Books
Search, browse, and discover hundreds of books that ASM publishes by internationally renowned authors and editors with expertise in a broad range of microbiology disciplines. Here you can purchase print or ebooks: print books are shipped (added shipping charges) and ebooks are downloadable files, in your choice of either ePub or PDF. You can also buy downloadable books by the chapter. Note that you have 48 hours to download your purchase from this site, after which access ends. Ebook/echapter purchases are final and nonrefundable.
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Chemical Communication among Bacteria
- Content Type: Monograph
- Editors: Stephen C. Winans, Bonnie L. Bassler
- Publication Year: 2008
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Abstract:
Within the last fifteen years, scientists have discovered that most groups of bacteria use a rich chemical lexicon to send and receive signals from other bacteria. Bacteria use these signals to coordinate a wide range of activities, including bioluminescence, sporulation, biofilm formation, horizontal DNA transfer, population density estimates, and pathogenesis. Understanding this communication will be crucial for future research in bacterial physiology, ecology, and bacterial disease. It may also be useful in intervening in bacterial processes, both harmful and beneficial.
This new volume of thirty chapters brings together the latest findings on chemical communication among bacteria and points towards potential areas for future research. Organized into four sections, this volume addresses: cell-cell signaling during development and DNA exchange; signaling in relationship to humans, animals, and plants; production and detection of chemical signals; and eukaryotic quorum sensing. Important new discoveries addressed include the structures of three bacterial signal synthases, signal receptors, mechanisms of signal transduction, pathways, and the expression of target genes.
Leading researchers in various aspects of bacterial signaling have contributed to this volume and provide a comprehensive overview of signal synthesis, detection, and its impacts on bacterial behavior. This indispensable book will be necessary reading for any microbiologist looking for a wide-ranging reference book on cell-cell signaling.
Hardcover, 483 pages, illustrations, index.
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Chlamydia : Intracellular Biology, Pathogenesis, and Immunity
- Content Type: Monograph
- Editor: Richard S. Stephens
- Publication Year: 1999
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Abstract:
This important and timely volume is the first complete review of chlamydial research in ten years. In that time there have been substantial research advances, and the entry of many researchers into the field heralds a new era. The expansion of the field, fueled by the identification of a new emerging chlamydial pathogen, Chlamydia pneumoniae, and the completion of genome sequences for C. trachomatis and C. pneumoniae, provides the impetus for a complete review of chlamydial research.
This new volume identifies the major issues and questions that will lead to future chlamydial research. It illustrates how genomics is changing the chlamydial research agenda and explores the role of cell biology and the immune response in pathogenesis and immunity.
Designed as a synthetic, comparative volume, this book comprehensively compares, contrasts, and integrates issues across all chlamydial species. The contributors provide a thorough review of previous research and indicate the top research needs in each area.
Electronic Only, 346 pages, illustrations, index.
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A Chronology of Microbiology in Historical Context
- Content Type: Trade
- Author: Raymond W. Beck
- Publication Year: 2000
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This informative and absorbing chronology presents events in the annals of microbiology in light of their historical context and identifies those individuals who made these events happen. Beginning in the 4th millennium B.C. with citations of ancient medicine and diseases, the chronology follows the development of microbiology and related sciences throughout the 18th and 19th centuries and culminates with the explosion of discoveries in the late 20th century.
Based on the premise that knowledge of contemporary events helps our understanding of how and why particular scientific advances were made, A Chronology of Microbiology includes advances in other scientific disciplines such as biochemistry, cell biology, genetics, microscopy, chemistry, and physics, as well as events from social, political, and cultural history.
Intended as a valuable resource for teachers and students, A Chronology of Microbiology in Historical Context provides a wealth of information not usually found in standard textbooks.
Electronic only, 391 pages, index.
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Clinical Bacteriology
- Content Type: Reference
- Authors: J. Keith Struthers, Roger P. Westran
- Publication Year: 2003
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Abstract:
This beautifully illustrated book introduces readers to the basic science of medical microbiology and relates it to clinical practice. Integrating concise text, over 270 full-color diagrams, and selected photomicrographs, the authors provide an understanding of bacterial infection and give the reader the necessary grounding to select the right antibiotics and follow logical diagnostic and management strategies.
Following introductory chapters on the nature, structure, and function of bacteria, the principles are then applied to each body system in turn, dealing with organisms, pathogenesis, diagnosis, treatment and public health. There are also chapters on infection in modern society for immuno-suppressed patients, and on infection control emphasizing the importance of good hygiene in preventing hospital-acquired infection.
The book is valuable for medical students, trainee physicians and microbiologists, laboratory biomedical scientists, and nurses working in infection control.
Key Features
- Provides basic understanding of antibiotics and bacterial infection
- Integrated concise text and over 270 full-color diagrams and photomicrographs to relate science to clinical practice
Paperback, 192 pages, 4-color throughout, index.
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Clinical Laboratory Management
- Content Type: Reference
- Editors: Lynne S. Garcia, Vickie S. Baselski, M. Desmond Burke, Dale A. Schwab, David L. Sewell, John C. H. Steele, Alice S. Weissfeld, David S. Wilkinson, Washington C. Winn
- Publication Year: 2004
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Abstract:
Clinical Laboratory Management is a comprehensive volume presenting authoritative information on the management challenges facing today's clinical laboratories. Dramatic changes in the fields of medicine and healthcare require an increased level of expertise of all laboratory personnel. An invaluable resource for laboratory directors, managers, and supervisors, Clinical Laboratory Management will also teach healthcare practitioners at all levels how to hear, speak, and thoroughly understand the operational language of healthcare administration.
Written by practicing laboratorians and edited by seasoned professionals, this publication details the core requirements for effective laboratory management, including personnel management, communication, data management, point-of-care testing, test management, selection and implementation of tests and instruments, safety and emergency preparedness, and regulatory requirements. A comprehensive overview of management principles is presented, with in-depth analyses of financial challenges encountered in the clinical laboratory. Contained here is an array of administrative tools, including numerous appendices providing guidelines for relevant documentation, information on regulatory requirements, and managerial tools pertaining to personnel, financial, and technical issues, as well as checklists, worksheets, forms, Web addresses, and a complete glossary of specialized terms.
Clinical Laboratory Management is the essential resource for all clinical laboratories, from the physician's office to hospital clinical labs, to the largest commercial reference laboratories, providing practical information in the fields of medicine and healthcare, clinical pathology, and clinical laboratory management, for practitioners, managers, and individuals training to enter these fields.
Electronic only, 864 pages, illustrations, index.
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Clinical Laboratory Management, Second Edition
- Content Type: Reference
- Editor: Lynne S. Garcia
- Publication Year: 2014
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Abstract:
Volume Editor: Lynne Shore Garcia, LSG & Associates
This totally revised second edition is a comprehensive volume presenting authoritative information on the management challenges facing today’s clinical laboratories.
- Provides thorough coverage of management topics such as managerial leadership, personnel, business planning, information management, regulatory management, reimbursement, generation of revenue, and more.
- Includes valuable administrative resources, including checklists, worksheets, forms, and online resources.
- Serves as an essential resource for all clinical laboratories, from the physician’s office to hospital clinical labs to the largest commercial reference laboratories, providing practical information in the fields of medicine and healthcare, clinical pathology, and clinical laboratory management, for practitioners, managers, and individuals training to enter these fields.
"Virtually all details of management and management skills are discussed and, while many management books lack a compelling reason for reading, this one should be a standard in every laboratory manager’s office library. ... Get it for yourself, give it as a gift—but make it a staple for the manager. "
— J. Michael Miller, Ph.D., D(ABMM), F(AAM); Director, Microbiology Technical Services, LLCHardcover, 1096 pages, illustrations, index.
