1887

Facilitating Growth through Frustration: Using Genomics Research in a Course-Based Undergraduate Research Experience

    Authors: David Lopatto1, Anne G. Rosenwald2,*, Justin R. DiAngelo3, Amy T. Hark4, Matthew Skerritt5, Matthew Wawersik6, Anna K. Allen7, Consuelo Alvarez8, Sara Anderson9, Cindy Arrigo10, Andrew Arsham11, Daron Barnard12, Christopher Bazinet13, James E. J. Bedard14, Indrani Bose15, John M. Braverman16, Martin G. Burg17, Rebecca C. Burgess18, Paula Croonquist19, Chunguang Du20, Sondra Dubowsky21, Heather Eisler22, Matthew A. Escobar23, Michael Foulk24, Emily Furbee25, Thomas Giarla26, Rivka L. Glaser27, Anya L. Goodman28, Yuying Gosser29, Adam Haberman30, Charles Hauser31, Shan Hays32, Carina E. Howell33, Jennifer Jemc34, M. Logan Johnson35, Christopher J. Jones36, Lisa Kadlec37, Jacob D. Kagey38, Kimberly L. Keller39, Jennifer Kennell40, S. Catherine Silver Key41, Adam J. Kleinschmit42, Melissa Kleinschmit42, Nighat P. Kokan43, Olga Ruiz Kopp44, Meg M. Laakso45, Judith Leatherman46, Lindsey J. Long47, Mollie Manier48, Juan C. Martinez-Cruzado49, Luis F. Matos50, Amie Jo McClellan51, Gerard McNeil52, Evan Merkhofer53, Vida Mingo54, Hemlata Mistry55, Elizabeth Mitchell21, Nathan T. Mortimer56, Debaditya Mukhopadhyay57, Jennifer Leigh Myka58, Alexis Nagengast59, Paul Overvoorde60, Don Paetkau61, Leocadia Paliulis62, Susan Parrish63, Mary Lai Preuss64, James V. Price44, Nicholas A. Pullen65, Catherine Reinke66, Dennis Revie67, Srebrenka Robic68, Jennifer A. Roecklein-Canfield69, Michael R. Rubin70, Takrima Sadikot71, Jamie Siders Sanford72, Maria Santisteban73, Kenneth Saville74, Stephanie Schroeder64, Christopher D. Shaffer75, Karim A. Sharif76, Diane E. Sklensky77, Chiyedza Small78, Mary Smith79, Sheryl Smith80, Rebecca Spokony81, Aparna Sreenivasan82, Joyce Stamm83, Rachel Sterne-Marr84, Katherine C. Teeter85, Justin Thackeray86, Jeffrey S. Thompson87, Stephanie Toering Peters88, Melanie Van Stry89, Norma Velazquez-Ulloa90, Cindy Wolfe91, James Youngblom92, Brian Yowler93, Leming Zhou94, Janie Brennan95, Jeremy Buhler96, Wilson Leung75, Laura K. Reed97, Sarah C. R. Elgin75
    VIEW AFFILIATIONS HIDE AFFILIATIONS
    Affiliations: 1: Center for Teaching, Learning and Assessment, Grinnell College, Grinnell, IA 50112, USA; 2: Biology, Georgetown University, Washington, DC 20057, USA; 3: Division of Science, Penn State Berks, Reading, PA 19610, USA; 4: Biology, Muhlenberg College, Allentown, PA 18104, USA; 5: Science, SUNY Corning Community College, Corning, NY 14830, USA; 6: Biology, College of William and Mary, Williamsburg, VA 23187, USA; 7: Biology, Howard University, Washington, DC 20059, USA; 8: Biology, Longwood University, Farmville, VA 23909, USA; 9: Biosciences, Minnesota State University Moorhead, Moorhead, MN 56563, USA; 10: Biology, New Jersey City University, Jersey City, NJ 07305, USA; 11: Biology, Bemidji State University, Bemidji, MN 56601, USA; 12: Biology, Worcester State University, Worcester, MA 01602, USA; 13: Biological Sciences, St. John’s University, Queens, NY 11439, USA; 14: Biology, University of the Fraser Valley, Abbotsford, BC, V2S 7M8, Canada; 15: Biology, Western Carolina University, Cullowhee, NC 28723, USA; 16: Biology, Saint Joseph’s University, Philadelphia, PA 19131, USA; 17: Biomedical Sciences and Cell & Molecular Biology, Grand Valley State University, Allendale, MI 49401, USA; 18: Biological Sciences, Stevenson University, Owings Mills, MD 21117, USA; 19: Biology, Anoka-Ramsey Community College, Coon Rapids, MN 55433, USA; 20: Biology, Montclair State University, Montclair, NJ 07043, USA; 21: Biology, McLennan Community College, Waco, TX 76708, USA; 22: Biology, University of the Cumberlands, Williamsburg, KY 40769, USA; 23: Biological Sciences, California State University San Marcos, CA 92096, USA; 24: Biology, Mercyhurst University, Erie, PA 16546, USA; 25: Biology, Washington and Jefferson College, Washington, PA 15301, USA; 26: Biology, Siena College, Loudonville, NY 12211, USA; 27: Biological Sciences, Stevenson University, Owings Mills, MD 21117, USA; 28: Chemistry and Biochemistry, California Polytechnic State University, San Luis Obispo, CA 93407, USA; 29: Student Research and Scholarship, City College CUNY, New York, NY 10031, USA; 30: Biology, University of San Diego, San Diego, CA 92110, USA; 31: Biology, St. Edward’s University, Austin, TX 78704, USA; 32: Biology, Western Colorado University, Gunnison, CO 81231, USA; 33: Biological Sciences, Lock Haven University, Lock Haven, PA 17745, USA; 34: Biology, Loyola University Chicago, Chicago, IL 60660, USA; 35: Biology, Notre Dame College, South Euclid, OH 44121, USA; 36: Biological Sciences, Moravian College, Bethlehem, PA 18018, USA; 37: Biology, Wilkes University, Wilkes-Barre, PA 18766, USA; 38: Biology, University of Detroit Mercy, Detroit, MI 48221, USA; 39: Biology, William Woods University, Fulton, MO 65251, USA; 40: Biology, Vassar College, Poughkeepsie, NY 12604, USA; 41: Biological and Biomedical Sciences, North Carolina Central University, Durham, NC 27707, USA; 42: Natural and Applied Science, University of Dubuque, Dubuque, IA 52001, USA; 43: Natural Sciences, Cardinal Stritch University, Milwaukee, WI 53217, USA; 44: Biology, Utah Valley University, Orem, UT 84058, USA; 45: Biology, Eastern University, St. Davids, PA 19087, USA; 46: Biological Sciences, University of Northern Colorado, Greeley, CO 80639, USA; 47: Biology, Oklahoma Christian University, Oklahoma City, OK 73136, USA; 48: Biological Sciences, George Washington University, Washington, DC 20052, USA; 49: Biología, University of Puerto Rico at Mayagüez, Mayagüez, PR 00680, USA; 50: Biology, Eastern Washington University, Cheney, WA 99004, USA; 51: Science and Mathematics, Bennington College, Bennington, VT 05201, USA; 52: Biology, York College / CUNY, Jamaica, NY 11451, USA; 53: Natural Sciences, Mount Saint Mary College, Newbergh, NY 12550, USA; 54: Biology, Columbia College, Columbia, SC 29203, USA; 55: Biology and Biochemistry, Widener University, Chester, PA 19013, USA; 56: Biological Sciences, Illinois State University, Normal, IL 61790, USA; 57: Molecular Biology, Biochemistry, and Bioinformatics, Towson University, Towson, MD 21252, USA; 58: Biology, Gateway Community and Technical College, Florence, KY 41042, USA; 59: Chemistry and Biochemistry, Widener University, Chester, PA 19013, USA; 60: Biology, Macalester College, St. Paul, MN 55105, USA; 61: Biology, Saint Mary’s College, Notre Dame, IN 46556, USA; 62: Biology, Bucknell University, Lewisburg, PA 17837, USA; 63: Biology, McDaniel College, Westminster, MD 21157, USA; 64: Biological Sciences, Webster University, St. Louis, MO 63119, USA; 65: Biological Sciences, University of Northern Colorado, Greeley, CO 80639, USA; 66: Biology, Linfield College, McMinnville, OR 97128, USA; 67: Biology, California Lutheran University, Thousand Oaks, CA 91360, USA; 68: Biology, Agnes Scott College, Decatur, GA 30030, USA; 69: Chemistry, Simmons College, Boston, MA 02115, USA; 70: Biology, University of Puerto Rico at Cayey, Cayey, PR 00736, USA; 71: Biology, Washburn University, Topeka, KS 66621, USA; 72: Biology, Ohio Northern University, Ada, OH 45810, USA; 73: Biology, University of North Carolina at Pembroke, Pembroke, NC 28372, USA; 74: Biology, Albion College, Albion, MI 49224, USA; 75: Biology, Washington University in St. Louis, St. Louis, MO 63130, USA; 76: Biology, Massasoit Community College, Brockton, MA 02302, USA; 77: Biology, Lane College, Jackson, TN 38301, USA; 78: Biology, Medgar Evers College, CUNY, Brooklyn, NY 11225, USA; 79: Biology, North Carolina A & T State University, Greensboro, NC 27411, USA; 80: Biology, Arcadia, University, Glenside, PA 19038, USA; 81: Natural Sciences, Baruch College, CUNY, New York, NY 10010, USA; 82: Biology, School of Natural Sciences, California State University, Monterey Bay, Seaside, CA 93950, USA; 83: Biology, University of Evansville, Evansville, IN 47722, USA; 84: Biology, Siena College, Loudonville, NY 12211, USA; 85: Biology, Northern Michigan University, Marquette, MI 49855, USA; 86: Biology, Clark University, Worcester, MA 01610, USA; 87: Biology, Denison University, Granville, OH 43023, USA; 88: Biology, Wartburg College, Waverly, IA 50677, USA; 89: Biology, Lane College, Jackson, TN 38301, USA; 90: Biology, Lewis & Clark College, Portland, OR 97219, USA; 91: Biology, Kentucky Wesleyan College, Owensboro, KY 42301, USA; 92: Biological Sciences, California State University Stanislaus, Turlock, CA 95382, USA; 93: Biology, Grove City College, Grove City, PA 16127, USA; 94: Health Information Management, University of Pittsburgh, Pittsburgh, PA 15213, USA; 95: Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA; 96: Computer Science and Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA; 97: Biological Sciences, University of Alabama Tuscaloosa, AL 35487, USA
    AUTHOR AND ARTICLE INFORMATION AUTHOR AND ARTICLE INFORMATION
    • Received 16 October 2019 Accepted 23 January 2020 Published 28 February 2020
    • ©2020 Author(s). Published by the American Society for Microbiology

