Microbe Magazine

June 2014

Cover Image
Cover Image

Cover: Wild boar (Sus scrofa) populations are serving as reservoirs for infectious diseases that affect both domestic animals and humans (see p. 226). (Image © iStockphoto/johan10.)

Microbe Magazine, Cover Image
Cover Image

Cover: Wild boar (Sus scrofa) populations are serving as reservoirs for infectious diseases that affect both domestic animals and humans (see p. 226). (Image © iStockphoto/johan10.)


  • Meet Alice C. Evans
    Image of Author: Lorraine Findlay

    Alice C. Evans (1881–1975), the first woman president of ASM, was elected in 1928 when the society was known as the Society of American Bacteriologists. In many ways, the achievements of women in ASM build on her pioneering efforts from an era that offered far fewer opportunities for women scient... More...

  • Virulence Factors Thwart Host Immune Responses
    Image of Authors: Tamara Reyes-Robles, Francis Alonzo III, and Victor J. Torres

    To thrive within immunocompetent human hosts, pathogenic microorganisms adapt to and resist both innate and adaptive immune responses. For example, the gram-positive bacterium is highly efficient at infecting humans and evading host immunity. A... More...

  • Epstein-Barr Virus: Cell Trafficking Is Crucial for Persistence
    Image of Author: Lindsey Hutt-Fletcher

    Herpesviruses, large enveloped viruses with double-stranded linear genomes, are particularly adept at overcoming immune system and other challenges while persisting within host cells. In particular, Epstein-Barr virus (EBV), one of the eight known human herpesviruses, typically persists for life ... More...


  • Resurgent Interest in Plant-Based Vaccines, Monoclonal Antibodies
    Image of Author: Jeffrey L. Fox

    After technical strategies for using plants to produce vaccines, monoclonal antibodies (mAbs), or other therapeutic or protective proteins and glycoproteins improved during the past decade, enthusiasm for these newer approaches grew because the products are proving effective, according to several... More...

  • Surprise: Thioredoxins from Plants Found in Anaerobic Methanogen
    Author: Barry E. DiGregorio

    Archaeal methanogens began producing thioredoxin (Trx) regulatory proteins, several of which are active in regulating physiology in green plants, long before photosynthesis arose, according to Biswarup Mukhopadhyay from Virginia Polytechnic Institute and State University in Blacksburg and his col... More...

  • Phenazine-Detecting Chips Can Follow Bacterial Physiology in Biofilms
    Author: Carol Potera

    Integrated circuits, designed to respond to specific metabolites, are now being used to detect signaling in microbial biofilms and someday might be used to disrupt those biofilms, according to Lars Dietrich and other biologists and electrical engineers at Columbia University in New York, N.Y. Det... More...

  • Periodontal Pathogens from Medieval Teeth: Same Old, Same Old
    Author: John Otrompke

    Analyses of DNA and proteins harvested from the dental calculus of four human skeletons in a 1,000-year-old graveyard and then subjected to protein and DNA sequencing as well as tandem mass spectrometry provide “a detailed picture of periodontal disease 1,000 years ago,” says Christina Warinner o... More...

  • Now in the Caribbean, Chikungunya Virus Is Poised for the Americas
    Image of Author: David C. Holzman

    The chikungunya virus is poised to invade the Americas, threatening to start an epidemic, according to Ricardo Lourenço-de-Oliveira of Instituto Oswaldo Cruz in Rio de Janeiro, Brazil, Anna-Bella Failloux of the Pasteur Institute in Paris, France, and their collaborators. Details appeared 26 Marc... More...

  • Abundant Ultra-Small Microbial Cells in the Lake Vida Ice Cover
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    The complexity of life in earth's extreme ecosystems continues to provide evidence supporting the boundaries of where, and under what circumstances, life can exist. Emanuele Kuhn and Alison Murray of the Desert Research Institute, Reno, Nev., et al. describe the morphological structure and p... More...

  • Tomato Turf Wars: Benign Bug Bests , Tomato Eaters Win
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    spp. thrive in the same conditions under which raw tomatoes are grown, and outbreaks traced to raw tomatoes have sickened nearly 2,000 people in the United States from 2000–2010, killing three. Now a bacterium, More...

  • Potential Cure for Captive Amphibians with Chytrid Fungus
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    The fungal skin disease chytridiomycosis, caused by , has been decimating amphibians worldwide. Zoos have been acquiring “founding populations” of threatened species. They currently rely on the relatively toxic itraconazole to eradicate... More...

  • Antarctic Penguins Carry Avian Flu Virus
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    To some extent, live at the mercy of avian influenza viruses—where they migrate, and how they mutate in ways that may result in their infecting livestock or humans. Now, for the first time, investigators report the discovery of avian influenza viruses i... More...

  • Same MRSA in People and Their Animals
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    Methicillin-resistant (MRSA) poses a major threat to global health. Now Ewan M. Harrison and Mark A. Holmes of the University of Cambridge, United Kingdom (UK), et al. show that the main health care-associated MRSA lineage in the UK is also fou... More...

  • Fidelity of Histone Gene Regulation Is Obligatory
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    Fidelity of chromatin organization is crucial for normal cell cycle progression, and perturbations in packaging of DNA may predispose to transformation. Gary S. Stein of the University of Vermont College of Medicine, Burlington, et al. present direct evidence that the tight coupling of DNA replic... More...



  • Application Deadlines

    ASM General Meeting Awards. Awards presented at the ASM General Meeting honor outstanding achievements in research, education, service, and students and young investigators. Please consider nominating colleagues or students you feel are deserving of an ASM award. The deadli... More...

  • ASM Meetings Calendar

    19–22 June 2014.

  • Employment
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  • Small Things Considered
    Image of Author: S. Marvin Friedman

    The disconcerting ability of bacteria to evade death from treatment with antibiotics is achieved with two distinct strategies, resistance and tolerance. Resistance occurs by a variety of mechanisms, including drug efflux and/or modifying either the drug or its target. Tolerance, on the other hand... More...


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