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Clinical Microbiology Procedures Handbook, 3rd Edition
- Content Type: Reference
- Editor: Lynne S. Garcia
- Publication Year: 2010
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Abstract:
The collaborative efforts of over 150 experienced clinical microbiologists, medical laboratory technologists, and laboratory supervisors are included in the third edition of the Clinical Microbiology Procedures Handbook. This well-respected reference continues to serve as the sole major publication providing step-by-step protocols and descriptions that enable clinical microbiologists and laboratory staff personnel to perform all analyses, including appropriate quality control recommendations, from the receipt of the specimen through processing, testing, interpretation, presentation of the final report, and subsequent consultation.
In response to the ever-changing needs and responsibilities of the clinical microbiology field, most sections of the third edition have been extensively reviewed and updated. To accommodate the expanding role of clinical microbiologists, the new edition places greater emphasis on areas such as molecular approaches, bioterrorism, safety, and epidemiology/infection control in medical facilities. Procedures are formatted to adhere to the GP02-5A (2006) document of the National Committee for Clinical Laboratory Standards/Clinical and Laboratory Standards Institute (NCCLS/CLSI). Procedures are divided into preanalytical, analytical, and postanalytical considerations, with extensive discussion of each category. The icons in the margin of the text relate to safety recommendations, the use of standard precautions, a reminder for the user to record relevant reagent dates (receipt, opened, and expiration), as well as to reinforce quality control.
Electronic only, 2,540 pages, illustrations, index.
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Clinical Microbiology Procedures Handbook, Fourth Edition
- Content Type: Reference
- Editor: Amy L. Leber
- Publication Year: 2016
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In response to the ever-changing needs and responsibilities of the clinical microbiology field, Clinical Microbiology Procedures Handbook, Fourth Edition has been extensively reviewed and updated to present the most prominent procedures in use today.
The Clinical Microbiology Procedures Handbook provides step-by-step protocols and descriptions that allow clinical microbiologists and laboratory staff personnel to confidently and accurately perform all analyses, including appropriate quality control recommendations, from the receipt of the specimen through processing, testing, interpretation, presentation of the final report, and subsequent consultation.
Do you need access for multiple users? To purchase a site license contact Rachel Peckover .
Note, for bundle purchases VAT will be assessed at 50% of the total bundle price ($210 for non-members and $168 for members).
Three-Volume Set, 2,954 pages, full-color illustrations, index.
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Clinical Virology Manual, Fifth Edition
- Content Type: Reference
- Publication Year: 2016
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Abstract:
Just Published!
The definitive clinical virology resource for physicians and clinical laboratory virologists
The clinical virology field is rapidly evolving and, as a result, physicians and clinical laboratory virologists must have a reliable reference tool to aid in their ability to identify and diagnose viral infections to prevent future outbreaks.
In this completely revised edition of the Clinical Virology Manual, Editor in Chief, Michael Loeffelholz, along with Section Editors, Richard Hodinka, Benjamin Pinsky, and Stephen Young, have complied expert perspectives of a renowned team of clinical virology experts and divided these contributions into three sections to provide
- the latest information on the diagnosis of viral infections, including ebola, HIV and Human papillomavirus
- state of the art diagnostic technologies, including next-generation sequencing and nucleic acid amplification methods
- taxonomy of clinically important viruses such as polyomaviruses and zoonotic viruses
This comprehensive reference also includes three appendices with vital information on reference virology laboratories at the Centers for Disease Control and Prevention, state and local public health laboratories, and international reference laboratories and laboratory systems.
Additionally, a new section “Diagnostic Best Practices,” which summarizes recommendations for diagnostic testing, and cites evidence-based guidelines, is included in each viral pathogens chapter.
Clinical Virology Manual, Fifth Edition serves as a reference source to healthcare professionals and laboratorians in providing clinical and technical information regarding viral diseases and the diagnosis of viral infections.
Hardcover, 622 pages, full-color illustrations, index.
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Clinical Virology Manual, Fourth Edition
- Content Type: Reference
- Publication Year: 2009
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Abstract:
A comprehensive and updated volume for the clinical virologist. For over 20 years this manual has remained the definitive source of the latest information and procedures for the physician and the clinical laboratory virologist. This fourth edition includes 34 chapters and two appendices, each thoroughly revised and updated by noted experts. These updates address the modernization of clinical virology and new developments in the field, with a strong emphasis on molecular diagnostics. Importantly, this new edition includes material on several recently described viruses including human metapneumovirus, West Nile virus, bocaviruses, and newer influenza viruses and adenoviruses, plus a broadened focus on papillomaviruses and polyomaviruses.
Divided into two sections, this volume presents essential information for clinicians and laboratory virologists alike. Section I details laboratory procedures for detecting and handling viruses, from specimen requirements and quality assurance to virus detection and identification, from the fundamentals through the latest molecular methods. Section II presents the most current knowledge on the wide range of specific viral pathogens. Finally, two appendices provide valuable and up-to-date information on services provided by federal and state public health virology laboratories.
Hardcover, 623 pages, illustrations, index.
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Clinical Virology, Fourth Edition
- Content Type: Reference
- Publication Year: 2017
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Abstract:
The essential reference of clinical virology
Virology is one of the most dynamic and rapidly changing fields of clinical medicine. For example, sequencing techniques from human specimens have identified numerous new members of several virus families, including new polyomaviruses, orthomyxoviruses, and bunyaviruses.
Clinical Virology, Fourth Edition, has been extensively revised and updated to incorporate the latest developments and relevant research. Chapters written by internationally recognized experts cover novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, organized into two major sections:
- Section 1 provides information regarding broad topics in virology, including immune responses, vaccinology, laboratory diagnosis, principles of antiviral therapy, and detailed considerations of important organ system manifestations and syndromes caused by viral infections.
- Section 2 provides overviews of specific etiologic agents and discusses their biology, epidemiology, pathogenesis of disease causation, clinical manifestations, laboratory diagnosis, and management.
Clinical Virology provides the critical information scientists and health care professionals require about all aspects of this rapidly evolving field.
Hardcover, 1,489 pages, illustrations, index.
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Clinical Virology, Third Edition
- Content Type: Reference
- Publication Year: 2009
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Abstract:
Virology is currently one of the most dynamic and rapidly changing fields of clinical medicine. The new third edition of this essential reference has been extensively revised and updated to incorporate the latest developments and relevant research. Covering novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, Clinical Virology informs scientists and health care professionals about all the medically relevant aspects of this rapidly evolving field.
This landmark volume is organized into two major sections. The first addresses infections and syndromes related to particular organ systems, as well as the fundamentals of modern medical virology. This section includes crucial information on immune responses and vaccinology, diagnostics, antivirals, and the nascent field of gene therapy. The second section provides agent-specific chapters that detail the virology, epidemiology, pathogenesis, clinical manifestations, and prevention and treatment of important viral pathogens. All of the chapters are written by internationally recognized experts.
Hardcover, 725 pages, illustrations, index.
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A Clinician's Dictionary of Pathogenic Microorganisms
- Content Type: Reference
- Authors: James H. Jorgensen, Michael A. Pfaller
- Publication Year: 2004
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Abstract:
Practicing clinicians, trainees, infection control practitioners, and allied health professionals will find the pocket-sized Clinician's Dictionary portable and easy to use. Coverage of pathogenic bacteria, mycobacteria, fungi, viruses, and parasites that affect humans is comprehensive, yet quick and concise. The dictionary provides clinicians with a convenient means of understanding clinical features of the microorganisms they encounter.
Brand new in the field of clinical microbiology, the Clinician's Dictionary features a cross reference of new and old terminology of pathogenic microorganisms and includes material on not only the most common pathogens, but also on those less frequently recovered from patients. No other portable source of information examines species that may be resistant to therapy, defines various infectious syndromes, and affords users easy access to often esoteric organisms. For accurate interpretation of laboratory reports that may include new or unfamiliar organism names, this reference will be the first source of practical information.
Paperback, 273 pages.