    • [open-access] This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-NoDerivatives 4.0 International license (https://creativecommons.org/licenses/by-nc-nd/4.0/ and https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode), which grants the public the nonexclusive right to copy, distribute, or display the published work.
    • †Supplemental materials available at http://asmscience.org/jmbe
    • *Corresponding author. Mailing address: Biology Department, Georgetown University, 306 Regents Hall, 37th and O Sts, NW, Washington, DC 20057. Phone: 202-687-5997. E-mail [email protected]
    Source: J. Microbiol. Biol. Educ. February 2020 vol. 21 no. 1 doi:10.1128/jmbe.v21i1.2005
MyBook is a cheap paperback edition of the original book and will be sold at uniform, low price.
  • XML
    263.17 Kb
  • HTML
    106.33 Kb
  • PDF
    1.28 MB

    Abstract:

    A hallmark of the research experience is encountering difficulty and working through those challenges to achieve success. This ability is essential to being a successful scientist, but replicating such challenges in a teaching setting can be difficult. The Genomics Education Partnership (GEP) is a consortium of faculty who engage their students in a genomics Course-Based Undergraduate Research Experience (CURE). Students participate in genome annotation, generating gene models using multiple lines of experimental evidence. Our observations suggested that the students’ learning experience is continuous and recursive, frequently beginning with frustration but eventually leading to success as they come up with defendable gene models. In order to explore our “formative frustration” hypothesis, we gathered data from faculty via a survey, and from students via both a general survey and a set of student focus groups. Upon analyzing these data, we found that all three datasets mentioned frustration and struggle, as well as learning and better understanding of the scientific process. Bioinformatics projects are particularly well suited to the process of iteration and refinement because iterations can be performed quickly and are inexpensive in both time and money. Based on these findings, we suggest that a dynamic of “formative frustration” is an important aspect for a successful CURE.

