Understanding Transcription, Translation, and the Effect of Mutations

  • Author: Linda Fisher1
    Affiliations: 1: Associate Professor of Biology and Microbiology, University of Michigan-Dearborn
  • Citation: Linda Fisher. 2001. Understanding transcription, translation, and the effect of mutations.
  • Publication Date : July 2001
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In this activity, students will practice identifying a translation open reading frame in the context of a nucleotide sequence and recognizing the effects that mutations of various types have on the resulting polypeptide product. This can be done using short DNA "microsequences" written specifically for this activity, student- or instructor-written sequences, or actual published gene sequences (e.g., from GenBank).

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