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Colonization of Mucosal Surfaces
- Content Type: Monograph
- Publication Year: 2005
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Abstract:
Colonization of Mucosal Surfaces is a state-of-the-art presentation of the opposing evolutionary forces that ultimately determine the health of host organisms and survival of pathogenic microorganisms. As mammalian defenses evolve to protect against infection, pathogens are simultaneously evolving to circumvent new barriers and gain access to valuable host nutrients and energy. Written by experts in the field, this new volume is an in-depth examination of the complex ecosystems of the mammalian mucosa and the successful adaptations of microorganisms that enable them to effectively colonize these surfaces.
First addressing general consideration, Colonization of Mucosal Surfaces then comprehensively covers colonization of the respiratory tract, the gastrointestinal tract, and the genitourinary tract and considers the various organisms present at these surfaces. Aspects of bacterial colonization revealed by the most recent research are also contemplated, including penetration of the mucous layer, innate immune effectors and their subversion, signaling of the host cells by adherence factors, modulation of adherence, phase variation of colonization factors, and regulation of colonization effectors.
Electronic Only, 456 pages, full-color insert, illustrations, index.
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Color Atlas of Medical Bacteriology, Second Edition
- Content Type: Reference
- Publication Year: 2013
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Abstract:
Conceived by a team of authors with decades of classroom and laboraory experience, the Color Atlas of Medical Bacteriology includes more than 730 brilliant, four-color images of common pathogenic bacteria and descriptions of the methods used to identify them, including microscopic and phenotypic characteristics, colonial morphology, and biochemical properties.
Each chapter, organized by pathogen and taxonomic group, begins with a brief introduction that provides a contextual framework for the images. This second edition embraces the latest developments in molecular biology methodology in the diagnostic laboratory with a new chapter examining the breadth and possibilities of these new techniques. Also, in light of the alarming emergence of antibiotic resistance, antimicrobial susceptibiliy testing is addressed in another new chapter. The final chapter on stains, media, and reagents details the most common menthods and biochemical reactions used in the identification of pathogenic bacteria. The book's hundreds of illustrations, of typical stains, colony morphologies, and biochemical reactions of bacteria most frequently encountered in the clinical laboratory, have been thouroughly updated.
A valuable illustrative supplement for lectures and laboratory presentations, this easy-to-use atlas was written for laboratorians, clinicians, students, and anyone interested in the field of diagnostic medical bacteriology.
The Color Atlas of Medical Bacteriology is a good reference book that is fairly complete with wonderful images. It would be a welcome addition to the bookshelves of any teaching institution or clinical microbiology laboratory.
– Clinical Infectious Diseases review of the first edition, written in 2006Hardcover, 366 pages, color illustrations, index.
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Computational Biology: A Hypertextbook
- Content Type: Textbook
- Authors: Scott T. Kelley, Dennis Didulo
- Publication Year: 2018
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Abstract:
An introduction to the world of bioinformatics
Massive increases in computing power and the ability to routinely sequence whole genomes of living organisms have begun to fundamentally alter our understanding of biology, medicine, and agriculture. At the intersection of the growing information and genomics revolutions sits bioinformatics, which uses modern computational power to reveal patterns in biological data sets, especially DNA, RNA, and protein sequences.
Computational Biology: A Hypertextbook, by Scott Kelley and Dennis Didulo, provides a wonderful introduction for anyone who wants to learn the basics of bioinformatics. This book is more than a textbook because of the wealth of online ancillary materials and how the print and electronic components are integrated to form a complete educational resource. Aspects that make Computational Biology: A Hypertextbook a unique and valuable tool for teaching and learning bioinformatics include
- Clear explanations of the basic biology of DNA, RNA, and proteins and how the related bioinformatics algorithms work
- Extensive exercises that enable students to practice with the same bioinformatics applications that are used by scientists worldwide
- Tutorials, sample data sets, and interactive learning tools developed with teachers in mind and field-tested by hundreds of students
- Online tutorials and curated web links that are accurate (instead of frustrating!) and won’t lead to dead ends
- Online resources that work on multiple platforms and electronic devices
Computational Biology: A Hypertextbook is written in an accessible voice, punctuated with humor, and designed to significantly increase computational competencies. Biology and computer science undergraduate and graduate students will thoroughly enjoy learning from this unique hypertextbook, as will anyone with an interest in exploring this burgeoning topic.
Paperback, 210 pages, full-color illustrations, index.
Interested in purchasing the digital version of this title? Click here to buy the book via RedShelf! Click here to buy the book via VitalSource!
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Cryptococcus : From Human Pathogen to Model Yeast
- Content Type: Monograph
- Publication Year: 2011
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Abstract:
Since its first clinical appearance in an 1890s case report, Cryptococcus has dramatically advanced as a human fungal pathogen: it now infects approximately 1 million individuals per year, resulting in more than 600,000 annual mortalities, including one-third of all AIDS-associated deaths.
Featuring more than 100 expert authors from around the world, this book offers the full range of scientific and clinical perspectives needed to create this unique, comprehensive overview of Cryptococcus. It covers both the Cryptococcus neoformans and Cryptococcus gattii species, examining in detail the life cycle, pathophysiology, molecular biology, genetics, genomics, epidemiology, immunology, and clinical management of this encapsulated yeast. Among the 44 chapters, readers will find several in-depth discussions of the C. gattii outbreak that began on Vancouver Island in 1999 and then spread into the mainland of Canada and the United States, causing infections in both humans and animals.
This book’s detailed, thorough reviews of all the latest advances and progress in the field set a new standard for publications dedicated to a single fungal pathogen. While the book is dedicated to Cryptococcus, it does draw analogies to other pathogenic fungi and, more broadly, to other microbial pathogens. Moreover, this volume demonstrates why Cryptococcus has become a model system for the study and understanding of fungal pathogenesis. As a result, molecular biologists, microbiologists, public health officials, epidemiologists, and infectious disease clinicians will all find this clearly written, carefully referenced, and all-inclusive book to be a highly valuable resource.
Hardcover, 620 pages, full-color insert, illustrations, index.
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Cryptococcus neoformans
- Content Type: Monograph
- Authors: Arturo Casadevall, John R. Perfect
- Publication Year: 1998
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Abstract:
The dramatic increase in the incidence of Cryptococcus neoformans infections calls for an up-to-date look at its biology and pathogenesis. This volume provides a comprehensive review of the ecology, epidemiology, pathogenic mechanisms, host immunity, clinical features and diagnostic conditions, and principles of treatment and prevention of this important fungal pathogen.
The only recent monograph on the subject, Cryptococcus neoformans goes beyond textbook chapters and journal articles to provide the most comprehensive, current information on basic science and clinical information relating to this fungus. The authors, investigators who have direct experience with the subject matter, provide objective data as well as interpretations and opinions.
Cryptococcus neoformans, a model organism for the understanding of disseminated mycoses, has become a major concern facing infectious disease physicians and immunocompromised patients. Now this valuable resource provides both experienced investigators and those new to the field of medical mycology an opportunity to review the vast database of knowledge on this major worldwide pathogen.
Electronic only, 541 pages, illustrations, index.
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Cultural Heritage Microbiology : Fundamental Studies in Conservation Science
- Content Type: Monograph
- Editors: Ralph Mitchell, Christopher J. McNamara
- Publication Year: 2010
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Abstract:
Historic and culturally important objects, like all materials, are vulnerable to microbial attack. Over time, microorganisms can affect paint, wood, paper, glass, textiles, metal, wax, stone, polymers, and coatings. Microbial deterioration of heritage materials can be caused by the formation and growth of biofilms or by direct attack by a variety of microorganisms, all of which may be difficult to correct without also damaging the materials themselves. On the other hand, microbial processes can also be adapted to conserve and even restore heritage materials, pointing to the complex nature of microbial interactions with these irreplaceable materials.
Cultural Heritage Microbiology assembles over twenty scientific papers published during the past two decades, each presenting a major advance in some facet of this complex field. These seminal articles, by a wide range of international experts, are grouped by the historic material affected. Each section is introduced by a thorough review, written for this volume, which serves to introduce and synthesize these past studies and to combine them with the latest cutting-edge findings to present the most current state of the field. Extensive references in every chapter and article offer valuable resources for further investigation.