References & Citations

1. Dewey J 1933 How we think: a restatement of the relation of reflective thinking to the educative process Boston Houghton Mifflin Boston, MA
2. Csikszentmihalyi M 1990 Flow: the psychology of optimal experience Harper Perennial New York, NY
3. Amsel A 1958 The role of frustrative nonreward in noncontinuous reward situations Psych Bull 55 2 102 119 10.1037/h0043125 http://dx.doi.org/10.1037/h0043125
4. Amsel A 1992 Frustration theory: many years later Psych Bull 112 3 396 399 10.1037/0033-2909.112.3.396 http://dx.doi.org/10.1037/0033-2909.112.3.396
5. Arkes HR, Garske JP 1982 Psychological theories of motivation Thomson Brooks/Cole
6. Bjork RA 1994 Memory and metamemory considerations in the training of humans 185 205 Metcalfe J, Shimura AP Metacognition: knowing about knowing MIT Press Cambridge, MA
7. Metcalfe J 2011 Desirable difficulties and studying in the region of proximal learning in successful remembering and successful forgetting Psychology Press New York, NY
8. Jaber LZ, Hammer D 2016 Engaging in science: a feeling for the discipline J Learn Sci 25 2 156 202 10.1080/10508406.2015.1088441 http://dx.doi.org/10.1080/10508406.2015.1088441
9. Arango-Munoz S, Michaelian K 2014 Epistemic feelings, epistemic emotions: review and introduction to the focus section Philos Inq 2 1 97 122
10. Rivard K, Faste H 2012 How learning works in design education: educating for creative awareness through formative reflexivity 298 307 DIS ’12: Proceedings of the Designing Interactive Systems Conference ACM 10.1145/2317956.2318002 http://dx.doi.org/10.1145/2317956.2318002
11. Dweck CS, Leggett EL 1988 A social-cognitive approach to motivation and personality Psych Rev 95 2 256 273 10.1037/0033-295X.95.2.256 http://dx.doi.org/10.1037/0033-295X.95.2.256
12. Dweck CS 2016 Mindset: the new psychology of success Ballantine Books New York, NY
13. Holmes NG, Day J, Park AHK, Bonn DA, Roll I 2014 Making the failure more productive: scaffolding the invention process to improve inquiry behaviors and outcomes in invention activities Instr Sci 42 4 523 528 10.1007/s11251-013-9300-7 http://dx.doi.org/10.1007/s11251-013-9300-7
14. Kapur M 2008 Productive failure Cogn Instr 26 3 379 424 10.1080/07370000802212669 http://dx.doi.org/10.1080/07370000802212669
15. Washauer HK 2015 Productive struggle in middle school mathematics classrooms J Math Teacher Educ 18 4 375 400 10.1007/s10857-014-9286-3 http://dx.doi.org/10.1007/s10857-014-9286-3
16. Nagda BA, Gregerman SR, Jonides J, von Hippel W, Lerner JS 1998 Undergraduate student–faculty research partnerships affect student retention Rev Higher Educ 22 1 55 72 10.1353/rhe.1998.0016 http://dx.doi.org/10.1353/rhe.1998.0016
17. Rodenbusch SE, Hernandez PR, Simmons SL, Dolan EL 2016 Early engagement in course-based research increases graduation rates and completion of science, engineering, and mathematics degrees CBE Life Sci Educ 15 2 1 10 10.1187/cbe.16-03-0117 http://dx.doi.org/10.1187/cbe.16-03-0117
18. Eagan MK Jr, Hurtado S, Chang MJ, Garcia GA, Herrera FA, Garibay JC 2013 Making a difference in science education: the impact of undergraduate research programs American Educ Res J 50 4 683 713 10.3102/0002831213482038 http://dx.doi.org/10.3102/0002831213482038
19. Walcott RL, Corso PS, Rodenbusch SE, Dolan EL 2018 Benefit-cost analysis of undergraduate education programs: an example analysis of the freshman research initiative CBE Life Sci Educ 17 1 rm1 10.1187/cbe.17-06-0114 29378752 6007785 http://dx.doi.org/10.1187/cbe.17-06-0114
20. Bangera G, Brownell SE 2014 Course-based undergraduate research experiences can make scientific research more inclusive CBE Life Sci Educ 13 4 602 606 10.1187/cbe.14-06-0099 25452483 4255347 http://dx.doi.org/10.1187/cbe.14-06-0099
21. National Academies of Sciences, Engineering, and Medicine 2015 Integrating discovery-based research into the undergraduate curriculum: report of a convocation The National Academies Press Washington, DC
22. National Academies of Sciences, Engineering, and Medicine 2017 Undergraduate research experiences for STEM students: successes, challenges, and opportunities The National Academies Press Washington, DC
23. Elgin SCR, Hauser C, Holzen TM, Jones C, Kleinschmit A, Leatherman J Genomics Education Partnership 2017 The GEP crowd-sourcing big data analysis with undergraduates Trends Genet 33 2 81 85 10.1016/j.tig.2016.11.004 http://dx.doi.org/10.1016/j.tig.2016.11.004
24. Wei CA, Woodin T 2011 Undergraduate research experiences in biology: alternatives to the apprenticeship model CBE Life Sci Educ 10 2 123 131 10.1187/cbe.11-03-0028 21633057 3105915 http://dx.doi.org/10.1187/cbe.11-03-0028
25. Lopatto D, Alvarez C, Barnard D, Chandrasekaran C, Chung HM, Du C, Eckdahl T, Goodman AL, Hauser C, Jones CJ, Kopp OR, Kuleck GA, McNeil G, Morris R, Myka JL, Nagengast A, Overvoorde PJ, Poet JL, Reed K, Regisford G, Revie D, Rosenwald A, Saville K, Shaw M, Skuse GR, Smith C, Smith M, Spratt M, Stamm J, Thompson JS, Wilson BA, Witkowski C, Youngblom J, Leung W, Shaffer CD, Buhler J, Mardis E, Elgin SC 2008 Undergraduate research. Genomics Education Partnership Science 322 5902 684 685 10.1126/science.1165351 18974335 2953277 http://dx.doi.org/10.1126/science.1165351
26. Shaffer CD, Alvarez C, Bailey C, Barnard D, Bhalla S, Chandrasekaran C, Chandrasekaran V, Chung HM, Dorer DR, Du C, Eckdahl TT, Poet JL, Frohlich D, Goodman AL, Gosser Y, Hauser C, Hoopes LL, Johnson D, Jones CJ, Kaehler M, Kokan N, Kopp OR, Kuleck GA, McNeil G, Moss R, Myka JL, Nagengast A, Morris R, Overvoorde PJ, Shoop E, Parrish S, Reed K, Regisford EG, Revie D, Rosenwald AG, Saville K, Schroeder S, Shaw M, Skuse G, Smith C, Smith M, Spana EP, Spratt M, Stamm J, Thompson JS, Wawersik M, Wilson BA, Youngblom J, Leung W, Buhler J, Mardis ER, Lopatto D, Elgin SC 2010 The genomics education partnership: successful integration of research into laboratory classes at a diverse group of undergraduate institutions CBE Life Sci Educ 9 1 55 69 10.1187/09-11-0087 20194808 2830162 http://dx.doi.org/10.1187/09-11-0087
27. Shaffer CD, Alvarez CJ, Bednarski AE, Dunbar D, Goodman AL, Reinke C, Rosenwald AG, Wolyniak MJ, Bailey C, Barnard D, Bazinet C, Beach DL, Bedard JE, Bhalla S, Braverman J, Burg M, Chandrasekaran V, Chung HM, Clase K, Dejong RJ, Diangelo JR, Du C, Eckdahl TT, Eisler H, Emerson JA, Frary A, Frohlich D, Gosser Y, Govind S, Haberman A, Hark AT, Hauser C, Hoogewerf A, Hoopes LL, Howell CE, Johnson D, Jones CJ, Kadlec L, Kaehler M, Silver Key SC, Kleinschmit A, Kokan NP, Kopp O, Kuleck G, Leatherman J, Lopilato J, Mackinnon C, Martinez-Cruzado JC, McNeil G, Mel S, Mistry H, Nagengast A, Overvoorde P, Paetkau DW, Parrish S, Peterson CN, Preuss M, Reed LK, Revie D, Robic S, Roecklein-Canfield J, Rubin MR, Saville K, Schroeder S, Sharif K, Shaw M, Skuse G, Smith CD, Smith MA, Smith ST, Spana E, Spratt M, Sreenivasan A, Stamm J, Szauter P, Thompson JS, Wawersik M, Youngblom J, Zhou L, Mardis ER, Buhler J, Leung W, Lopatto D, Elgin SC 2014 A course-based research experience: how benefits change with increased investment in instructional time CBE Life Sci Educ 13 1 111 130 10.1187/cbe-13-08-0152 24591510 3940452 http://dx.doi.org/10.1187/cbe-13-08-0152
28. Leung W, Shaffer CD, Chen EJ, Quisenberry TJ, Ko K, Braverman JM, Giarla TC, Mortimer NT, Reed LK, Smith ST, Robic S, McCartha SR, Perry DR, Prescod LM, Sheppard ZA, Saville KJ, McClish A, Morlock EA, Sochor VR, Stanton B, Veysey-White IC, Revie D, Jimenez LA, Palomino JJ, Patao MD, Patao SM, Himelblau ET, Campbell JD, Hertz AL, McEvilly MF, Wagner AR, Youngblom J, Bedi B, Bettincourt J, Duso E, Her M, Hilton W, House S, Karimi M, Kumimoto K, Lee R, Lopez D, Odisho G, Prasad R, Robbins HL, Sandhu T, Selfridge T, Tsukashima K, Yosif H, Kokan NP, Britt L, Zoellner A, Spana EP, Chlebina BT, Chong I, Friedman H, Mammo DA, Ng CL, Nikam VS, Schwartz NU, Xu TQ, Burg MG, Batten SM, Corbeill LM, Enoch E, Ensign JJ, Franks ME, Haiker B, Ingles JA, Kirkland LD, Lorenz-Guertin JM, Matthews J, Mittig CM, Monsma N, Olson KJ, Perez-Aragon G, Ramic A, Ramirez JR, Scheiber C, Schneider PA, Schultz DE, Simon M, Spencer E, Wernette AC, Wykle ME, Zavala-Arellano E, McDonald MJ, Ostby K, Wendland P, DiAngelo JR, Ceasrine AM, Cox AH, Docherty JEB, Gingras RM, Grieb SM, Pavia MJ, Personius CL, Polak GL, Beach DL, Cerritos HL, Horansky EA, Sharif KA, Moran R, Parrish S, Bickford K, Bland J, Broussard J, Campbell K, Deibel KE, Forka R, Lemke MC, Nelson MB, O’Keeffe C, Ramey SM, Schmidt L, Villegas P, Jones CJ, Christ SL, Mamari S, Rinaldi AS, Stity G, Hark AT, Scheuerman M, Silver Key SC, McRae BD, Haberman AS, Asinof S, Carrington H, Drumm K, Embry T, McGuire R, Miller-Foreman D, Rosen S, Safa