Books

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This widely adopted textbook provides the essential content and skill-building tools for teaching the responsible conduct of scientific research. Scientific Integrity covers the breadth of concerns faced by scientists: protection of animal and human experimental subjects, scientific publication, intellectual property, conflict of interest, collaboration, record keeping, mentoring, and the social and ethical responsibilities of scientists. Learning activities and resources designed to elucidate the principles of scientific integrity include

• Dozens of highly relevant, interactive case studies for discussion in class or online
• Supported by a companion website that allows ready access to relevant online content
• Numerous print and online resources covering the newest research guidelines, regulations, mandates and policies
• Discussion questions, role-playing exercises, and survey tools to promote critical thought
• Documents including published rules of conduct, sample experimentation protocols, and patent applications

The new edition of Scientific Integrity responds to significant recent changes―new mandates, policies, laws, and other developments―in the field of responsible conduct of research. Dr. Macrina plants the seeds of awareness of existing, changing, and emerging standards in scientific conduct and provides the tools to promote critical thinking in the use of that information.
Scientific Integrity is the original turnkey text to guide the next generations of scientists as well as practicing researchers in the essential skills and approaches for the responsible conduct of science.

“Scientific Integrity should be on the bookshelf of the entire research community. With the ever-growing ability of science to positively impact society, education in the responsible conduct of research is increasingly important for all members of the community, from students through faculty, staff, and administrators.”

―Timothy Donohue, Professor of Bacteriology, University of Wisconsin-Madison, and Director, Great Lakes Bioenergy Research Center

For more on the book and information on requesting an examination copy please visit http://www.asmscience.org/instructors

Paperback, 450 pages, illustrations, index.

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Looking for additional ethics resources to support your Scientific Integrity purchase? Click here to download free scientific ethics articles from ASM’s Journal of Microbiology & Biology Education (JMBE)!

Discover the links between infection with pathogenic microorganisms and such chronic illnesses as cancer, paralysis, arthritis, peptic ulcer, cirrhosis, and neurological disorders. Written and edited by leading experts, Sequelae and Long-Term Consequences of Infectious Diseases reviews the mechanisms used by pathogens to infect mucous surfaces, enter and multiply in the host environment, interfere with host defenses, damage host tissues, and produce long-term consequences. The book also explores the genetic and immunological status of afflicted individuals in terms of infection, disease progression, symptoms, and treatment options.

The first chapter examines the difficulties in establishing critical links between an infectious etiology and a chronic illness. The next group of chapters explores diseases in which the evidence points to a specific bacterium, parasite, virus, fungus, or prion as the cause. There is also a chapter dedicated to diseases suspected of having an underlying infectious etiology, but for which no specific pathogen has been identified. Another chapter discusses epidemiological methods for confirming, refuting, or modifying the links between specific microorganisms and the complications and long-term consequences they cause. The final chapter examines the economic burden associated with the sequelae of infectious agents and suggests future directions for research.

Sequelae and Long-Term Consequences of Infectious Diseases fills a critical void in the scientific literature, offering evidence of the causal links between infectious agents and chronic disorders and, most importantly, stimulating new research in this area. The book offers new insights for anyone involved in the diagnosis, treatment, prevention, and study of infectious disease. It is a recommended graduate-level text, providing students with a deep understanding of the mechanisms of host-pathogen interactions.

Electronic Only, 509 pages, full-color insert, illustrations, index.

This volume offers a comprehensive review of the existing knowledge about sexually transmitted diseases (STDs) and adverse pregnancy outcomes. It identifies gaps in our knowledge, points out potential areas and tools for research, and discusses the implications for public health programs. Covering both those reproductive tract infections whose impact on pregnancy is clear and that are relatively well studied, as well as those reported more recently and whose adverse impacts, such as low birth weight and prematurity, are less clear, Sexually Transmitted Diseases and Adverse Outcomes of Pregnancy is valuable reading for clinical microbiologists, pediatricians, perinatologists, gynecologists, obstetricians, and infectious disease researchers.

Electronic only, 372 pages, illustrations, index.

The concept of using stable isotopes to label and track microbes and metabolites of interest is a very recent development in microbial ecology. This comprehensive, carefully edited book, featuring contributions from world leaders in the development and application of these technologies, is the first to present stable isotope probing (SIP) and its related technologies in a single volume.

Divided into three parts, the book begins with methodology, guiding researchers through the basic, tested, and proven protocols including DNA, RNA, protein, and phospholipid fatty acid (PLFA) SIP, from concept and history through detailed methodology, troubleshooting, and interpretation, to optimal and future uses. Next, the book explores the important and emerging applications of SIP in environmental microbiology, ranging from bioremediation and gene mining to carbon tracking and gut microflora function. The book concludes with explorations of further elegant isotope labeling technologies such as Raman-FISH, NanoSIMS, and isotope arrays.

Stable Isotope Probing and Related Technologies is recommended not only for students and researchers in environmental microbiology, but also for those who can apply these cutting-edge technologies to such fields as genomics, biotechnology, and medical microbiology. The book also provides readers with access to the current literature, making it the ideal starting point for investigating, developing, and implementing stable isotope technologies.

Hardcover, 345 pages, full-color insert, illustrations, index.

Superantigens is the first comprehensive examination of these fascinating proteins ever published. Organized into five sections and sixteen chapters, this volume provides an essential overview of many aspects of superantigen biology. A team of internationally respected researchers covers the basic molecular mechanisms of superantigen action, their structure and function, and their role in human diseases. Additionally, Superantigens explains the clinical consequences of superantigen intoxication and the latest therapeutic interventions to combat superantigen toxicity.

This volume emphasizes how newly discovered structural variations among superantigens affect their interactions with human immune cells. Most importantly, these structural and functional differences help explain the exacerbation of certain diseases and why certain superantigens are more effective in some tissues and not in others. Furthermore, the book emphasizes how this information can inform new research on the design and development of new intervention strategies to ameliorate superantigen responses in severe acute infections or chronic illnesses. Special attention is paid to the latest findings on staphylococcal, streptococcal, and mycoplasma toxins and their relationship to specific diseases. Finally, the potential for the use of superantigens in bioterrorism is discussed.

As the single most comprehensive volume on the subject, Superantigens is essential reading for researchers in the fields of microbiology, immunology, biotechnology, molecular medicine, and clinical infectious disease.

Electronic Only, 263 pages, full-color insert, illustrations, index.