Sequelae and Long-Term Consequences of Infectious Diseases fills a critical void in the scientific literature, offering evidence of the causal links between infectious agents and chronic disorders and, most importantly, stimulating new research in this area. The book offers new insights for anyone involved in the diagnosis, treatment, prevention, and study of infectious disease. It is a recommended graduate-level text, providing students with a deep understanding of the mechanisms of host-pathogen interactions.
Electronic Only, 509 pages, full-color insert, illustrations, index.
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Sex in Fungi : Molecular Determination and Evolutionary Implications
- Content Type: Monograph
- Publication Year: 2007
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Abstract:
Sexual reproduction is ubiquitous in nature. As the engine that drives genetic diversity, sex accelerates adaptation and removes deleterious mutations. As such, it plays a central role in the origin and success of species. Studies on the major groups within the fungal kingdom have provided significant and wide-ranging contributions on the molecular bases by which sexual identity and reproduction are defined and controlled. Sex in Fungi: Molecular Determination and Evolutionary Implications not only encompasses the current state of knowledge, but also serves as an invaluable resource that will guide new research on these systems and organisms.
Since John Raper’s pioneering studies with the basidiomycetes in the 1960s, and the elegant work of Ira Herskowitz with Saccharomyces, genetic, molecular, and genomic analyses of fungal sexual reproduction have helped to illuminate how sexual cycles function in, as well as drive, evolution. The biological principles involved are profound and can serve as general paradigms for how cell identity is established and maintained, how cells sense and respond to extracellular cues, the role of genetic rearrangements in generating changes in cell identity and fate, and how genomic regions governing sexual identity are organized and evolved.
Drawing on the great advances made over the past 10 years, this volume provides illuminating insights into the molecular details of cell-type specification, mating-type switching, pheromone perception and signaling, and cellular and nuclear fusion. The tremendous impact of comparative genomics on the analysis of mating is evident in many of the chapters in this book. This volume includes chapters on both model and pathogenic fungi as well as a section that looks forward to what we hope to learn in other fungal lineages. The book concludes with a selection of chapters on the implications of sex, and studies of experimental evolution, in a broader evolutionary context.
Hardcover, 542 pages, full-color insert, illustrations, index.
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Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy
- Content Type: Monograph
- Publication Year: 1999
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Abstract:
This volume offers a comprehensive review of the existing knowledge about sexually transmitted diseases (STDs) and adverse pregnancy outcomes. It identifies gaps in our knowledge, points out potential areas and tools for research, and discusses the implications for public health programs. Covering both those reproductive tract infections whose impact on pregnancy is clear and that are relatively well studied, as well as those reported more recently and whose adverse impacts, such as low birth weight and prematurity, are less clear, Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy is valuable reading for clinical microbiologists, pediatricians, perinatologists, gynecologists, obstetricians, and infectious disease researchers.
Electronic only, 372 pages, illustrations, index.
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The Spectrum of Neuro-AIDS Disorders : Pathophysiology, Diagnosis, and Treatment
- Content Type: Monograph
- Editors: Karl Goodkin, Paul Shapshak, Ashok Verma
- Publication Year: 2009
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Abstract:
In the decade-plus since the introduction of highly active antiretroviral therapy (HAART), clinicians and researchers have come to recognize the implications of the brain as a reservoir for resistant HIV, and the significance of this chronic infection to the patient’s functioning and prognosis. This unique volume covers the full scope of research on the neurological and neurobehavioral implications of HIV/AIDS, or “neuro-AIDS,” including the fields of microbiology and immunology.
In this book, noted researchers from all over the world examine the wide range of HIV-associated neurological and neurobehavioral disorders. Neuro-AIDS can affect the entire neuraxis, resulting in physiological, neurological, and neurobehavioral deficits ranging from distal sensory polyneuropathy and primary CNS lymphoma to HIV-associated neurocognitive impairment and disorders including HIV-associated dementia. Toxicities of the antiretroviral medications themselves are a serious concern
This book presents the wide variety of HIV-associated disorders and comorbidities with a look at the pre-HAART literature as well as the latest findings from the post-HAART era. Pathophysiology and selected neuroimaging techniques for diagnosis and assessment are examined in detail. In addition, this volume stands out for its chapters on specific patient populations such as women, children, minorities, and older persons, as well as special chapters addressing medico-legal and end-of-life concerns. The book concludes with a look at global issues and the future of neuro-AIDS in the HAART era.