N, Schultz D, Segal M, Shevin Y, Svoronos P, Vuong T, Skuse G, Paetkau DW, Bridgman RK, Brown CM, Carroll AR, Gifford FM, Gillespie JB, Herman SE, Holtcamp KL, Host MA, Hussey G, Kramer DM, Lawrence JQ, Martin MM, Niemiec EN, O’Reilly AP, Pahl OA, Quintana G, Rettie EAS, Richardson TL, Rodriguez AE, Rodriguez MO, Schiraldi L, Smith JJ, Sugrue KF, Suriano LJ, Takach KE, Vasquez AM, Velez X, Villafuerte EJ, Vives LT, Zellmer VR, Hauke J, Hauser CR, Barker K, Cannon L, Parsamian P, Parsons S, Wichman Z, Bazinet CW, Johnson DE, Bangura A, Black JA, Chevee V, Einsteen SA, Hilton SK, Kollmer M, Nadendla R, Stamm J, Fafara-Thompson AE, Gygi AM, Ogawa EE, Van Camp M, Kocsisova Z, Leatherman JL, Modahl CM, Rubin MR, Apiz-Saab SS, Arias-Mejias SM, Carrion-Ortiz CF, Claudio-Vazquez PN, Espada-Green DM, Feliciano-Camacho M, Gonzalez-Bonilla KM, Taboas-Arroyo M, Vargas-Franco D, Montañez-Gonzalez R, Perez-Otero J, Rivera-Burgos M, Rivera-Rosario FJ, Eisler HL, Alexander J, Begley SK, Gabbard D, Allen RJ, Aung WY, Barshop WD, Boozalis A, Chu VP, Davis JS, Duggal RN, Franklin R, Gavinski K, Gebreyesus H, Gong HZ, Greenstein RA, Guo AD, Hanson C, Homa KE, Hsu SC, Huang Y, Huo L, Jacobs S, Jia S, Jung KL, Wai-Chee Kong S, Kroll MR, Lee BM, Lee PF, Levine KM, Li AS, Liu C, Liu MM, Lousararian AP, Lowery PB, Mallya AP, Marcus JE, Ng PC, Nguyen HP, Patel R, Precht H, Rastogi S, Sarezky JM, Schefkind A, Schultz MB, Shen D, Skorupa T, Spies NC, Stancu G, Vivian Tsang HM, Turski AL, Venkat R, Waldman LE, Wang K, Wang T, Wei JW, Wu DY, Xiong DD, Yu J, Zhou K, McNeil GP, Fernandez RW, Menzies PG, Gu T, Buhler J, Mardis ER, Elgin SCR 2017 Retrotransposons are the major contributors to the expansion of the Drosophila ananassae Muller F element G3 (Bethesda) 7 8 2439 2460 10.1534/g3.117.040907 http://dx.doi.org/10.1534/g3.117.040907
29. Leung W, Shaffer CD, Reed LK, Smith ST, Barshop W, Dirkes W, Dothager M, Lee P, Wong J, Xiong D, Yuan H, Bedard JE, Machone JF, Patterson SD, Price AL, Turner BA, Robic S, Luippold EK, McCartha SR, Walji TA, Walker CA, Saville K, Abrams MK, Armstrong AR, Armstrong W, Bailey RJ, Barberi CR, Beck LR, Blaker AL, Blunden CE, Brand JP, Brock EJ, Brooks DW, Brown M, Butzler SC, Clark EM, Clark NB, Collins AA, Cotteleer RJ, Cullimore PR, Dawson SG, Docking CT, Dorsett SL, Dougherty GA, Downey KA, Drake AP, Earl EK, Floyd TG, Forsyth JD, Foust JD, Franchi SL, Geary JF, Hanson CK, Harding TS, Harris CB, Heckman JM, Holderness HL, Howey NA, Jacobs DA, Jewell ES, Kaisler M, Karaska EA, Kehoe JL, Koaches HC, Koehler J, Koenig D, Kujawski AJ, Kus JE, Lammers JA, Leads RR, Leatherman EC, Lippert RN, Messenger GS, Morrow AT, Newcomb V, Plasman HJ, Potocny SJ, Powers MK, Reem RM, Rennhack JP, Reynolds KR, Reynolds LA, Rhee DK, Rivard AB, Ronk AJ, Rooney MB, Rubin LS, Salbert LR, Saluja RK, Schauder T, Schneiter AR, Schulz RW, Smith KE, Spencer S, Swanson BR, Tache MA, Tewilliager AA, Tilot AK, VanEck E, Villerot MM, Vylonis MB, Watson DT, Wurzler JA, Wysocki LM, Yalamanchili M, Zaborowicz MA, Emerson JA, Ortiz C, Deuschle FJ, DiLorenzo LA, Goeller KL, Macchi CR, Muller SE, Pasierb BD, Sable JE, Tucci JM, Tynon M, Dunbar DA, Beken LH, Conturso AC, Danner BL, DeMichele GA, Gonzales JA, Hammond MS, Kelley CV, Kelly EA, Kulich D, Mageeney CM, McCabe NL, Newman AM, Spaeder LA, Tumminello RA, Revie D, Benson JM, Cristostomo MC, DaSilva PA, Harker KS, Jarrell JN, Jimenez LA, Katz BM, Kennedy WR, Kolibas KS, LeBlanc MT, Nguyen TT, Nicolas DS, Patao MD, Patao SM, Rupley BJ, Sessions BJ, Weaver JA, Goodman AL, Alvendia EL, Baldassari SM, Brown AS, Chase IO, Chen M, Chiang S, Cromwell AB, Custer AF, DiTommaso TM, El-Adaimi J, Goscinski NC, Grove RA, Gutierrez N, Harnoto RS, Hedeen H, Hong EL, Hopkins BL, Huerta VF, Khoshabian C, LaForge KM, Lee CT, Lewis BM, Lydon AM, Maniaci BJ, Mitchell RD, Morlock EV, Morris WM, Naik P, Olson NC, Osterloh JM, Perez MA, Presley JD, Randazzo MJ, Regan MK, Rossi FG, Smith MA, Soliterman EA, Sparks CJ, Tran DL, Wan T, Welker AA, Wong JN, Sreenivasan A, Youngblom J, Adams A, Alldredge J, Bryant A, Carranza D, Cifelli A, Coulson K, Debow C, Delacruz N, Emerson C, Farrar C, Foret D, Garibay E, Gooch J, Heslop M, Kaur S, Khan A, Kim V, Lamb T, Lindbeck P, Lucas G, Macias E, Martiniuc D, Mayorga L, Medina J, Membreno N, Messiah S, Neufeld L, Nguyen SF, Nichols Z, Odisho G, Peterson D, Rodela L, Rodriguez P, Rodriguez V, Ruiz J, Sherrill W, Silva V, Sparks J, Statton G, Townsend A, Valdez I, Waters M, Westphal K, Winkler S, Zumkehr J, DeJong RJ, Hoogewerf AJ, Ackerman CM, Armistead IO, Baatenburg L, Borr MJ, Brouwer LK, Burkhart BJ, Bushhouse KT, Cesko L, Choi TY, Cohen H, Damsteegt AM, Darusz JM, Dauphin CM, Davis YP, Diekema EJ, Drewry M, Eisen ME, Faber HM, Faber KJ, Feenstra E, Felzer-Kim IT, Hammond BL, Hendriksma J, Herrold MR, Hilbrands JA, Howell EJ, Jelgerhuis SA, Jelsema TR, Johnson BK, Jones KK, Kim A, Kooienga RD, Menyes EE, Nollet EA, Plescher BE, Rios L, Rose JL, Schepers AJ, Scott G, Smith JR, Sterling AM, Tenney JC, Uitvlugt C, VanDyken RE, VanderVennen M, Vue S, Kokan NP, Agbley K, Boham SK, Broomfield D, Chapman K, Dobbe A, Dobbe I, Harrington W, Ibrahem M, Kennedy A, Koplinsky CA, Kubricky C, Ladzekpo D, Pattison C, Ramirez RE Jr, Wande L, Woehlke S, Wawersik M, Kiernan E, Thompson JS, Banker R, Bartling JR, Bhatiya CI, Boudoures AL, Christiansen L, Fosselman DS, French KM, Gill IS, Havill JT, Johnson JL, Keny LJ, Kerber JM, Klett BM, Kufel CN, May FJ, Mecoli JP, Merry CR, Meyer LR, Miller EG, Mullen GJ, Palozola KC, Pfeil JJ, Thomas JG, Verbofsky EM, Spana EP, Agarwalla A, Chapman J, Chlebina B, Chong I, Falk IN, Fitzgibbons JD, Friedman H, Ighile O, Kim AJ, Knouse KA, Kung F, Mammo D, Ng CL, Nikam VS, Norton D, Pham P, Polk JW, Prasad S, Rankin H, Ratliff CD, Scala V, Schwartz NU, Shuen JA, Xu A, Xu TQ, Zhang Y, Rosenwald AG, Burg MG, Adams SJ, Baker M, Botsford B, Brinkley B, Brown C, Emiah S, Enoch E, Gier C, Greenwell A, Hoogenboom L, Matthews JE, McDonald M, Mercer A, Monsma N, Ostby K, Ramic A, Shallman D, Simon M, Spencer E, Tomkins T, Wendland P, Wylie A, Wolyniak MJ, Robertson GM, Smith SI, DiAngelo JR, Sassu ED, Bhalla SC, Sharif KA, Choeying T, Macias JS, Sanusi F, Torchon K, Bednarski AE, Alvarez CJ, Davis KC, Dunham CA, Grantham AJ, Hare AN, Schottler J, Scott ZW, Kuleck GA, Yu NS, Kaehler MM, Jipp J, Overvoorde PJ, Shoop E, Cyrankowski O, Hoover B, Kusner M, Lin D, Martinov T, Misch J, Salzman G, Schiedermayer H, Snavely M, Zarrasola S, Parrish S, Baker A, Beckett A, Belella C, Bryant J, Conrad T, Fearnow A, Gomez C, Herbstsomer RA, Hirsch S, Johnson C, Jones M, Kabaso R, Lemmon E, Vieira CM, McFarland D, McLaughlin C, Morgan A, Musokotwane S, Neutzling W, Nietmann J, Paluskievicz C, Penn J, Peoples E, Pozmanter C, Reed E, Rigby N, Schmidt L, Shelton M, Shuford R, Tirasawasdichai T, Undem B, Urick D, Vondy K, Yarrington B, Eckdahl TT, Poet JL, Allen AB, Anderson JE, Barnett JM, Baumgardner JS, Brown AD, Carney JE, Chavez RA, Christgen SL, Christie JS, Clary AN, Conn MA, Cooper KM, Crowley MJ, Crowley ST, Doty JS, Dow BA, Edwards CR, Elder DD, Fanning JP, Janssen BM, Lambright AK, Lane CE, Limle AB, Mazur T, McCracken MR, McDonough AM, Melton AD, Minnick PJ, Musick AE, Newhart WH, Noynaert JW, Ogden BJ, Sandusky MW, Schmuecker SM, Shipman AL, Smith AL, Thomsen KM, Unzicker MR, Vernon WB, Winn WW, Woyski DS, Zhu X, Du C, Ament C, Aso S, Bisogno LS, Caronna J, Fefelova N, Lopez L, Malkowitz L, Marra J, Menillo D, Obiorah I, Onsarigo EN, Primus S, Soos M, Tare A, Zidan A, Jones CJ, Aronhalt T, Bellush JM, Burke C, DeFazio S, Does BR, Johnson TD, Keysock N, Knudsen NH, Messler J, Myirski K, Rekai JL, Rempe RM, Salgado MS, Stagaard E, Starcher JR, Waggoner AW, Yemelyanova AK, Hark AT, Bertolet A, Kuschner CE, Parry K, Quach M, Shantzer L, Shaw ME, Smith MA, Glenn O, Mason P, Williams C, Key SC, Henry TC, Johnson AG, White JX, Haberman A, Asinof S, Drumm K, Freeburg T, Safa N, Schultz D, Shevin Y, Svoronos P, Vuong T, Wellinghoff J, Hoopes LL, Chau KM, Ward A, Regisford EG, Augustine L, Davis-Reyes B, Echendu V, Hales J, Ibarra S, Johnson L, Ovu S, Braverman JM, Bahr TJ, Caesar NM, Campana C, Cassidy DW, Cognetti PA, English JD, Fadus MC, Fick CN, Freda PJ, Hennessy BM, Hockenberger K, Jones JK, King JE, Knob CR, Kraftmann KJ, Li L, Lupey LN, Minniti CJ, Minton TF, Moran JV, Mudumbi K, Nordman EC, Puetz WJ, Robinson LM, Rose TJ, Sweeney EP, Timko AS, Paetkau DW, Eisler HL, Aldrup ME, Bodenberg JM, Cole MG, Deranek KM, DeShetler M, Dowd RM, Eckardt AK, Ehret SC, Fese J, Garrett AD, Kammrath A, Kappes ML, Light MR, Meier AC, O’Rouke A, Perella M, Ramsey K, Ramthun JR, Reilly MT, Robinett D, Rossi NL, Schueler MG, Shoemaker E, Starkey KM, Vetor