Cultural Heritage Microbiology is ideal for anyone concerned with recognizing and dealing with microbial deterioration of heritage materials. Professionals and students in microbiology, conservation science, archaeology, fine arts, architecture, museum conservation, and other fields will find here the most current knowledge and approaches to preserving cultural heritage objects for generations to come.
Key Features
- Provides a unique, single overview of the seminal literature in conservation microbiology
- Presents the current state of the art along with a synthesis of the major developments over the years
- Represents the findings of leading international experts and pioneers in the field
- Offers conservation scientists and conservators an inclusive view of the heritage conservation field plus extensive resources for further investigation
Hardcover, 348 pages, illustrations, color insert, index.
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The Dark Art of Blood Cultures
- Content Type: Reference
- Editors: Wm. Michael Dunne, Jr., Carey-Ann D. Burnham
- Publication Year: 2017
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Abstract:
Understanding the diagnostic methods necessary to identify bloodstream infections
In the clinical microbiology laboratory, blood is a critical diagnostic sample that, in the majority of cases is sterile (or is it?). However, when microbes gain access to and multiply in the bloodstream, it can result in life-threatening illness including sepsis. Mortality rates from bloodstream infection and sepsis range from 25% to 80%, killing millions of people annually. Blood cultures are a vital technology used in the microbiology laboratory to isolate and identify microbes and predict their response to antimicrobial therapy.
The Dark Art of Blood Cultures, edited by Wm. Michael Dunne, Jr., and Carey-Ann D. Burnham, surveys the entire field of blood culture technology, providing valuable information about every phase of the process, from drawing samples to culture methods to processing positive cultures. The Dark Art of Blood Cultures is organized around several major topics.
- History of blood culture methods. Details the timeline of blood culture methods from manual through automated and describes the technological development of the leading automated blood culture systems (Bactec, BacT/Alert, and VersaTREK).
- Manual and automated blood culture methods. Critiques manual and automated methods for setting up blood cultures for adult and pediatric patients.
- Detection of pathogens directly from blood specimens. Describes currently available CE marked and FDA-cleared commercial tests using both phenotypic and genotypic markers, including their strengths and limitations.
- The workflow of culturing blood. Includes best practices from specimen collection to culture system verification, processing positive cultures for microbe identification and antibiotic susceptibility determination, along with the epidemiology of positive blood cultures and the value of postmortem blood cultures.
- Microorganisms in the blood. Examines the concept of a blood microbiome in healthy and diseased individuals.
The Dark Art of Blood Cultures is a resource that clinicians, laboratorians, lab directors, and hospital administrators will find engaging and extremely useful.
Paperback, 320 pages, full-color illustrations, index.
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Diagnostic Medical Parasitology, Fifth Edition
- Content Type: Reference
- Editor: Lynne S. Garcia
- Publication Year: 2007
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Diagnostic Medical Parasitology, a major reference now in its fifth edition, reviews the dramatic changes that have occurred since the publication of the previous edition. Unique in the field, this revised volume covers human and medical parasitology and provides comprehensive, relevant diagnostic methods in one package.
Authored by an acknowledged expert with many years of practical experience as a medical technologist and as a member of the teaching group at UCLA, the new edition includes significantly updated material and introduces new features. A chapter covering medical case histories has been added as well as many spectacular figures. Summary tables have been augmented and appropriately updated. Newly recognized parasites are incorporated, new and improved diagnostic methods are discussed, relevant regulatory requirements are covered, and expanded sections detailing artifact material and histological diagnosis are included.
The logical organization and the format of previous editions have been retained in the fifth edition of Diagnostic Medical Parasitology. The first section of the book presents complete information on individual parasites and provides information related to life cycles, morphology, disease presentations in the immunocompetent and compromised patient, diagnosis, treatment, epidemiology, and prevention. The second section offers clear and complete diagnostic procedures for use in the clinical microbiology laboratory, describing traditional and rapid techniques used for parasite detection and identification.
Electronic only, 1,202 pages, illustrations, glossary, index.
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Diagnostic Medical Parasitology, Sixth Edition
- Content Type: Reference
- Author: Lynne S. Garcia
- Publication Year: 2016
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The essential reference for selecting, using, and interpreting methods and results related to human parasitic infections
This major work by Lynne Garcia, a recognized authority on diagnostic parasitology, has been completely updated to include the dramatic changes that have occurred in the field of diagnostic medical parasitology over the past decade. Diagnostic Medical Parasitology, Sixth Edition, features newly recognized human parasites, improved diagnostic techniques defined by new regulatory requirements, implementation of testing based on molecular techniques, expanded tables and color photographs, and the latest information on parasitic infections.
Diagnostic Medical Parasitology contains two sections within this single volume. The first provides clear, concise diagnostic procedures for clinical laboratory use, including ordering and collection recommendations, techniques for parasite recovery and identification that are relevant throughout the world. This section also thoroughly examines the pros and cons of various diagnostic options, including extensive report comments for result clarification and enhancement.
The second section presents comprehensive discussions of common and uncommon individual human parasites. It provides information related to life cycle, morphology, and clinical disease in both the immunocompetent and immunocompromised patient including diagnosis, treatment, epidemiology, and prevention. There are also expanded sections on artifacts, case histories, and histologic findings that provide discussion and tips related to potential diagnostic problems. Both book sections feature extensive color illustrations related to each technique and parasite presented, as well as expanded color plates of human parasites.
Diagnostic Medical Parasitology is a unique and valuable resource for microbiologists and clinical laboratory scientists/bench technologists in diagnostic laboratories and academic settings, infectious disease physicians, pathologists, health care specialists, and public health professionals.
"Diagnostic Medical Parasitology is a critical reference for every microbiology laboratory. It covers all aspects of human medical parasitology and provides detailed, comprehensive, relevant diagnostic methods in one volume. The color images are fantastic for use in assisting you in the identification of parasites. To ensure that your microbiology personnel are employing practical quality procedures in the area of parasitology, you need this book!"
Susan E. Sharp, Ph.D., ABMM, FAAM, Director, Regional Microbiology and Molecular Infectious Diseases Laboratories, Kaiser Permanente, Department of Pathology
Hardcover, 1388 pages, full-color illustrations, index.
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Diagnostic Microbiology of the Immunocompromised Host
- Content Type: Monograph
- Editors: Randall T. Hayden, Karen C. Carroll, Yi-Wei Tang, Donna M. Wolk
- Publication Year: 2009
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Over the past twenty-five years, the number of patients with compromised immune systems has grown astronomically. High-risk patients such as these require a unique set of healthcare solutions that take into consideration everything from the etiology and degree of immune suppression to the individual patient’s nutritional status. This comprehensive volume, assembled by a group of distinguished authors, examines a wide range of approaches and challenges to infectious disease diagnostics for immunocompromised patients.
Divided into four sections, the book takes a multifaceted approach to the detection and characterization of infections encountered in this high-risk patient group. The first section provides a broad explanation of the causes of immune suppression, the populations at risk for infections, and the various kinds of infections. The next section addresses crucial laboratory diagnostic methods for individual pathogens, while the third section takes a more systematic perspective on the affected organs in immunocompromised patients. The volume concludes with a discussion of future trends in the field. The material is clearly summarized in practical, user-friendly procedures that can be applied to everyday patient care challenges.
This book will be an indispensable reference for laboratory professionals, infectious disease physicians, oncologists, and other healthcare providers who care for immunocompromised patients.
Electronic Only, 479 pages, full-color insert, illustrations, index.
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Diagnostic Microbiology of the Immunocompromised Host, Second Edition
- Content Type: Monograph
- Editors: Randall T. Hayden, Donna M. Wolk, Karen C. Carroll, Yi-Wei Tang
- Publication Year: 2016
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Strategies for providing optimal care to this high-risk patient group
The immunocompromised patient population is increasing throughout the world. Major advances in transplantation techniques have expanded access to lifesaving therapies and improved outcomes in these high-risk populations. An understanding of the biology of these infections, host conditions, and the limitations of technologies used to detect and quantify such pathogens is critical to optimal care.