Electronic Only, 537 pages, full-color insert, illustrations, index.
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Stable Isotope Probing and Related Technologies
- Content Type: Monograph
- Editors: J. Colin Murrell, Andrew S. Whiteley
- Publication Year: 2011
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Abstract:
The concept of using stable isotopes to label and track microbes and metabolites of interest is a very recent development in microbial ecology. This comprehensive, carefully edited book, featuring contributions from world leaders in the development and application of these technologies, is the first to present stable isotope probing (SIP) and its related technologies in a single volume.
Divided into three parts, the book begins with methodology, guiding researchers through the basic, tested, and proven protocols including DNA, RNA, protein, and phospholipid fatty acid (PLFA) SIP, from concept and history through detailed methodology, troubleshooting, and interpretation, to optimal and future uses. Next, the book explores the important and emerging applications of SIP in environmental microbiology, ranging from bioremediation and gene mining to carbon tracking and gut microflora function. The book concludes with explorations of further elegant isotope labeling technologies such as Raman-FISH, NanoSIMS, and isotope arrays.
Stable Isotope Probing and Related Technologies is recommended not only for students and researchers in environmental microbiology, but also for those who can apply these cutting-edge technologies to such fields as genomics, biotechnology, and medical microbiology. The book also provides readers with access to the current literature, making it the ideal starting point for investigating, developing, and implementing stable isotope technologies.
Hardcover, 345 pages, full-color insert, illustrations, index.
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Structural Biology of Bacterial Pathogenesis
- Content Type: Monograph
- Editors: Gabriel Waksman, Michael Caparon, Scott Hultgren
- Publication Year: 2005
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Abstract:
Recent technological advances have led to an outpouring of knowledge in the field of structural biology, yielding an abundance of informational resources available to researchers in the study of bacterial pathogenesis. Structural Biology of Bacterial Pathogenesis explores recent developments in the understanding of the molecular basis of bacterial infectious diseases, from structures involved in adhesion and host recognition to those describing elements of bacterial secretion systems. The first compilation of its kind, this new volume offers a convenient review of current research that will engage instructors, students, and professionals in the fields of bacterial pathogenesis and infectious diseases.
Replete with unique illustrations and written by experts, Structural Biology of Bacterial Pathogenesis provides a foundation for understanding the molecular interactions required for infection to occur. Readers will gain insight into the role structures play both in our comprehension of pathological processes and in the design of novel antibiotic compounds. Chapters address diverse topics, including host receptors of bacterial origin, sortase pathways in gram-positive bacteria, and bacterial secretion machinery. Illustrations emphasize general concepts related to each disease profiled, as well as concepts concerning the infectious agent causing it.
Electronic Only, 273 pages, full-color insert, illustrations, index.
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Superantigens : Molecular Basis for Their Role in Human Diseases
- Content Type: Monograph
- Editors: Malak Kotb, John D. Fraser
- Publication Year: 2007
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Abstract:
Superantigens is the first comprehensive examination of these fascinating proteins ever published. Organized into five sections and sixteen chapters, this volume provides an essential overview of many aspects of superantigen biology. A team of internationally respected researchers covers the basic molecular mechanisms of superantigen action, their structure and function, and their role in human diseases. Additionally, Superantigens explains the clinical consequences of superantigen intoxication and the latest therapeutic interventions to combat superantigen toxicity.
This volume emphasizes how newly discovered structural variations among superantigens affect their interactions with human immune cells. Most importantly, these structural and functional differences help explain the exacerbation of certain diseases and why certain superantigens are more effective in some tissues and not in others. Furthermore, the book emphasizes how this information can inform new research on the design and development of new intervention strategies to ameliorate superantigen responses in severe acute infections or chronic illnesses. Special attention is paid to the latest findings on staphylococcal, streptococcal, and mycoplasma toxins and their relationship to specific diseases. Finally, the potential for the use of superantigens in bioterrorism is discussed.
As the single most comprehensive volume on the subject, Superantigens is essential reading for researchers in the fields of microbiology, immunology, biotechnology, molecular medicine, and clinical infectious disease.
Electronic Only, 263 pages, full-color insert, illustrations, index.