A, Vrable A, Chandrasekaran V, Beck C, Hatfield KR, Herrick DA, Khoury CB, Lea C, Louie CA, Lowell SM, Reynolds TJ, Schibler J, Scoma AH, Smith-Gee MT, Tuberty S, Smith CD, Lopilato JE, Hauke J, Roecklein-Canfield JA, Corrielus M, Gilman H, Intriago S, Maffa A, Rauf SA, Thistle K, Trieu M, Winters J, Yang B, Hauser CR, Abusheikh T, Ashrawi Y, Benitez P, Boudreaux LR, Bourland M, Chavez M, Cruz S, Elliott G, Farek JR, Flohr S, Flores AH, Friedrichs C, Fusco Z, Goodwin Z, Helmreich E, Kiley J, Knepper JM, Langner C, Martinez M, Mendoza C, Naik M, Ochoa A, Ragland N, Raimey E, Rathore S, Reza E, Sadovsky G, Seydoux MI, Smith JE, Unruh AK, Velasquez V, Wolski MW, Gosser Y, Govind S, Clarke-Medley N, Guadron L, Lau D, Lu A, Mazzeo C, Meghdari M, Ng S, Pamnani B, Plante O, Shum YK, Song R, Johnson DE, Abdelnabi M, Archambault A, Chamma N, Gaur S, Hammett D, Kandahari A, Khayrullina G, Kumar S, Lawrence S, Madden N, Mandelbaum M, Milnthorp H, Mohini S, Patel R, Peacock SJ, Perling E, Quintana A, Rahimi M, Ramirez K, Singhal R, Weeks C, Wong T, Gillis AT, Moore ZD, Savell CD, Watson R, Mel SF, Anilkumar AA, Bilinski P, Castillo R, Closser M, Cruz NM, Dai T, Garbagnati GF, Horton LS, Kim D, Lau JH, Liu JZ, Mach SD, Phan TA, Ren Y, Stapleton KE, Strelitz JM, Sunjed R, Stamm J, Anderson MC, Bonifield BG, Coomes D, Dillman A, Durchholz EJ, Fafara-Thompson AE, Gross MJ, Gygi AM, Jackson LE, Johnson A, Kocsisova Z, Manghelli JL, McNeil K, Murillo M, Naylor KL, Neely J, Ogawa EE, Rich A, Rogers A, Spencer JD, Stemler KM, Throm AA, Van Camp M, Weihbrecht K, Wiles TA, Williams MA, Williams M, Zoll K, Bailey C, Zhou L, Balthaser DM, Bashiri A, Bower ME, Florian KA, Ghavam N, Greiner-Sosanko ES, Karim H, Mullen VW, Pelchen CE, Yenerall PM, Zhang J, Rubin MR, Arias-Mejias SM, Bermudez-Capo AG, Bernal-Vega GV, Colon-Vazquez M, Flores-Vazquez A, Gines-Rosario M, Llavona-Cartagena IG, Martinez-Rodriguez JO, Ortiz-Fuentes L, Perez-Colomba EO, Perez-Otero J, Rivera E, Rodriguez-Giron LJ, Santiago-Sanabria AJ, Senquiz-Gonzalez AM, delValle FR, Vargas-Franco D, Velázquez-Soto KI, Zambrana-Burgos JD, Martinez-Cruzado JC, Asencio-Zayas L, Babilonia-Figueroa K, Beauchamp-Pérez FD, Belén-Rodríguez J, Bracero-Quiñones L, Burgos-Bula AP, Collado-Méndez XA, Colón-Cruz LR, Correa-Muller AI, Crooke-Rosado JL, Cruz-García JM, Defendini-Ávila M, Delgado-Peraza FM, Feliciano-Cancela AJ, Gónzalez-Pérez VM, Guiblet W, Heredia-Negrón A, Hernández-Muñiz J, Irizarry-González LN, Laboy-Corales ÁL, Llaurador-Caraballo GA, Marín-Maldonado F, Marrero-Llerena U, Martell-Martínez HA, Martínez-Traverso IM, Medina-Ortega KN, Méndez-Castellanos SG, Menéndez-Serrano KC, Morales-Caraballo CI, Ortiz-DeChoudens S, Ortiz-Ortiz P, Pagán-Torres H, Pérez-Afanador D, Quintana-Torres EM, Ramírez-Aponte EG, Riascos-Cuero C, Rivera-Llovet MS, Rivera-Pagán IT, Rivera-Vicéns RE, Robles-Juarbe F, Rodríguez-Bonilla L, Rodríguez-Echevarría BO, Rodríguez-García PM, Rodríguez-Laboy AE, Rodríguez-Santiago S, Rojas-Vargas ML, Rubio-Marrero EN, Santiago-Colón A, Santiago-Ortiz JL, Santos-Ramos CE, Serrano-González J, Tamayo-Figueroa AM, Tascón-Peñaranda EP, Torres-Castillo JL, Valentín-Feliciano NA, Valentín-Feliciano YM, Vargas-Barreto NM, Vélez-Vázquez M, Vilanova-Vélez LR, Zambrana-Echevarría C, MacKinnon C, Chung HM, Kay C, Pinto A, Kopp OR, Burkhardt J, Harward C, Allen R, Bhat P, Chang JH, Chen Y, Chesley C, Cohn D, DuPuis D, Fasano M, Fazzio N, Gavinski K, Gebreyesus H, Giarla T, Gostelow M, Greenstein R, Gunasinghe H, Hanson C, Hay A, He TJ, Homa K, Howe R, Howenstein J, Huang H, Khatri A, Kim YL, Knowles O, Kong S, Krock R, Kroll M, Kuhn J, Kwong M, Lee B, Lee R, Levine K, Li Y, Liu B, Liu L, Liu M, Lousararian A, Ma J, Mallya A, Manchee C, Marcus J, McDaniel S, Miller ML, Molleston JM, Diez CM, Ng P, Ngai N, Nguyen H, Nylander A, Pollack J, Rastogi S, Reddy H, Regenold N, Sarezky J, Schultz M, Shim J, Skorupa T, Smith K, Spencer SJ, Srikanth P, Stancu G, Stein AP, Strother M, Sudmeier L, Sun M, Sundaram V, Tazudeen N, Tseng A, Tzeng A, Venkat R, Venkataram S, Waldman L, Wang T, Yang H, Yu JY, Zheng Y, Preuss ML, Garcia A, Juergens M, Morris RW, Nagengast AA, Azarewicz J, Carr TJ, Chichearo N, Colgan M, Donegan M, Gardner B, Kolba N, Krumm JL, Lytle S, MacMillian L, Miller M, Montgomery A, Moretti A, Offenbacker B, Polen M, Toth J, Woytanowski J, Kadlec L, Crawford J, Spratt ML, Adams AL, Barnard BK, Cheramie MN, Eime AM, Golden KL, Hawkins AP, Hill JE, Kampmeier JA, Kern CD, Magnuson EE, Miller AR, Morrow CM, Peairs JC, Pickett GL, Popelka SA, Scott AJ, Teepe EJ, TerMeer KA, Watchinski CA, Watson LA, Weber RE, Woodard KA, Barnard DC, Appiah I, Giddens MM, McNeil GP, Adebayo A, Bagaeva K, Chinwong J, Dol C, George E, Haltaufderhyde K, Haye J, Kaur M, Semon M, Serjanov D, Toorie A, Wilson C, Riddle NC, Buhler J, Mardis ER, Elgin SC 2017 Drosophila Muller F elements maintain a distinct set of genomic properties over 40 million years of evolution G3 (Bethesda) 5 5 19 40
30. Liu Y, Sargent L, Leung W, Elgin SCR, Goecks J 2019 G-OnRamp: A Galaxy-based platform for collaborative annotation of eukaryotic genomes Bioinformatics 35 21 4422 4423 10.1093/bioinformatics/btz309 31070714 6821377 http://dx.doi.org/10.1093/bioinformatics/btz309
31. Hosmani PS, Shippy T, Miller S, Benoit JB, Munoz-Torres M, Flores-Gonzalez M, Mueller LA, Wiersma-Koch H, D’Elia T, Brown SJ, Saha S 2019 A quick guide for student-driven community genome annotation PLOS Comput Biol 4 e1006682 10.1371/journal.pcbi.1006682 30943207 6447164 http://dx.doi.org/10.1371/journal.pcbi.1006682
32. Stephens ZD, Lee SY, Faghri F, Campbell RH, Zhai C, Efron MJ, Iyer R, Schatz MC, Sinha S, Robinson GE 2015 Big data: astronomical or genomical? PLOS Biol 13 7 e1002195 10.1371/journal.pbio.1002195 26151137 4494865 http://dx.doi.org/10.1371/journal.pbio.1002195
33. Lopatto D 2015 Commissioned paper: the consortium as experiment Integrating discovery-based research into the undergraduate curriculum: report of a convocation The National Academies Press Washington, DC
34. Miles MB, Huberman AM 1994 Qualitative data analysis: an expanded sourcebook SAGE Thousand Oaks, CA
35. Glaser BG, Strauss AL 1967 The discovery of grounded theory: strategies for qualitative research Aldine New York, NY
36. Hsieh HF, Shannon SE 2005 Three approaches to qualitative content analysis Qual Health Res 9 1277 1288 10.1177/1049732305276687 http://dx.doi.org/10.1177/1049732305276687
37. Fattal I 2018 The value of failing The Atlantic April 25
38. Fuglei M 2017 Why students who embrace short-term failure have a better shot at long-term success Available from: https://education.cu-portland.edu/blog/classroom-resources/students-failure/ Accessed Sept. 17, 2019
39. Gabriel KF 2008 Teaching unprepared students: strategies for promoting success and retention in higher education Stylus Publishing Sterling, VA
40. Kaufman P, Schipper J 2018 Teaching with compassion Rowman and Littlefield New York, NY
41. Lin-Siegler X, Ahn JN, Chen J 2016 Even Einstein struggled: effects of learning about great scientists’ struggles on high school students’ motivation to learn science J Educ Psych 108 3 314 328 10.1037/edu0000092 http://dx.doi.org/10.1037/edu0000092
42. Auchincloss LC, Laursen SL, Branchaw JL, Eagan K, Graham M, Hanauer DI, Lawrie G, McLinn CM, Pelaez N, Rowland S, Towns M, Trautmann NM, Varma-Nelson P, Weston TJ, Dolan EL 2014 Assessment of course-based undergraduate research experiences: a meeting report CBE Life Sci Educ 3 1 29 40 10.1187/cbe.14-01-0004 http://dx.doi.org/10.1187/cbe.14-01-0004
43. Lopatto D 2009 Science in solution: the impact of undergraduate research on student learning Research Corporation Tucson, AZ
44. Handelsman J, Pfund C, Lauffer SM, Pribbenow CM 2005 Entering mentoring The Wisconsin Program for Scientific Teaching Madison, WI
45. Kirkpatrick C, Schuchardt A, Baltz D, Cotner S 2019 Computer-based and bench-based undergraduate research experiences produce similar attitudinal outcomes CBE Life Sci Educ 18 1 ar10 10.1187/cbe.18-07-0112 30821601 6757217 http://dx.doi.org/10.1187/cbe.18-07-0112
46. Gin LE, Rowland AA, Steinwand B, Bruno J, Corwin LA 2018 Students who fail to achieve predefined research goals may still experience many positive outcomes as a result of CURE participation CBE Life Sci Educ 17 4 ar57 10.1187/cbe.18-03-0036 30417757 6755884 http://dx.doi.org/10.1187/cbe.18-03-0036
47. Hunter AB, Laursen SL, Seymour E 2006 Becoming a scientist: the role of undergraduate research in students’ cognitive, personal, and professional development Sci Educ 91 1 36 74 10.1002/sce.20173 http://dx.doi.org/10.1002/sce.20173
48. Fiedler FE 1987 When to lead, when to stand back Psychol Today 21 9 26 27