This new edition of Diagnostic Microbiology of the Immunocompromised Host covers all aspects of state-of-the-art diagnostics for infectious complications in the immunocompromised patient. Editors Randall Hayden, Karen Carroll, Yi-Wei Tang, and Donna Wolk assembled the contributions of a team of preeminent authors to discuss a broad range of topics, including
- relevant aspects of host biology, antineoplastic, and transplantation techniques and the basis of immunosuppressive conditions ranging from diabetes to age-related immunosuppression
- approaches, interpretations, and limitations of laboratory diagnosis of infections by a wide range of specific etiologic agents
- laboratory diagnosis of infections of specific organ systems, such as respiratory tract infections, gastrointestinal tract infections, and central nervous system infections
- special topics such as prosthetic devices and catheters, healthcare acquired infections, and morphologic considerations (anatomic pathology)
- future diagnostic technologies and their potential impact on the field
Diagnostic Microbiology of the Immunocompromised Host is a resource for laboratory medicine specialists, pathologists, technologists, students, and clinical care professionals who are involved or interested in the care of the immunocompromised host.
Hardcover, 794 pages, full-color illustrations, index.
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The DNA Provirus : Howard Temin's Scientific Legacy
- Content Type: Monograph
- Editors: Geoffrey M. Cooper, Rayla Greenberg Temin, Bill Sugden
- Publication Year: 1995
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ASM Press is proud to publish this volume in honor of Nobel Prize winning virologist, Howard Temin. Temin's pioneering scientific achievements in elucidating the fundamentals of retroviruses laid the ground work for our present understanding of the molecular basis of both cancer and HIV. Few advances in contemporary molecular biology have been as significant or as controversial as Howard Temin's initial proposal of the DNA provirus hypothesis that turned molecular biology's central dogma on its head.
Electronic Only, 356 pages, photos.
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DNA Repair and Mutagenesis, Second Edition
- Content Type: Reference
- Authors: C. Friedberg Errol, C. Walker Graham, Siede Wolfram, D. Wood Richard, A. Schultz Roger, Ellenberger Tom
- Publication Year: 2006
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Featuring more than 10,000 references and a text lavishly complemented by over 700 illustrations, DNA Repair and Mutagenesis, 2nd Edition, is a timely update to the original edition published in 1995. The addition of three new authors, including an expert in the field of structural biology, ensures a comprehensive review of the most current research in diverse subject areas. An ideal textbook for advanced undergraduate and graduate students, the book is also an essential resource for all scientists researching cellular responses to DNA damage.
Completely reorganized, the new edition presents a significant overhaul of the existing chapters and introduces important new material, reflective of the major changes and developments that have occurred in the field over the last decade. As with the first edition, this new volume presents the field within a strong historical framework and all aspects of biological responses to DNA damage are detailed.
The book consists of 30 chapters divided into five main parts, covering: sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage. Basic principles are appropriately stressed; however, the book focuses on the significant progress to date and future research directions.
Hardcover, 1,118 pages, two-color throughout with full-color insert, illustrations, index.
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The Elusive Malaria Vaccine : Miracle or Mirage?
- Content Type: Trade
- Author: Irwin W. Sherman
- Publication Year: 2009
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Chronicling a 100-year quest, this book tells the fascinating story of the hunt for the still-elusive malaria vaccine. Its clear, engaging style makes the book accessible to a general audience and brings to life all the drama of the hunt, celebrating the triumphs and documenting the failures. The author captures the controversies, missteps, wars of words, stolen ideas, and clashes of ego as researchers around the world compete to develop the first successful malaria vaccine.
The Elusive Malaria Vaccine: Miracle or Mirage? is based on author Irwin W. Sherman’s thorough investigation of the scientific literature as well as his first-hand interviews with today’s pioneers in malaria vaccine research. As a result, the book offers remarkable insights into the keys to a successful malaria vaccine and the obstacles hindering its development.
Malaria is one of humankind’s greatest killers, currently afflicting some 300 to 500 million people. Moreover, malaria infections have begun to spread and surge in places previously free from the disease. With the book’s easy-to-follow coverage of such topics as immunity, immunology, recombinant DNA, and monoclonal antibodies, readers gain a new understanding of the disease itself, the importance of microbe hunters, and the need for responsible leadership to face the challenges that lie ahead in the battle against malaria.
Hardcover, 391 pages, index.
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Emerging Diseases of Animals
- Content Type: Monograph
- Editors: Corrie Brown, Carole Bolin
- Publication Year: 2000
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Abstract:
While it is widely recognized that diseases in humans are emerging at an unprecedented rate, an often overlooked phenomenon is that the same issue is present in animal populations, where new diseases are occurring at an even faster rate than in humans.
This important new volume provides an in-depth review of various emerging diseases in animals and highlights the importance of veterinary medicine in the control of emerging diseases. It discusses the need for an awareness of emerging diseases in animals in preparation for emerging diseases in humans and offers an understanding of the serious negative consequences of animal diseases on human populations, including zoonotic potential, ecological impact, and compromising of the food chain.
Electronic only, 310 pages, illustrations, index.
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Emerging Infections 1
- Content Type: Monograph
- Editors: W. Micheal Scheld, Donald Armstrong, James M. Hughes
- Publication Year: 1998
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This book is the first of an annual series of books which will be based on ICAAC Symposia on Emerging Infections. The editors are in the forefront of the scientific and clinical communities dealing with emerging pathogens. Each chapter is written by an expert in the field and will cover basic science as well as clinical topics. This book and the series will be valuable and popular for a wide range of people working in the fields of infectious diseases, internal medicine, and clinical microbiology.
Paperback, 277 pages, illustrations, index.
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Emerging infections 10
- Content Type: Monograph
- Editors: W. Michael Scheld, James M. Hughes, Richard J. Whitley
- Publication Year: 2016
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Essential resource for the fight against emerging infectious diseases
Incidences such as the 2014 Ebola epidemic in West Africa and the 2015 appearance of Zika in Brazil provide dramatic evidence of the continued ability of microbes to emerge, spread, adapt, and threaten global health. The challenge facing infectious disease specialists and public health professionals is to improve and find new diagnostic, therapeutic, and prevention strategies.
The editors of the 10th installment of the Emerging Infections series have compiled the perspectives of leading infectious disease experts into 22 chapters that provide important updates on a broad range of emerging and reemerging bacterial, viral, parasitic, and fungal infectious diseases in the United States and globally. In addition to focusing on MERS, Ebola virus disease, chikungunya, and Zika virus disease, Emerging Infections 10 explores the global threat of antimicrobial resistance in reviews on carbapenem-resistant Enterobacteriaceae, multiply-resistant gonococcal infections, non-typhoidal Salmonella infections, and artemisinin-resistant Plasmodium falciparum malaria. Topics include both recently- and long-recognized diseases that pose challenges for the clinical, laboratory, research, public health, and animal health communities.
Emerging Infections 10 presents new and emerging strategies to prevent, control, and eradicate infectious diseases and guides readers to the primary literature where they can explore individual topics in greater depth. This book is a valuable reference for professionals in microbiology, epidemiology, public health, and clinical and veterinary medicine.
“The renowned editors and the authors they enlisted teach us about microbial threats in our rapidly changing world. From frogs to people, from viruses to fungi, they detail compelling stories about urgent problems and suggest solutions. Emerging Infections 10 is an education at the front-lines of a perennial struggle.”
—Martin J. Blaser, M.D., Director, Human Microbiome Program, New York Universitym, Author of Missing Microbes
“In keeping with the longstanding tradition of this series, the 10th edition of Emerging Infections continues with timely updates of the newest information on the ever changing landscape of new infections of public health importance.”
—David C. Hooper, MD, Professor of Medicine, Harvard Medical School; Chief, Infection Control Unit and Associate Chief, Division of Infectious Diseases, Massachusetts General Hospital
Hardcover, 462 pages, full-color illustrations, index.
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Emerging Infections 2
- Content Type: Monograph
- Editors: W. Michael Scheld, William A. Craig, James M. Hughes
- Publication Year: 1998
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The second volume in an annual series of books based on ICAAC Symposia, Emerging Infections 2 provides a complete and updated discussion of new and emerging infectious diseases, covering both basic science and clinical topics. Written by experts in the field, this new book offers broad coverage on topics ranging from prions and viruses to bacteria and helminths. It also includes chapters on food borne diseases in the 21st century, concerns in blood safety, and strategies for addressing emerging infections on a global scale. A foreword is written by U. S. Surgeon General Dr. David Satcher.
This book and the series will be valuable to a wide range of people working in microbiology, infectious diseases, epidemiology, public health, and medicine.
The print version of this title is no longer available.
Electronic, 350 pages, illustrations, index.
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Emerging Infections 3
- Content Type: Monograph
- Editors: W. Michael Scheld, William A. Craig, James M. Hughes
- Publication Year: 1999
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Emerging Infections 3 is the third of an annual series of books based on ICAAC Symposia on Emerging Infections. It provides a complete and updated discussion of new and emerging infectious diseases, covering both basic science and clinical topics. The editors are in the forefront of the scientific and clinical communities dealing with emerging pathogens. This book and the series will be valuable to a wide range of people working in microbiology, infectious diseases, epidemiology, public health, and clinical medicine.
This book is no longer available in print.
Electronic book, 260 pages, illustrations, index.
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Emerging Infections 4
- Content Type: Monograph
- Editors: W. Michael Scheld, William A. Craig, James M. Hughes
- Publication Year: 2000
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Emerging Infections 4 is the fourth of an annual series of books based on ICAAC Symposia on Emerging Infections. It provides a complete and updated discussion of new and emerging infectious diseases, covering both basic science and clinical topics. The editors are in the forefront of the scientific and clinical communities dealing with emerging pathogens. This book and the series will be valuable to a wide range of people working in microbiology, infectious diseases, epidemiology, public health, and clinical medicine.
Electronic Only, 218 pages, illustrations, index.
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Emerging Infections 5
- Content Type: Monograph
- Editors: W. Michael Scheld, William A. Craig, James M. Hughes
- Publication Year: 2001
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Emerging Infections 5 is the fifth of an annual series of books based on ICAAC Symposia on Emerging Infections. It provides a complete and updated discussion of new and emerging infectious diseases, covering both basic science and clinical topics. The editors are in the forefront of the scientific and clinical communities dealing with emerging pathogens. This book and the series will be valuable to a wide range of people working in microbiology, infectious diseases, epidemiology, public health, and clinical medicine.
Electronic Only, 264 pages, illustrations, index.
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Emerging Infections 6
- Content Type: Monograph
- Editors: W. Michael Scheld, Barbara E. Murray, James M. Hughes
- Publication Year: 2004
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Emerging Infections 6 is the sixth of a series of books based on ICAAC Symposia on Emerging Infections. It provides a complete and updated discussion of new and emerging infectious diseases, covering both basic science and clinical topics. The editors are in the forefront of the scientific and clinical communities dealing with emerging pathogens. This book and the series will be valuable to a wide range of people working in microbiology, infectious diseases, epidemiology, public health, and clinical medicine.
Electronic Only, 210 pages, illustrations, index.
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Emerging Infections 7
- Content Type: Monograph
- Editors: W. Michael Scheld, David C. Hooper, James M. Hughes
- Publication Year: 2007
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This new volume is the seventh in a series of books based on ICAAC Symposia on Emerging Infections. It offers an updated review of new and emerging infectious diseases, including Avian Influenza (H5N1), Severe Acute Respiratory Syndrome (SARS), West Nile fever, and many others. The editors are experts in their respective fields of research and are active in the scientific and clinical communities that deal with emerging pathogens. The Emerging Infections series is a valuable resource for a wide range of people working in microbiology, Infectious diseases, epidemiology, public health, and clinical medicine.
Electronic Only, 381 pages, illustrations, index.
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Emerging Infections 8
- Content Type: Monograph
- Editors: W. Michael Scheld, Scott M. Hammer, James M. Hughes
- Publication Year: 2008
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This new volume in the series is based on ICAAC and IDSA Symposia on Emerging Infections. It offers an updated review of new and emerging pathogens and infectious diseases, including novel non-SARS coronaviruses, community-associated methicillin-resistant Staphylococcus aureus, pertussis, extensively drug-resistant tuberculosis, and many others. The editors are experts in their respective fields of research and are active in the scientific and clinical communities that deal with emerging pathogens. The Emerging Infections series is a valuable resource for a wide range of people working in microbiology, infectious diseases, epidemiology, public health, and clinical medicine.
Electronic Only, 470 pages, illustrations, index.
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Emerging Infections 9
- Content Type: Monograph
- Editors: W. Michael Scheld, M. Lindsay Grayson, James M. Hughes
- Publication Year: 2010
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Since 1995, the program committees of the Interscience Conference on Antimicrobial Agents and Chemotherapy and the Infectious Diseases Society of America have organized sessions on current and emerging infectious disease threats during their annual meetings. These sessions explore strategies for the prevention and control of bacteria, viruses, fungi, and parasites that can harm public health. Chapters in Emerging Infections 9 are based on recent sessions, focusing on a broad range of infectious agents that pose challenges for the clinical, laboratory, research, public health, and animal health communities.
Emerging Infections 9 reflects the diversity of infectious agent threats in the 21st century. Some of these agents have been only recently discovered, such as the Acanthamoebapolyphagamimivirus. Others are known pathogens presenting new challenges, such as human adenovirus 14. Some infectious agents discussed in the book are currently regional threats, whereas others affect populations around the world. However, every regional threat is potentially a global threat, an issue explored in detail in this edition. Moreover, the book�s discussion of the One World�One Health Initiative underscores the need for a global, multidisciplinary approach in investigating, developing, and implementing solutions.
Each chapter has been contributed by one or more leading experts in infectious diseases, offering perspectives from basic and clinical research, epidemiology, and public health. Despite progress in the prevention and control of infectious diseases during the past several decades, many challenges remain at the same time as new challenges emerge. Emerging Infection 9�s coverage of current and emerging threats is therefore essential for anyone involved in the fight against infectious diseases, including professionals in microbiology, epidemiology, public health, and clinical and veterinary medicine.
Hardcover, 379 pages, full-color insert, illustrations, index.
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Enterobacter sakazakii
- Content Type: Monograph
- Editors: Jeffrey M. Farber, Stephen J. Forsythe, Michael P. Doyle
- Publication Year: 2008
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Enterobacter sakazakii causes a range of infections that can be fatal or cause lifelong debilitation in newborns. Because the organism affects the youngest and most vulnerable group of our population, the issue has become a critical concern for the food industry. This volume brings together all recent findings and knowledge on this unique pathogen and addresses a wide range of issues, including taxonomy, detection and identification, virulence potential, monitoring and control during infant formula production, and regulatory issues.
Knowledge on Enterobacter sakazakii has been changing quickly within the last couple of years. By bringing together the leading experts in this critical field, this book makes an invaluable contribution to the future of food safety. Chapters explain the details of infant formula production; the organism’s interaction with neonatal intestinal systems, epidemiology, and mechanisms of pathogenicity; and the effects of the disease. Additionally, this volume points to larger issues within food production, food regulation, and inspection. For many years to come, this book will be a necessary and useful reference tool for regulators, policymakers, and academics involved with the issue of contaminated powdered infant formula and this organism.
Electronic Only, 271 pages, illustrations, index.
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The Enterobacteria, Second Edition
- Content Type: Monograph
- Authors: J. Michael Janda, Sharon L. Abbott
- Publication Year: 2006
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The Enterobacteria, 2nd Edition provides a comprehensive examination of current research on every genus in the family Enterobacteriaceae. A host of diagnostic tables, reference charts, color plates, and various other laboratory resources, this revised reference is an important source of information from microbiologists, lab directors, pathologists, and infectious disease specialists.