Supplemental Material

Loading

Article metrics loading...

/content/journal/jmbe/10.1128/jmbe.v21i1.2005
2020-02-28
2020-05-25

Abstract:

A hallmark of the research experience is encountering difficulty and working through those challenges to achieve success. This ability is essential to being a successful scientist, but replicating such challenges in a teaching setting can be difficult. The Genomics Education Partnership (GEP) is a consortium of faculty who engage their students in a genomics Course-Based Undergraduate Research Experience (CURE). Students participate in genome annotation, generating gene models using multiple lines of experimental evidence. Our observations suggested that the students’ learning experience is continuous and recursive, frequently beginning with frustration but eventually leading to success as they come up with defendable gene models. In order to explore our “formative frustration” hypothesis, we gathered data from faculty via a survey, and from students via both a general survey and a set of student focus groups. Upon analyzing these data, we found that all three datasets mentioned frustration and struggle, as well as learning and better understanding of the scientific process. Bioinformatics projects are particularly well suited to the process of iteration and refinement because iterations can be performed quickly and are inexpensive in both time and money. Based on these findings, we suggest that a dynamic of “formative frustration” is an important aspect for a successful CURE.

Highlighted Text: Show | Hide
Loading full text...

Full text loading...

/deliver/fulltext/jmbe/21/1/jmbe-21-6.html?itemId=/content/journal/jmbe/10.1128/jmbe.v21i1.2005&mimeType=html&fmt=ahah

Author and Article Information

  • Received 16 October 2019 Accepted 23 January 2020 Published 28 February 2020
  • ©2020 Author(s). Published by the American Society for Microbiology

  • [open-access] This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-NoDerivatives 4.0 International license (https://creativecommons.org/licenses/by-nc-nd/4.0/ and https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode), which grants the public the nonexclusive right to copy, distribute, or display the published work.
  • †Supplemental materials available at http://asmscience.org/jmbe
  • *Corresponding author. Mailing address: Biology Department, Georgetown University, 306 Regents Hall, 37th and O Sts, NW, Washington, DC 20057. Phone: 202-687-5997. E-mail [email protected]

Figures

Facilitating Growth through Frustration: Using Genomics Research in a Course-Based Undergraduate Research Experience
[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-1,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-1,properties={foaf_givenname=David, foaf_name=David Lopatto, foaf_surname=Lopatto, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff1]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-2,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-2,properties={foaf_givenname=Anne G., foaf_name=Anne G. Rosenwald, foaf_surname=Rosenwald, pub_correspondenceLink=*, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff2]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-3,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-3,properties={foaf_givenname=Justin R., foaf_name=Justin R. DiAngelo, foaf_surname=DiAngelo, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff3]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-4,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-4,properties={foaf_givenname=Amy T., foaf_name=Amy T. Hark, foaf_surname=Hark, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff4]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-5,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-5,properties={foaf_givenname=Matthew, foaf_name=Matthew Skerritt, foaf_surname=Skerritt, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff5]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-6,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-6,properties={foaf_givenname=Matthew, foaf_name=Matthew Wawersik, foaf_surname=Wawersik, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff6]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-7,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-7,properties={foaf_givenname=Anna K., foaf_name=Anna K. Allen, foaf_surname=Allen, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff7]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-8,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-8,properties={foaf_givenname=Consuelo, foaf_name=Consuelo Alvarez, foaf_surname=Alvarez, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff8]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-9,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-9,properties={foaf_givenname=Sara, foaf_name=Sara Anderson, foaf_surname=Anderson, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff9]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-10,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-10,properties={foaf_givenname=Cindy, foaf_name=Cindy Arrigo, foaf_surname=Arrigo, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff10]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-11,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-11,properties={foaf_givenname=Andrew, foaf_name=Andrew Arsham, foaf_surname=Arsham, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff11]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-12,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-12,properties={foaf_givenname=Daron, foaf_name=Daron Barnard, foaf_surname=Barnard, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff12]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-13,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-13,properties={foaf_givenname=Christopher, foaf_name=Christopher Bazinet, foaf_surname=Bazinet, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff13]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-14,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-14,properties={foaf_givenname=James E. J., foaf_name=James E. J. Bedard, foaf_surname=Bedard, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff14]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-15,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-15,properties={foaf_givenname=Indrani, foaf_name=Indrani Bose, foaf_surname=Bose, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff15]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-16,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-16,properties={foaf_givenname=John M., foaf_name=John M. Braverman, foaf_surname=Braverman, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff16]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-17,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-17,properties={foaf_givenname=Martin G., foaf_name=Martin G. Burg, foaf_surname=Burg, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff17]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-18,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-18,properties={foaf_givenname=Rebecca C., foaf_name=Rebecca C. Burgess, foaf_surname=Burgess, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff18]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-19,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-19,properties={foaf_givenname=Paula, foaf_name=Paula Croonquist, foaf_surname=Croonquist, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff19]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-20,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-20,properties={foaf_givenname=Chunguang, foaf_name=Chunguang Du, foaf_surname=Du, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff20]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-21,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-21,properties={foaf_givenname=Sondra, foaf_name=Sondra Dubowsky, foaf_surname=Dubowsky, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff21]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-22,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-22,properties={foaf_givenname=Heather, foaf_name=Heather Eisler, foaf_surname=Eisler, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff22]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-23,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-23,properties={foaf_givenname=Matthew A., foaf_name=Matthew A. Escobar, foaf_surname=Escobar, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff23]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-24,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-24,properties={foaf_givenname=Michael, foaf_name=Michael Foulk, foaf_surname=Foulk, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff24]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-25,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-25,properties={foaf_givenname=Emily, foaf_name=Emily Furbee, foaf_surname=Furbee, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff25]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-26,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-26,properties={foaf_givenname=Thomas, foaf_name=Thomas Giarla, foaf_surname=Giarla, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff26]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-27,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-27,properties={foaf_givenname=Rivka L., foaf_name=Rivka L. Glaser, foaf_surname=Glaser, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff27]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-28,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-28,properties={foaf_givenname=Anya L., foaf_name=Anya L. Goodman, foaf_surname=Goodman, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff28]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-29,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-29,properties={foaf_givenname=Yuying, foaf_name=Yuying Gosser, foaf_surname=Gosser, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff29]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-30,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-30,properties={foaf_givenname=Adam, foaf_name=Adam Haberman, foaf_surname=Haberman, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff30]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-31,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-31,properties={foaf_givenname=Charles, foaf_name=Charles Hauser, foaf_surname=Hauser, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff31]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-32,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-32,properties={foaf_givenname=Shan, foaf_name=Shan Hays, foaf_surname=Hays, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff32]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-33,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-33,properties={foaf_givenname=Carina E., foaf_name=Carina E. Howell, foaf_surname=Howell, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff33]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-34,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-34,properties={foaf_givenname=Jennifer, foaf_name=Jennifer Jemc, foaf_surname=Jemc, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff34]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-35,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-35,properties={foaf_givenname=M. Logan, foaf_name=M. Logan Johnson, foaf_surname=Johnson, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff35]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-36,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-36,properties={foaf_givenname=Christopher J., foaf_name=Christopher J. Jones, foaf_surname=Jones, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff36]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-37,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-37,properties={foaf_givenname=Lisa, foaf_name=Lisa Kadlec, foaf_surname=Kadlec, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff37]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-38,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-38,properties={foaf_givenname=Jacob D., foaf_name=Jacob D. Kagey, foaf_surname=Kagey, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff38]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-39,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-39,properties={foaf_givenname=Kimberly L., foaf_name=Kimberly L. Keller, foaf_surname=Keller, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff39]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-40,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-40,properties={foaf_givenname=Jennifer, foaf_name=Jennifer Kennell, foaf_surname=Kennell, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff40]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-41,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-41,properties={foaf_givenname=S. Catherine Silver, foaf_name=S. Catherine Silver Key, foaf_surname=Key, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff41]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-42,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-42,properties={foaf_givenname=Adam J., foaf_name=Adam J. Kleinschmit, foaf_surname=Kleinschmit, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff42]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-43,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-43,properties={foaf_givenname=Melissa, foaf_name=Melissa Kleinschmit, foaf_surname=Kleinschmit, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff42]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-44,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-44,properties={foaf_givenname=Nighat P., foaf_name=Nighat P. Kokan, foaf_surname=Kokan, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff43]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-45,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-45,properties={foaf_givenname=Olga Ruiz, foaf_name=Olga Ruiz Kopp, foaf_surname=Kopp, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff44]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-46,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-46,properties={foaf_givenname=Meg M., foaf_name=Meg M. Laakso, foaf_surname=Laakso, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff45]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-47,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-47,properties={foaf_givenname=Judith, foaf_name=Judith Leatherman, foaf_surname=Leatherman, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff46]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-48,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-48,properties={foaf_givenname=Lindsey J., foaf_name=Lindsey J. Long, foaf_surname=Long, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff47]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-49,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-49,properties={foaf_givenname=Mollie, foaf_name=Mollie Manier, foaf_surname=Manier, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff48]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-50,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-50,properties={foaf_givenname=Juan C., foaf_name=Juan C. Martinez-Cruzado, foaf_surname=Martinez-Cruzado, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff49]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-51,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-51,properties={foaf_givenname=Luis F., foaf_name=Luis F. Matos, foaf_surname=Matos, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff50]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-52,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-52,properties={foaf_givenname=Amie Jo, foaf_name=Amie Jo McClellan, foaf_surname=McClellan, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff51]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-53,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-53,properties={foaf_givenname=Gerard, foaf_name=Gerard McNeil, foaf_surname=McNeil, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff52]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-54,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-54,properties={foaf_givenname=Evan, foaf_name=Evan Merkhofer, foaf_surname=Merkhofer, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff53]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-55,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-55,properties={foaf_givenname=Vida, foaf_name=Vida Mingo, foaf_surname=Mingo, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff54]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-56,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-56,properties={foaf_givenname=Hemlata, foaf_name=Hemlata Mistry, foaf_surname=Mistry, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff55]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-57,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-57,properties={foaf_givenname=Elizabeth, foaf_name=Elizabeth Mitchell, foaf_surname=Mitchell, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff21]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-58,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-58,properties={foaf_givenname=Nathan T., foaf_name=Nathan T. Mortimer, foaf_surname=Mortimer, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff56]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-59,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-59,properties={foaf_givenname=Debaditya, foaf_name=Debaditya Mukhopadhyay, foaf_surname=Mukhopadhyay, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff57]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-60,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-60,properties={foaf_givenname=Jennifer Leigh, foaf_name=Jennifer Leigh Myka, foaf_surname=Myka, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff58]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-61,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-61,properties={foaf_givenname=Alexis, foaf_name=Alexis Nagengast, foaf_surname=Nagengast, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff59]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-62,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-62,properties={foaf_givenname=Paul, foaf_name=Paul Overvoorde, foaf_surname=Overvoorde, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff60]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-63,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-63,properties={foaf_givenname=Don, foaf_name=Don Paetkau, foaf_surname=Paetkau, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff61]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-64,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-64,properties={foaf_givenname=Leocadia, foaf_name=Leocadia Paliulis, foaf_surname=Paliulis, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff62]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-65,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-65,properties={foaf_givenname=Susan, foaf_name=Susan Parrish, foaf_surname=Parrish, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff63]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-66,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-66,properties={foaf_givenname=Mary Lai, foaf_name=Mary Lai Preuss, foaf_surname=Preuss, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff64]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-67,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-67,properties={foaf_givenname=James V., foaf_name=James V. Price, foaf_surname=Price, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff44]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-68,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-68,properties={foaf_givenname=Nicholas A., foaf_name=Nicholas A. Pullen, foaf_surname=Pullen, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff65]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-69,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-69,properties={foaf_givenname=Catherine, foaf_name=Catherine Reinke, foaf_surname=Reinke, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff66]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-70,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-70,properties={foaf_givenname=Dennis, foaf_name=Dennis Revie, foaf_surname=Revie, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff67]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-71,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-71,properties={foaf_givenname=Srebrenka, foaf_name=Srebrenka Robic, foaf_surname=Robic, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff68]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-72,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-72,properties={foaf_givenname=Jennifer A., foaf_name=Jennifer A. Roecklein-Canfield, foaf_surname=Roecklein-Canfield, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff69]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-73,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-73,properties={foaf_givenname=Michael R., foaf_name=Michael R. Rubin, foaf_surname=Rubin, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff70]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-74,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-74,properties={foaf_givenname=Takrima, foaf_name=Takrima Sadikot, foaf_surname=Sadikot, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff71]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-75,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-75,properties={foaf_givenname=Jamie Siders, foaf_name=Jamie Siders Sanford, foaf_surname=Sanford, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff72]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-76,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-76,properties={foaf_givenname=Maria, foaf_name=Maria Santisteban, foaf_surname=Santisteban, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff73]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-77,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-77,properties={foaf_givenname=Kenneth, foaf_name=Kenneth Saville, foaf_surname=Saville, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff74]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-78,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-78,properties={foaf_givenname=Stephanie, foaf_name=Stephanie Schroeder, foaf_surname=Schroeder, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff64]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-79,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-79,properties={foaf_givenname=Christopher D., foaf_name=Christopher D. Shaffer, foaf_surname=Shaffer, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff75]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-80,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-80,properties={foaf_givenname=Karim A., foaf_name=Karim A. Sharif, foaf_surname=Sharif, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff76]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-81,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-81,properties={foaf_givenname=Diane E., foaf_name=Diane E. Sklensky, foaf_surname=Sklensky, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff77]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-82,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-82,properties={foaf_givenname=Chiyedza, foaf_name=Chiyedza Small, foaf_surname=Small, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff78]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-83,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-83,properties={foaf_givenname=Mary, foaf_name=Mary Smith, foaf_surname=Smith, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff79]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-84,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-84,properties={foaf_givenname=Sheryl, foaf_name=Sheryl Smith, foaf_surname=Smith, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff80]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-85,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-85,properties={foaf_givenname=Rebecca, foaf_name=Rebecca Spokony, foaf_surname=Spokony, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff81]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-86,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-86,properties={foaf_givenname=Aparna, foaf_name=Aparna Sreenivasan, foaf_surname=Sreenivasan, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff82]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-87,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-87,properties={foaf_givenname=Joyce, foaf_name=Joyce Stamm, foaf_surname=Stamm, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff83]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-88,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-88,properties={foaf_givenname=Rachel, foaf_name=Rachel Sterne-Marr, foaf_surname=Sterne-Marr, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff84]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-89,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-89,properties={foaf_givenname=Katherine C., foaf_name=Katherine C. Teeter, foaf_surname=Teeter, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff85]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-90,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-90,properties={foaf_givenname=Justin, foaf_name=Justin Thackeray, foaf_surname=Thackeray, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff86]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-91,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-91,properties={foaf_givenname=Jeffrey S., foaf_name=Jeffrey S. Thompson, foaf_surname=Thompson, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff87]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-92,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-92,properties={foaf_givenname=Stephanie Toering, foaf_name=Stephanie Toering Peters, foaf_surname=Peters, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff88]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-93,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-93,properties={foaf_givenname=Melanie, foaf_name=Melanie Van Stry, foaf_surname=Van Stry, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff89]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-94,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-94,properties={foaf_givenname=Norma, foaf_name=Norma Velazquez-Ulloa, foaf_surname=Velazquez-Ulloa, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff90]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-95,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-95,properties={foaf_givenname=Cindy, foaf_name=Cindy Wolfe, foaf_surname=Wolfe, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff91]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-96,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-96,properties={foaf_givenname=James, foaf_name=James Youngblom, foaf_surname=Youngblom, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff92]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-97,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-97,properties={foaf_givenname=Brian, foaf_name=Brian Yowler, foaf_surname=Yowler, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff93]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-98,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-98,properties={foaf_givenname=Leming, foaf_name=Leming Zhou, foaf_surname=Zhou, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff94]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-99,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-99,properties={foaf_givenname=Janie, foaf_name=Janie Brennan, foaf_surname=Brennan, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff95]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-100,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-100,properties={foaf_givenname=Jeremy, foaf_name=Jeremy Buhler, foaf_surname=Buhler, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff96]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-101,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-101,properties={foaf_givenname=Wilson, foaf_name=Wilson Leung, foaf_surname=Leung, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff75]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-102,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-102,properties={foaf_givenname=Laura K., foaf_name=Laura K. Reed, foaf_surname=Reed, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff97]]}], com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/author/jmbe/10.1128/jmbe.v21i1.2005-103,webId=/content/author/jmbe/10.1128/jmbe.v21i1.2005-103,properties={foaf_givenname=Sarah C. R., foaf_name=Sarah C. R. Elgin, foaf_surname=Elgin, pub_isAffiliatedWith=[com.pub2web.rdf.cci.facet.ContentItem[id=http://asm.metastore.ingenta.com/content/affiliation/jmbe/10.1128/jmbe.v21i1.2005-aff75]]}]]
Citation: Lopatto D, Rosenwald A, DiAngelo J, Hark A, Skerritt M, Wawersik M, Allen A, Alvarez C, Anderson S, Arrigo C, Arsham A, Barnard D, Bazinet C, Bedard J, Bose I, Braverman J, Burg M, Burgess R, Croonquist P, Du C, Dubowsky S, Eisler H, Escobar M, Foulk M, Furbee E, Giarla T, Glaser R, Goodman A, Gosser Y, Haberman A, Hauser C, Hays S, Howell C, Jemc J, Johnson M, Jones C, Kadlec L, Kagey J, Keller K, Kennell J, Key S, Kleinschmit A, Kleinschmit M, Kokan N, Kopp O, Laakso M, Leatherman J, Long L, Manier M, Martinez-Cruzado J, Matos L, McClellan A, McNeil G, Merkhofer E, Mingo V, Mistry H, Mitchell E, Mortimer N, Mukhopadhyay D, Myka J, Nagengast A, Overvoorde P, Paetkau D, Paliulis L, Parrish S, Preuss M, Price J, Pullen N, Reinke C, Revie D, Robic S, Roecklein-Canfield J, Rubin M, Sadikot T, Sanford J, Santisteban M, Saville K, Schroeder S, Shaffer C, Sharif K, Sklensky D, Small C, Smith M, Smith S, Spokony R, Sreenivasan A, Stamm J, Sterne-Marr R, Teeter K, Thackeray J, Thompson J, Peters S, Van Stry M, Velazquez-Ulloa N, Wolfe C, Youngblom J, Yowler B, Zhou L, Brennan J, Buhler J, Leung W, Reed L, Elgin S. 2020. Facilitating growth through frustration: using genomics research in a course-based undergraduate research experience . J. Microbiol. Biol. Educ. 21(1): doi:10.1128/jmbe.v21i1.2005
/content/jmbe/10.1128/jmbe.v21i1.2005.f1-jmbe-21-6
FIGURE 1
The GEP mirror of the UCSC Genome Browser for (Sept 2008 GEP/dot assembly), with lines of evidence supporting the presence of a protein-coding gene in this region. The genome sequence is shown in the top line (Improved Sequence), with multiple lines of evidence supporting the presence of a gene mapped against that sequence. There are apparent contradictions in these evidence tracks. The BLASTx alignment track indicates that the region at 93000–12000 of shows significant similarity to protein sequences for two isoforms of the gene (Sequence Homology track). Computer-based gene predictors indicate a gene in this region (Gene Predictions tracks), but vary on the number, size, and location of predicted exons. RNA-Seq data appear to support the presence of three or four exons, yet TopHat and Cufflinks differ on the number and location of intron splice sites. The region from 7500 to 8000 might contain an exon of (predicted by N-SCAN), or it might be a separate gene (predicted by Genscan and SGP) as there is some RNA-Seq data, but little or no conservation is indicated in this region. Students must reconcile these differences to generate the best-supported gene models for this region of the genome.
jmbe/21/1/jmbe-21-6f1_thmb.gif
jmbe/21/1/jmbe-21-6f1.gif
Image of FIGURE 1