The Enterobacteria, 2nd Edition presents complete medical information on each genus, including taxonomy, epidemiology, infectious disease spectrum, identification, pathogenicity, and antimicrobial susceptibility. Additionally, this new volume presents unique information on procedures and protocols for identification of atypical or unusual variants of each species. Select new features of the second edition are use of the genome sequence as a means of identification and classification, coverage of the reclassified genus Plesiomonas, and a brand-new appendix containing differential biochemical tables.
Electronic only, 411 pages, full-color insert, illustrations, index.
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The Enterococci : Pathogenesis, Molecular Biology, and Antibiotic Resistance
- Content Type: Monograph
- Editors: Michael S. Gilmore, Don B. Clewell, Patrice Courvalin, Gary M. Dunny, Barbara E. Murray, Louis B. Rice
- Publication Year: 2002
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Enterococci are among the vanguard of antibiotic-resistant bacteria both because they are intrinsically unaffected by antibiotics and because they have acquired resistance genes to counter the antibiotics that once were effective.
This new volume offers a comprehensive primary text on enterococci and covers the pathogenesis of infection, molecular biology, and antibiotic resistance. The Enterococci will be of great value to those dealing with the consequences of antibiotic-resistant infection, those actively engaged in enterococcal research, and those searching for a scientific basis for public policy decisions.
Electronic Only, 439 pages, illustrations, index.
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Enterohemorrhagic Escherichia coli and Other Shiga Toxin-Producing E. coli
- Content Type: Monograph
- Editors: Vanessa Sperandio, Carolyn J. Hovde
- Publication Year: 2015
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Whether contracted through contaminated food or a trip to the petting zoo, disease-causing E. coli is a major human health threat
Most Escherichia coli strains live harmlessly in the intestines of healthy humans and animals, but virulent strains—the enterohemorrhagic E. coli (EHEC) and certain Shiga toxin–producing E. coli (STEC)—cause life-threatening infections, with young children and the elderly most at risk. EHEC and STEC are easily transmitted through contaminated water or food and, more rarely, through contact between animals and people. Thus, controlling outbreaks of these pathogens is a concern for the infectious disease community and the food industry.
Covering a diverse array of topics, including microbial pathogenesis, disease pathophysiology, food safety, genetic analysis, veterinary microbiology, epidemiology, and environmental microbiology, Enterohemorrhagic Escherichia coli and Other Shiga Toxin-Producing E. coli presents the most current, relevant research overview from a multidisciplinary, international group of expert authors concerned with tracking, deciphering, and dealing with the diseases caused by EHEC and STEC.
Editors Vanessa Sperandio and Carolyn J. Hovde have updated and expanded the scope of the previous edition, Escherichia coli O157:H7 and Other Shiga Toxin-Producing E. coli Strains. Useful as a textbook for advanced courses in microbiology, food safety, infectious disease, or microbial pathogenesis, this new volume is also a valuable reference for research scientists, clinicians, health professionals, policy makers, and food safety professionals.
"This volume, edited by two experts in the field, Vanessa Sperandio and Carolyn Hovde, encompasses the current state of knowledge of the epidemiology and pathogenesis of EHEC and defines the challenges to improved disease control. Comprehensive and timely, this is a must read for those engaged in E. coli research."
—Guy H. Palmer, Regents Professor and Director of the Paul G. Allen School for Global Animal Health, Washington State University, Pullman
Vanessa Sperandio is a Professor in the Departments of Microbiology and Biochemistry at the University of Texas Southwestern Medical Center. Her research investigates chemical, stress, and nutritional signaling at the interface among the mammalian host, beneficial microbiota, and invading pathogens. A fellow of the American Academy of Microbiology and the 2015 recipient of the ASM Eli Lilly and Company-Elanco Research Award, Dr. Sperandio serves on the editorial boards of mBio, Infection and Immunity, Journal of Bacteriology, and Gut Pathogens.
Carolyn J. Hovde is a University Distinguished Professor who has served as the Idaho NIH INBRE Director since 2006. Dr. Hovde’s laboratory studies E. coli O157:H7 with a primary focus on understanding the relationship between this human pathogen and its silent reservoir, healthy cattle. A Fellow of the American Association for the Advancement of Science and winner of the ASM Carski Foundation Distinguished Undergraduate Teaching Award, she is President of the National Association of IDeA Principal Investigators (NAIPI).
Hardcover, 570 pages, full-color illustrations, index.
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Environmental Microbe-Metal Interactions
- Content Type: Monograph
- Editor: Derek R. Lovley
- Publication Year: 2000
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Abstract:
Although it has been commonly believed that non-biological processes control the fate of metals in the environment, it is becoming increasingly apparent that microorganisms have a major impact on metal chemistry. This new book, the first in more than 10 years to examine environmental microbe-metal interactions, summarizes the current understanding of the interaction of microorganisms and metals in the environment. It offers the reader a comprehensive overview of the field and a basis for improved models of metal cycling.
Environmental Microbe-Metal Interactions makes clear the significance of these interactions and provides clues for areas of further investigation. It is valuable reading for scientists with an interest in environmental microbiology, microbial diversity and ecology, and geochemistry.
Electronic only, 408 pages, illustrations, index.
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Environmental Microbial Forensics
- Content Type: Monograph
- Editors: Raúl J. Cano, Gary A. Toranzos
- Publication Year: 2018
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Microbiology in the service of law and public safety.
Forensic scientists use tools from the natural sciences and engineering to analyze physical evidence. Such evidence might be at a crime scene, a bioterrorism event, at the site of an oil spill or chemical discharge, or when in pursuit of a foodborne infectious disease. Increasingly, microbes are serving as some of that physical evidence. The DNA of isolated microorganisms is being subjected to whole-genome sequencing, while the metagenomes of microbiomes found in the environment are now routinely sequenced and analyzed. Databases of microbial genomes are growing rapidly, and probing those databases with powerful bioinformatics tools and other analytical techniques enables comparative microbial genomics to be applied to forensic analysis.
The powerful genomics tools available today are being applied to forensic analysis of microorganisms in a diverse array of situations. Many of these methods and applications are presented in Environmental Microbial Forensics, edited by Gary Toranzos and Raúl Cano. This fascinating book includes detailed discussions on
- Solving crimes using environmental microbial forensics. Soil microbiomes are being analyzed to evaluate cadaver decomposition, identify clandestine graves, and serve as trace evidence. Plant pathogens are monitored as potential agroterrorism agents, have been used as herbicides sprayed on drug crops, and been sequenced and identified when determining liability for the unintentional spread of phytopathogens. Bioterrorism attacks are often solved by using genomics analysis of the pathogen to trace it to its source, as was done in solving the Bacillus anthracis United States mail attacks in 2001.
- Examining human history by studying ancient microbial DNA. Paleomicrobiology, or the study of ancient microbes (and especially of their DNA), is revealing the epidemiology of ancient infectious diseases, tracing ancient disease migration patterns, and using coprolites (petrified feces) as a window into the gut microbiomes—and by extension, the dietary habits—of our human ancestors. Victims of epidemics, such as the major plague outbreaks in Europe and Asia, who were buried in “catastrophe cemeteries,” are telling tales about the strains of Yersinia pestis responsible for their demise.
- Tracking the culprits of public health crimes to their sources. Source tracking outbreaks of foodborne diseases, monitoring water quality, and expanding our knowledge of host-pathogen interactions are all benefiting from molecular forensic analyses. Molecular microbial forensics provides insights into the evolutionary changes of host-pathogen interactions. To maintain water quality and minimize the impacts of foodborne diseases, methods like qPCR, microarray analysis, and high-throughput sequencing allow scientists to subtype microbial culprits and track them to their source.
- Handling microbial samples, choosing molecular methods, and running statistical analyses. Microbial forensic methods require stringent quality control procedures from sample collection through data collection. The Microbiome Quality Control project, for example, is a recent effort to evaluate methods for probing microbiomes. Bioinformatics programs are now available that accept multiple microbial genome datasets as input and assist in reconstructing transmission pathways of an outbreak. In microbial forensic situations, likelihood and Bayesian approaches are perhaps the better statistical methods to choose when it comes time to analyze the data.
Electronic only, 285 pages, full-color illustrations.
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Environmental Microbiology
- Content Type: Textbook
- Author: Alan H. Varnam
- Publication Year: 2000
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Abstract:
Help your students save on textbooks! Email us and receive a coupon to share with your students for 20% off of the purchase of a print copy.
Photographer: Malcolm G. Evans
Microorganisms play a major role in the geobiology and geochemistry of the planet, forming the basic stage in the food chain, and thus sustaining the existence of higher evolutionary life. The continuing interaction between these living organisms and the environment, combined with their exploitation by man, shape the material world.
Over the past few years our understanding has increased considerably by means of new technology and the emergence of paradigms which enable the microbiologist to view the microbial world, and its significance to life, with new eyes. The book reflects these exciting developments by combining the basics of science with the most up-to-date new material. It will be valuable as a textbook and reference guide for students and professionals in microbiology, freshwater and marine biology, soil science, environmental biology, and planning.
Paperback, 160 pages, 4-color throughout, index.
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Enzyme-Mediated Resistance to Antibiotics : Mechanisms, Dissemination, and Prospects for Inhibition
- Content Type: Monograph
- Editors: Robert A. Bonomo, Marcelo E. Tolmasky
- Publication Year: 2007
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Antibiotic-resistant bacteria, or “superbugs,” present an increasingly deadly threat to human health. The World Health Organization estimates that resistant bacteria now account for about 60% of nosocomial infections; the CDC estimates that of the ca. 60,000 deaths each year due to nosocomial infection, some 14,000 are the result of antibiotic-resistant bacteria. With chapters from the world’s leading researchers and scholars in this field, Enzyme-Mediated Resistance to Antibiotics is a vital and timely overview of this critical subject.
Bacteria have evolved a wealth of different ways to resist the action of antibiotics, as well as to transfer these resistance traits once acquired. An important number of these mechanisms are mediated by enzymatic processes. Beta-Lactamases aminoglycoside-modifying enzymes are thoroughly discussed in this volume, as well as other enzymatic mechanisms that result in resistance. The different ways bacteria share resistance determinants, both vertically and horizontally, are also discussed. Finally, chapters offer strategies to control the dissemination of resistance genes and to combat these highly versatile inactivating enzymes.
This comprehensive volume will find a wide audience in researchers working in bacterial pathogenesis, enzymology, molecular microbiology, and antibiotic development. It will be indispensable for clinical research laboratories, hospitals, medical schools, and applied and pharmaceutical research laboratories.
Hardcover, 357 pages, four-color insert, illustrations, index.
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Evolution of Microbial Pathogens
- Content Type: Monograph
- Editors: H. Steven Seifert, Victor J. DiRita
- Publication Year: 2006
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Abstract:
This new volume offers an up-to-date examination of the evolution of microbial pathogenesis, capitalizing on the explosion of knowledge in the field and the recent advent of microbial genome sequencing. Written by experts in the field of microbial evolution and microbial pathogenesis, Evolution of Microbial Pathogens is a valuable reference for laboratory directors, postdoctoral fellows, and upper-level undergraduate and graduate students.
Composed of three main sections, the book provides comprehensive coverage with a dual focus on pathogenesis and methods used to study evolution. The first section emphasizes broad themes of evolution and examines the process of studying evolution. The second section provides examples of how problems that are common to various pathogens have been solved by evolution. The remaining chapters cover a selection of well-studied classes of pathogens and the evolution of their disease-causing mechanisms. Each section opens with an overview written by an investigator with broad expertise in the subject area, and individual chapters offer a list of key points to summarize the material covered.
Hardcover, 355 pages, illustrations, index.
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Evolutionary Biology of Bacterial and Fungal Pathogens
- Content Type: Monograph
- Publication Year: 2008
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Abstract:
This innovative volume introduces clinical microbiologists, infectious disease specialists, epidemiologists, medical professionals, and public health researchers to the importance and influence of evolutionary outcomes. Humans experience countless interactions with the microbial world; our biology is intertwined with the biology of microbes; we co-evolve with them. Understanding this evolutionary reality provides a powerful tool to integrate and synthesize a huge amount of heterogeneous information from a variety of fields studying human biology.
Written by an international team of distinguished researchers and practitioners, the volume’s 49 chapters cover the relationship between microbial evolution and human biology from many perspectives. The first section illustrates the evolutionary biology of microbial-human interactions, considering the effect of human-driven changes. The second section analyzes evolutionary genetics involved in microbial variation and adaptation, from microbial genome to mobile elements as plasmids or integrons. The third section deals with evolutionary microbial responses to antibiotics, the major anthropogenic factor altering our interactions with microbes. Finally, the last three sections systematically analyze the evolution of pathogenesis in gram-negative and gram-positive bacteria, and fungi. These chapters convey the impact of evolution on microbe-human interactions, and how that influences infectious diseases. This information will stimulate an evolutionary orientation in the daily interpretation of facts that are observed in the laboratory and the hospital.
Hardcover, 622 pages, full-color insert, illustrations, index.
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Exposure : A Guide to Sources of Infections
- Content Type: Reference
- Author: Dieter A. Stürchler
- Publication Year: 2006
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Abstract:
Exposure: a Guide to Sources of Infections is a single reference source for clinicians, public health professionals, epidemiologists, and clinical microbiologists working to identify infectious diseases agents. From prions to parasites, this unique new volume offers comprehensive coverage of infections and infectious agents and provides a good starting point for compiling a thorough patient exposure history and initiating the appropriate laboratory testing.
The infectious diseases detailed in Exposure are organized by major exposure groups and subgroups, and the book offers an international scope of coverage. Up-to-date information on sources of infections, transmission risks, and potential infectious agents is provided. A system of icons used throughout the book facilitates easy use of the book in time-sensitive situations. Infection risks for individuals, at-risk groups, the community at large, and outbreak situations are documented.
Exposure features an alphabetical listing of infectious agents that examines modes of spread, risks, and the impact of infections. Additionally, the book includes an overview table that reviews the taxonomy of the most agents that infect humans and a select number of agents that infect animals. Appendixes provide an exposure checklist, a glossary, and a list of acronyms used in the book.
Electronic Only, 894 pages, illustrations, index.
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The Fecal Bacteria
- Content Type: Monograph
- Editors: Michael J. Sadowsky, Richard L. Whitman
- Publication Year: 2011
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Abstract:
The Fecal Bacteria offers a balanced, integrated discussion of fecal bacteria and their presence and ecology in the intestinal tract of mammals, in the environment, and in the food supply. This new volume covers their use in examining and assessing water quality in order to offer protection from illnesses related to swimming in or ingesting contaminated water, in addition to discussing their use in engineering considerations of water quality, modeling, monitoring, and regulations. Fecal bacteria are additionally used as indicators of contamination of ready-to-eat foods and fresh produce. The intestinal environment, the microbial community structure of the gut microbiota, and the physiology and genomics of this broad group of microorganisms are explored in the book.
With contributions from an internationally recognized group of experts, the book integrates medicine, public health, environmental, and microbiological topics in order to provide a unique, holistic understanding of fecal bacteria. Moreover, it shows how the latest basic science and applied research findings are helping to solve problems and develop effective management strategies. For example, readers will discover how the latest tools and molecular approaches have led to our current understanding of fecal bacteria and enabled us to improve human health and water quality.
The Fecal Bacteria is recommended for microbiologists, clinicians, animal scientists, engineers, environmental scientists, food safety experts, water quality managers, and students. It will help them better understand fecal bacteria and use their knowledge to protect human and environmental health. They can also apply many of the techniques and molecular tools discussed in this book to the study of a broad range of microorganisms in a variety of habitats.
Hardcover, 315 pages, four-color insert, illustrations, index.