Click to view

FIGURE 1

The GEP mirror of the UCSC Genome Browser for (Sept 2008 GEP/dot assembly), with lines of evidence supporting the presence of a protein-coding gene in this region. The genome sequence is shown in the top line (Improved Sequence), with multiple lines of evidence supporting the presence of a gene mapped against that sequence. There are apparent contradictions in these evidence tracks. The BLASTx alignment track indicates that the region at 93000–12000 of shows significant similarity to protein sequences for two isoforms of the gene (Sequence Homology track). Computer-based gene predictors indicate a gene in this region (Gene Predictions tracks), but vary on the number, size, and location of predicted exons. RNA-Seq data appear to support the presence of three or four exons, yet TopHat and Cufflinks differ on the number and location of intron splice sites. The region from 7500 to 8000 might contain an exon of (predicted by N-SCAN), or it might be a separate gene (predicted by Genscan and SGP) as there is some RNA-Seq data, but little or no conservation is indicated in this region. Students must reconcile these differences to generate the best-supported gene models for this region of the genome.

Source: J. Microbiol. Biol. Educ. February 2020 vol. 21 no. 1 doi:10.1128/jmbe.v21i1.2005
Download as Powerpoint
/content/jmbe/10.1128/jmbe.v21i1.2005.f2-jmbe-21-6
FIGURE 2
Faculty observe that setbacks in the research process promote student learning. Results from analysis of comments from the Formative Failure faculty survey ( Appendix 2 ) on the effects on student learning from course setbacks (survey question 9.D: problems affecting all students in the class, =161) and student setbacks (survey question 10.D: problems encountered by individual students, =134). The percent of faculty responses that were positive (blue), negative (orange), or neutral (no effect; grey) are shown. GEP = Genomics Education Partnership.
jmbe/21/1/jmbe-21-6f2_thmb.gif
jmbe/21/1/jmbe-21-6f2.gif
Image of FIGURE 2

Click to view

FIGURE 2

Faculty observe that setbacks in the research process promote student learning. Results from analysis of comments from the Formative Failure faculty survey ( Appendix 2 ) on the effects on student learning from course setbacks (survey question 9.D: problems affecting all students in the class, =161) and student setbacks (survey question 10.D: problems encountered by individual students, =134). The percent of faculty responses that were positive (blue), negative (orange), or neutral (no effect; grey) are shown. GEP = Genomics Education Partnership.

Source: J. Microbiol. Biol. Educ. February 2020 vol. 21 no. 1 doi:10.1128/jmbe.v21i1.2005
Download as Powerpoint
/content/jmbe/10.1128/jmbe.v21i1.2005.f3-jmbe-21-6
FIGURE 3
Faculty are more likely to let their students risk failure in GEP research projects than in wet bench or field work lab courses and research projects. Faculty were asked how likely they were to let students fail in performance of wet bench lab work (coursework and research), field work (coursework or research), and GEP research activities. The degree of willingness to risk failure was evaluated as 1 (very likely) to 3 (not at all). Note that many GEP faculty members do not do field work, so the number of responses in that category is lower. (Percentages do not sum to 100%, as “not applicable” responses are not shown.) GEP = Genomics Education Partnership.
jmbe/21/1/jmbe-21-6f3_thmb.gif
jmbe/21/1/jmbe-21-6f3.gif
Image of FIGURE 3

Click to view

FIGURE 3

Faculty are more likely to let their students risk failure in GEP research projects than in wet bench or field work lab courses and research projects. Faculty were asked how likely they were to let students fail in performance of wet bench lab work (coursework and research), field work (coursework or research), and GEP research activities. The degree of willingness to risk failure was evaluated as 1 (very likely) to 3 (not at all). Note that many GEP faculty members do not do field work, so the number of responses in that category is lower. (Percentages do not sum to 100%, as “not applicable” responses are not shown.) GEP = Genomics Education Partnership.

Source: J. Microbiol. Biol. Educ. February 2020 vol. 21 no. 1 doi:10.1128/jmbe.v21i1.2005
Download as Powerpoint
/content/jmbe/10.1128/jmbe.v21i1.2005.f4-jmbe-21-6
FIGURE 4
Genomics-based CUREs can support an iterative learning process. A collaborative Learning Environment (1) supports the entire process, which includes a defined learning objective (2), a formative strategy (3), and iterative experimentation (4). Adapted with permission from ( 10 ).
jmbe/21/1/jmbe-21-6f4_thmb.gif
jmbe/21/1/jmbe-21-6f4.gif
Image of FIGURE 4

Click to view

FIGURE 4

Genomics-based CUREs can support an iterative learning process. A collaborative Learning Environment (1) supports the entire process, which includes a defined learning objective (2), a formative strategy (3), and iterative experimentation (4). Adapted with permission from ( 10 ).

Source: J. Microbiol. Biol. Educ. February 2020 vol. 21 no. 1 doi:10.1128/jmbe.v21i1.2005
Download as Powerpoint

Back to top
This is a required field
Please enter a valid email address
Please check the format of the address you have entered.
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error